WordNet

of or relating to a hemorrhage (同)haemorrhagic
a rare autosomal recessive disease in which the platelets do not produce clots in the normal way and hemorrhage results

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1. 出血性素因を有する成人患者へのアプローチ approach to the adult patient with a bleeding diathesis
2. 出血症状を有する小児に対するアプローチ approach to the child with bleeding symptoms
3. 先天性および後天性血小板機能障害 congenital and acquired disorders of platelet function
4. 思春期の女性に生じる不正子宮出血：評価と診断法 abnormal uterine bleeding in adolescents evaluation and approach to diagnosis
5. 潜在性消化管出血の評価 evaluation of occult gastrointestinal bleeding

Immunisation against αIIbβ3 and αvβ3 in a type 1 variant of Glanzmann's thrombasthenia caused by a missense mutation Gly540Asp on β3.

Wihadmadyatami H, Röder L, Berghöfer H, Bein G, Heidinger K, Sachs UJ, Santoso S1.
Thrombosis and haemostasis.Thromb Haemost.2016 Apr 21;116(2). [Epub ahead of print]
Treatment of bleeding in patients with Glanzmann's thrombasthenia (GT) can be hampered by iso-antibodies against the αIIbβ3 integrin, which cause rapid clearance of transfused donor platelets. Type 1 GT patients with a total absence of αIIbβ3 from the platelet surface are known to be susceptible
PMID 27098940

The utility of International Society on Thrombosis and Haemostasis-Bleeding Assessment Tool and other bleeding questionnaires in assessing the bleeding phenotype in two platelet function defects.

Kaur H1, Borhany M, Azzam H, Costa-Lima C, Ozelo M, Othman M.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.Blood Coagul Fibrinolysis.2016 Apr 20. [Epub ahead of print]
The main objective of this study is to investigate the utility of International Society on Thrombosis and Haemostasis-Bleeding Assessment Tool (ISTH-BAT) in comparison with the condensed form of Molecular and Clinical Markers for the Diagnosis and Management of type 1 and WHO BATs, in assessing blee
PMID 27100304

Coated platelets function in platelet-dependent fibrin formation via integrin αIIbβ3 and transglutaminase factor XIII.

Mattheij NJ1, Swieringa F1, Mastenbroek TG1, Berny-Lang MA2, May F3, Baaten CC1, van der Meijden PE1, Henskens YM4, Beckers EA5, Suylen DP1, Nolte MW3, Hackeng TM1, McCarty OJ2, Heemskerk JW1, Cosemans JM6.
Haematologica.Haematologica.2016 Apr;101(4):427-36. doi: 10.3324/haematol.2015.131441. Epub 2015 Dec 31.
Coated platelets, formed by collagen and thrombin activation, have been characterized in different ways: i) by the formation of a protein coat of α-granular proteins; ii) by exposure of procoagulant phosphatidylserine; or iii) by high fibrinogen binding. Yet, their functional role has remained uncl
PMID 26721892

森田久男,橋本忠夫,加々美光安,渡辺朋郎,河本泰彦,江幡良子
臨床血液 8(2), 125-130, 1967
… A 16 years old female with thrombasthenia (Glanzmann) was reported. … She had no proved hereditary consequence, but seemed to be congenital., because of the consanguinity of her parents.The laboratory findings on her blood were quite similar to that of 5 cases previously reported by us, She had slight splenomegaly and thrombocytopenia which might have some co-relation between them. …
NAID 130004501889