WordNet

a poisonous substance produced during the metabolism and growth of certain microorganisms and some higher plant and animal species

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/16 17:30:12」(JST)

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1. 美容適応としてのボツリヌス毒素投与の概要 overview of botulinum toxin for cosmetic indications
2. 小児における志賀毒素産生性大腸菌（STEC）溶血性尿毒症症候群（HUS）の治療および予後 treatment and prognosis of shiga toxin producing escherichia coli stec hemolytic uremic syndrome hus in children
3. 美容適応としてのボツリヌス毒素：特定部位治療 botulinum toxin for cosmetic indications treatment of specific sites
4. 非神経性の下部尿路症状の治療におけるボツリヌス毒素の使用 use of botulinum toxin for treatment of non neurogenic lower urinary tract conditions
5. 連鎖球菌扁桃咽頭炎の合併症 complications of streptococcal tonsillopharyngitis

Arzanlou M1.
Microbial pathogenesis.Microb Pathog.2016 Apr;93:166-71. doi: 10.1016/j.micpath.2016.02.010. Epub 2016 Feb 18.
Streptococcal pyrogenic exotoxin B (SpeB) is an important virulence factor of group A streptococci (GAS) and inactivation of SpeB results in the significantly decreased virulence of the bacterium. The protein is secreted as an inactive zymogen of 40 KDa (SpeBz) and undergoes proteolytic truncation t
PMID 26911644

The majority of 9,729 group A streptococcus strains causing disease secrete SpeB cysteine protease: pathogenesis implications.

Olsen RJ1, Raghuram A2, Cantu C2, Hartman MH2, Jimenez FE2, Lee S2, Ngo A2, Rice KA2, Saddington D2, Spillman H2, Valson C2, Flores AR3, Beres SB2, Long SW2, Nasser W2, Musser JM2.
Infection and immunity.Infect Immun.2015 Dec;83(12):4750-8. doi: 10.1128/IAI.00989-15. Epub 2015 Sep 28.
Group A streptococcus (GAS), the causative agent of pharyngitis and necrotizing fasciitis, secretes the potent cysteine protease SpeB. Several lines of evidence suggest that SpeB is an important virulence factor. SpeB is expressed in human infections, protects mice from lethal challenge when used as
PMID 26416912

Proteolytic processing of the streptococcal IgG endopeptidase IdeS modulates the functional properties of the enzyme and results in reduced immunorecognition.

Persson H1, Söderberg JJ1, Vindebro R1, Johansson BP2, von Pawel-Rammingen U3.
Molecular immunology.Mol Immunol.2015 Dec;68(2 Pt A):176-84. doi: 10.1016/j.molimm.2015.07.014. Epub 2015 Sep 3.
The important human gram positive bacterial pathogen Streptococcus pyogenes employs various virulence factors to promote inflammation and to facilitate invasive disease progression. In this study we explored the relation of the secreted streptococcal cysteine proteases IdeS and SpeB, and neutrophil
PMID 26343448