WordNet

the 1st letter of the Roman alphabet (同)a
the blood group whose red cells carry the A antigen (同)type_A, group A
a hemoprotein composed of globin and heme that gives red blood cells their characteristic color; function primarily to transport oxygen from the lungs to the body tissues; "fish have simpler hemoglobin than mammals" (同)haemoglobin, Hb

PrepTutorEJDIC

answer / ampere
ヘモグロビン,血色素

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/06 19:12:00」(JST)

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Hemoglobin A2 (HbA₂) is a normal variant of hemoglobin A that consists of two alpha and two delta chains (α₂δ₂) and is found at low levels in normal human blood. Hemoglobin A2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene.

HbA2 exists in small amounts in all adult humans (1.5-3.1% of all hemoglobin molecules) and is increased in people with Sickle-cell disease.^[1] Its biological importance is not yet known.

References

^ "Clinical Practice Guideline for Sickle Cell Disease/Trait". American Society of Aerospace Medicine Specialists. Retrieved 3 May 2013.

External links

Hemoglobin A2 at the US National Library of Medicine Medical Subject Headings (MeSH)

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UpToDate Contents

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1. 正常ヒトヘモグロビンの構造および機能 structure and function of normal human hemoglobins
2. サラセミアの臨床症状および診断 clinical manifestations and diagnosis of the thalassemias
3. 異常ヘモグロビン症の検査室診断 laboratory diagnosis of the hemoglobinopathies
4. 不安定ヘモグロビン変異体 unstable hemoglobin variants
5. 鎌状細胞貧血における臨床的ばらつき clinical variability in sickle cell anemia

English Journal

A Novel Heme Pocket Hemoglobin Variant Associated with Normal Hematology: Hb Zara or α91(FG3)Leu→Ile (α2) (HBA2: c.274C > A).

Trova S1, Mereu P, Decandia L, Cocco E, Masala B, Manca L, Pirastru M.
Hemoglobin.Hemoglobin.2015 Aug 17:1-3. [Epub ahead of print]
We report a new hemoglobin (Hb) variant on the HBA2 gene, Hb Zara [α91(FG3)Leu→Ile (α2); HBA2: c.274C > A], which was found in a Caucasian man from Croatia. It was observed by routine cation exchange chromatography as an abnormal 21.8% fraction overlapping Hb A2, and associated with norma
PMID 26291971

A Novel Heme Pocket Hemoglobin Variant Associated with Normal Hematology: Hb Zara or α91(FG3)Leu→Ile (α2) (HBA2: c.274C > A).

Trova S1, Mereu P, Decandia L, Cocco E, Masala B, Manca L, Pirastru M.
Hemoglobin.Hemoglobin.2015 Aug 13:1-3. [Epub ahead of print]
We report a new hemoglobin (Hb) variant on the HBA2 gene, Hb Zara [α91(FG3)Leu→Ile (α2); HBA2: c.274C > A], which was found in a Caucasian man from Croatia. It was observed by routine cation exchange chromatography as an abnormal 21.8% fraction overlapping Hb A2, and associated with norma
PMID 26270736

Hb G-Waimanalo [A1] or α64(E13)Asp→Asn (α1) (HBA1: c.193G>A) Observed in a Bulgarian Family.

Petkov G1, Dimishkovska M, Tsoneva Ivanova V, Yordanov G, Zdraveski A, Plaseska-Karanfilska D.
Hemoglobin.Hemoglobin.2015 Jul 30:1-2. [Epub ahead of print]
The abnormal hemoglobin (Hb) with an aspartic acid to asparagine substitution at α64 has been found on both the α2- and α1-globin genes. It has been described in many different populations under different names, but never in Bulgaria. Using the recently proposed nomenclature, Hb G-Waimanalo [A1]
PMID 26212674

Japanese Journal

胃潰瘍の出血により急性高心拍出量性心不全を呈した高齢者大球性貧血の1例

松崎弦,芦田映直,赤沼真夫,藤井潤,世古義規
日本老年医学会雑誌 50(3), 409-412, 2013
… た．胃出血によるタール便はあったが平常の生活を送っており，その6日後の血液検査でHb 8.4 g/dl，MCV 103 flの大球性貧血が発見され翌日入院となった．入院時の胃内視鏡検査では出血を認めなかったが活動期（A2期）であり，貧血は胃潰瘍からの出血によるものと診断した．また軽度の下腿浮腫と両肺野に少量の胸水貯留があり，心エコー上著明な左室拡張障害はなく心機能は正常であったため急性高心拍出量性心不全 …
NAID 130004485882

1A2-O10 光トポグラフィを用いた歩行訓練に対する意欲の定量化(看護とメカトロニクス)

中島康貴,脇村玲衣,渡辺広樹,關雅俊,渡邉峰生,小林洋,藤江正克
ロボティクス・メカトロニクス講演会講演概要集 2012, "1A2-O10(1)"-"1A2-O10(3)", 2012-05-27
… Then, in this study, by measuring the hemoglobin concentration of the blood in prefrontal region of someone's brain with the optical topography, we proposed the method to quantify the motivation of the patient during the gait training. … In this experimental result, it is found that we showed that the types of short-term goals will be significantly higher about the hemoglobin concentration of the blood in prefrontal region of someone's brain than those of long-term goal. …
NAID 110009907575