WordNet

the 2nd letter of the Roman alphabet (同)b
the blood group whose red cells carry the B antigen (同)type_B, group B
peptide released from the amino end of fibrinogen by the action of thrombin to form fibrin during clotting of the blood

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1. フィブリノゲンの異常 disorders of fibrinogen
2. 幼児および小児における播種性血管内凝固 disseminated intravascular coagulation in infants and children
3. 血管内皮機能および血栓溶解療法の基本的メカニズム vascular endothelial function and fundamental mechanisms of fibrinolysis thrombolysis
4. 出血性素因を有する成人患者へのアプローチ approach to the adult patient with a bleeding diathesis
5. 出血症状を有する小児に対するアプローチ approach to the child with bleeding symptoms

Computer simulations of sample preconcentration in carrier-free systems and isoelectric focusing in microchannels using simple ampholytes.

Mikkonen S1, Thormann W2, Emmer Å1.
Electrophoresis.Electrophoresis.2015 Oct;36(19):2386-95. doi: 10.1002/elps.201500120. Epub 2015 Aug 3.
In this work, electrophoretic preconcentration of protein and peptide samples in microchannels was studied theoretically using the 1D dynamic simulator GENTRANS, and experimentally combined with MS. In all configurations studied, the sample was uniformly distributed throughout the channel before pow
PMID 26036978

Simple setup for gas-phase H/D exchange mass spectrometry coupled to electron transfer dissociation and ion mobility for analysis of polypeptide structure on a liquid chromatographic time scale.

Mistarz UH1, Brown JM, Haselmann KF, Rand KD.
Analytical chemistry.Anal Chem.2014 Dec 2;86(23):11868-76. doi: 10.1021/ac5035456. Epub 2014 Nov 20.
Gas-phase hydrogen/deuterium exchange (HDX) is a fast and sensitive, yet unharnessed analytical approach for providing information on the structural properties of biomolecules, in a complementary manner to mass analysis. Here, we describe a simple setup for ND3-mediated millisecond gas-phase HDX ins
PMID 25375223

Proteomic study of pilocytic astrocytoma pediatric brain tumor intracystic fluid.

Inserra I1, Iavarone F, Martelli C, D'Angelo L, Delfino D, Rossetti DV, Tamburrini G, Massimi L, Caldarelli M, Di Rocco C, Messana I, Castagnola M, Desiderio C.
Journal of proteome research.J Proteome Res.2014 Nov 7;13(11):4594-606. doi: 10.1021/pr500806k. Epub 2014 Sep 25.
Liquid chromatography in coupling with high-resolution ESI-LTQ-Orbitrap mass spectrometry was applied for a proteomic study of pediatric pilocytic astrocytoma brain tumor intracystic fluid by an integrated top-down/bottom-up platform. Both of the proteomic strategies resulted complementary and suppo
PMID 25254300

Fibrinopeptide A release is necessary for effective B:b interactions in polymerisation of variant fibrinogens with impaired A:a interactions

Soya Keisuke,Terasawa Fumiko,Okumura Nobuo
THROMBOSIS AND HAEMOSTASIS 109(2), 221-228, 2013-02
… To determine whether recombinant variant fibrinogens with no release of fibrinopeptide A (FpA) polymerise similarly to gamma D364H-fibrinoge, we examined two variant fibrinogens with substitutions altering knob 'A', A alpha 17A- and A alpha 17C-fibrinogen. … We examined thrombin- or batroxobin-catalysed fibrinopeptide release by HPLC, fibrin clot formation by turbidity and fibrin clot structure by scanning electron microscopy (SEM) and compared the results of the variants with those for gamma D364H-fibrinogen. …
NAID 120005353693