WordNet

pertaining to or affecting the liver; "hepatic ducts"; "hepatic cirrhosis"
any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions

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1. 肝酵素および肝機能検査値の異常が認められた患者に対するアプローチ approach to the patient with abnormal liver biochemical and function tests
2. 肝細胞障害を検出するための肝臓生化学検査 liver biochemical tests that detect injury to hepatocytes
3. 嚢胞性線維症：肝胆道系疾患 cystic fibrosis hepatobiliary disease
4. 2型糖尿病の治療に用いるジペプチジルペプチダーゼ4（DPP-4）阻害薬 dipeptidyl peptidase 4 dpp 4 inhibitors for the treatment of type 2 diabetes mellitus
5. 肝線維症の非侵襲的評価：血清学的検査および画像診断 noninvasive assessment of hepatic fibrosis overview of serologic and radiographic tests

Stine JG1, Chalasani NP2.
Clinics in liver disease.Clin Liver Dis.2017 Feb;21(1):103-113. doi: 10.1016/j.cld.2016.08.008. Epub 2016 Oct 13.
Drug-induced liver injury presents as various forms of acute and chronic liver disease. There is wide geographic variation in the most commonly implicated agents. Smoking can induce cytochrome P450 enzymes but this does not necessarily translate into clinically relevant drug-induced liver injury. Ex
PMID 27842766

Study the influence of licorice and pomegranate drinks on nicotine metabolism in human urine by LC-orbitrap MS.

Abu-Awwad A1, Arafat T2, Schmitz OJ3.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2017 Jan 5;132:60-65. doi: 10.1016/j.jpba.2016.09.026. Epub 2016 Sep 28.
Nicotine-diet interactions have a particular importance on human health. Some food substances are subject to change hepatic CYP2A6 metabolism rate for nicotine and its levels in smokers consequently. This study investigates the effect of pomegranate and licorice drinks on nicotine metabolism, by a n
PMID 27693954

Pentachlorophenol affected both reproductive and interrenal systems: In silico and in vivo evidence.

Yang L1, Zha J2, Wang Z3.
Chemosphere.Chemosphere.2017 Jan;166:174-183. doi: 10.1016/j.chemosphere.2016.09.099. Epub 2016 Sep 30.
The present study investigated the effects on reproductive and interrenal system by pentachlorophenol (PCP) using in silico and in vivo assays. Molecular docking results indicated interacting potency of PCP with steroid receptors (ERα, ERβ, AR, GR) but not Cytochrome P450 enzymes (CYPs). In the i
PMID 27697705

脂溶性ビタミンと遺伝子多型 : 代謝および臨床との関連(<特集>第66回大会シンポジウム「栄養と臨床におけるビタミンの遺伝子多型に基づいたテーラーメイド摂取の有用性」)

瀧谷公隆
ビタミン 89(2), 65-71, 2015-02-25
… CYP26B1 is the metabolizing enzyme of retinoic acid. … CYP4F2 polymorphism affected vitamin E pharmacokinetics but had no significant association with hepatic histological end points. …
NAID 110009917753

Dioxin-Produced Alteration in the Profiles of Fecal and Urinary Metabolomes: A Change in Bile Acids and Its Relevance to Toxicity

Kakizuka Saki,Takeda Tomoki,Komiya Yukiko [他],Koba Akihiko,Uchi Hiroshi,Yamamoto Midori,Furue Masutaka,Ishii Yuji,Yamada Hideyuki
Biological and Pharmaceutical Bulletin 38(10), 1484-1495, 2015
… In addition, CYP7A1, a rate-limiting enzyme for bile acid biosynthesis, was attenuated by TCDD treatment, although TCDD induced hepatic CYP8B1, an enzyme essential for cholic acid synthesis. …
NAID 130005101584