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English Journal

Modulation of colonic inflammation in Mdr1a-/- mice by green tea polyphenols and their effects on the colon transcriptome and proteome.

Barnett MP, Cooney JM, Dommels YE, Nones K, Brewster DT, Park Z, Butts CA, McNabb WC, Laing WA, Roy NC.SourceFood Nutrition and Health Team, Food and Bio-based Products Group, Palmerston North 4442, New Zealand. Electronic address: matthew.barnett@agresearch.co.nz.
The Journal of nutritional biochemistry.J Nutr Biochem.2013 May 2. pii: S0955-2863(13)00045-4. doi: 10.1016/j.jnutbio.2013.02.007. [Epub ahead of print]
Animal models are an important tool to understand the complex pathogenesis of inflammatory bowel diseases (IBDs). This study tested the anti-inflammatory potential of a green tea extract rich in polyphenols (GrTP) in the colon of the multidrug resistance targeted mutation (Mdr1a-/-) mouse model of I
PMID 23643524

Bulk physicochemical, interconnectivity, and mechanical properties of calcium phosphate cements-fibrin glue composites for bone substitute applications.

Lopez-Heredia MA, Pattipeilohy J, Hsu S, Grykien M, van der Weijden B, Leeuwenburgh SC, Salmon P, Wolke JG, Jansen JA.SourceDepartment of Biomaterials, College of Dental Science, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.
Journal of biomedical materials research. Part A.J Biomed Mater Res A.2013 Feb;101(2):478-90. doi: 10.1002/jbm.a.34342. Epub 2012 Aug 28.
Calcium phosphate cements (CPCs) and fibrin glue (FG) are used for surgical applications. Their combination is promising to create bone substitutes able to promote cell attachment and bone remodeling. This study proposes a novel approach to create CPC-FG composites by simultaneous CPC setting and FG
PMID 22927324

Reactive carbonyl compounds (RCCs) cause aggregation and dysfunction of fibrinogen.

Xu YJ, Qiang M, Zhang JL, Liu Y, He RQ.SourceState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Protein & cell.Protein Cell.2012 Aug;3(8):627-40. doi: 10.1007/s13238-012-2057-y. Epub 2012 Jul 26.
Fibrinogen is a key protein involved in coagulation and its deposition on blood vessel walls plays an important role in the pathology of atherosclerosis. Although the causes of fibrinogen (fibrin) deposition have been studied in depth, little is known about the relationship between fibrinogen deposi
PMID 22836718