English Journal
- Prophylactic effect of egualen sodium, a stable azulene derivative, on gastrointestinal damage induced by ischemia/reperfusion, double antiplatelet therapy and loxoprofen in rats.
- Amagase K1, Yoshida Y, Hara D, Murakami T, Takeuchi K.
- Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.J Physiol Pharmacol.2013 Feb;64(1):65-75.
- We examined the effect of egualen, a stable azulene derivative, against gastric damage induced by ischemia/reperfusion (I/R), gastric bleeding induced by double antiplatelet therapy with aspirin (ASA) plus clopidogrel, and small intestinal damage generated by loxoprofen, and investigated the possibl
- PMID 23568973
- A ring expansion-annulation strategy for the synthesis of substituted azulenes. Preparation and Suzuki coupling reactions of 1-azulenyl triflates.
- Kane JL Jr1, Shea KM, Crombie AL, Danheiser RL.
- Organic letters.Org Lett.2001 Apr 5;3(7):1081-4.
- [structure: see text]. A new strategy for the synthesis of substituted azulenes is reported, based on the reaction of beta'-bromo-alpha-diazo ketones with rhodium carboxylates. The key transformation involves intramolecular addition of a rhodium carbenoid to an arene pi-bond, electrocyclic ring open
- PMID 11277800
- Inhibitory effect of egualen sodium: a new stable derivative of azulene on histamine release from mast cell-like cells in the stomach.
- Akagi M1, Matsui N, Mochizuki S, Tasaka K.
- Pharmacology.Pharmacology.2001;63(4):203-9.
- We studied the inhibitory effect of egualen sodium (ES) (sodium 3-ethyl-7-isopropyl-1-azulenesulfonate 1/3 hydrate, KT1-32), a new derivative and more stable compound than azulene, on histamine release from the mucosal histaminocytes and elucidated the mechanism for this action. ES prevented the his
- PMID 11729358
Japanese Journal
- エグアレンのNSAID小腸粘膜傷害, 虚血再灌流胃粘膜傷害およびクロピドグレル/塩酸アスピリンによる胃出血に対する効果
- 竹内 孝治
- 潰瘍 = Ulcer research 39(1), 5-8, 2012-05-20
- NAID 10030578536
- エグアレンナトリウム(アズロキサ^【○!R】錠・顆粒)の小腸損傷抑制作用機序
- 野々山 兼市
- 潰瘍 = Ulcer research 39(1), 1-4, 2012-05-20
- NAID 10030578529
- アスピリン誘起ラット小腸傷害に対する胃粘膜防御薬エグアレンナトリウムの効果
- 野々山 兼市,岡部 進
- 潰瘍 = Ulcer research 37(1), 97-102, 2010-05-20
- NAID 10027081522
Related Links
- Egualen is a medicine available in a number of countries worldwide. A list of US medications equivalent to Egualen is available on the Drugs.com website. ... Scheme Rec.INN CAS registry number (Chemical Abstracts Service)
- Egualen Sodium Granules Dissolution <6.10> Weigh accurately an amount of Egualen Sodium Granules, equivalent to about 5 mg of egualen sodium (C15H17NaO3S·1/3 H2O) according to the labeled amount, and perform the test at ...
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