Sodium-mediated plateau potentials in lumbar motoneurons of neonatal rats.
Bouhadfane M1, Tazerart S, Moqrich A, Vinay L, Brocard F.
The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2013 Sep 25;33(39):15626-41. doi: 10.1523/JNEUROSCI.1483-13.2013.
The development and the ionic nature of bistable behavior in lumbar motoneurons were investigated in rats. One week after birth, almost all (∼80%) ankle extensor motoneurons recorded in whole-cell configuration displayed self-sustained spiking in response to a brief depolarization that emerged whe
Functional characterization of SdcF from Bacillus licheniformis, a homolog of the SLC13 Na⁺/dicarboxylate transporters.
Pajor AM1, Sun NN, Leung A.
The Journal of membrane biology.J Membr Biol.2013 Sep;246(9):705-15. doi: 10.1007/s00232-013-9590-3. Epub 2013 Aug 25.
The SdcF transporter from Bacillus licheniformis (gene BL02343) is a member of the divalent anion sodium symporter (DASS)/SLC13 family that includes Na⁺/dicarboxylate transporters from bacteria to humans. SdcF was functionally expressed in Escherichia coli (BL21) and assayed in right side out memb
Store-operated calcium entry induced by activation of Gq-coupled alpha1B adrenergic receptor in human osteoblast.
Kodama D1, Togari A.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2013 Jul 26;437(2):239-44. doi: 10.1016/j.bbrc.2013.06.047. Epub 2013 Jun 24.
Recent studies have revealed that the sympathetic nervous system is involved in bone metabolism. We previously reported that noradrenaline (NA) suppressed K(+) currents via Gi/o protein-coupled alpha1B-adrenergic receptor (α1B-AR) in human osteoblast SaM-1 cells. Additionally, it has been demonstra
… By the innactivation of C1-inhibitor, using its blocking reagent, flufenamate, normal plasma showed an increase in fibrinolysis. … (2) In vivo: At the point of view that C1-inhibitor regulates the intrinsic fibrinolysis, flufenamate was administrated in three healthy subjects. …
… A sensitive method for the determination of four anthranilic acid derivatives (diclofenac sodium, aluminium flufenamate, mefenamic acid and tolfenamic acid) of analgesic and antiinflammatory drugs was developed by using high performance liquid chromatography (HPLC). …
The IUPHAR/BPS Guide to Pharmacology. flufenamate ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs. ... Calculated Physico-chemical Properties Hydrogen bond ...
Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on 'small' chemical compounds. ... ChEBI Name flufenamate ChEBI ID CHEBI:520819