WordNet

spread out; not concentrated in one place; "a large diffuse organization"
move outward; "The soldiers fanned out" (同)spread, spread out, fan out
lacking conciseness; "a diffuse historical novel"
of or relating to interstices
development of excess fibrous connective tissue in an organ
(of light rays) subjected to scattering by reflection from a rough surface or transmission through a translucent material; "diffused light"

PrepTutorEJDIC

〈光・熱・液体など〉‘を'散らす,放散する,拡散させる / 〈学問・知識など〉‘を'広める,普及させる / 散る,放散する,拡散する / 広まる,普及する / 広く散った,広がった / 〈文体などが〉締まりのない,散漫な
線維症(線維性結合線維が増殖し過ぎる症状)
肺の;肺を冒す

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1. 特発性肺線維症の治療 treatment of idiopathic pulmonary fibrosis
2. 特発性肺線維症の病因 pathogenesis of idiopathic pulmonary fibrosis
3. 間質性肺疾患を有する成人に対するアプローチ：臨床的評価 approach to the adult with interstitial lung disease clinical evaluation
4. 間質性肺疾患を有する成人に対するアプローチ：診断的検査 approach to the adult with interstitial lung disease diagnostic testing
5. 特発性間質性肺炎：臨床症状および病理 idiopathic interstitial pneumonias clinical manifestations and pathology

Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis models.

Yu W1, Guo F2, Song X3.
Pharmaceutical biology.Pharm Biol.2017 Dec;55(1):450-455.
CONTEXT: Previous studies have reported that caveolin-1 (Cav-1) is associated with lung fibrosis. However, the role of Cav-1 expression in pirfenidone-treated idiopathic pulmonary fibrosis (IPF) is unknown.OBJECTIVE: This study investigated Cav-1 expression in pirfenidone-treated IPF, and compared t
PMID 27937011

MnTBAP Inhibits Bleomycin-Induced Pulmonary Fibrosis by Regulating VEGF and Wnt Signaling.

Venkatadri R1, Iyer AK1, Ramesh V2, Wright C1, Castro CA3, Yakisich JS1, Azad N1.
Journal of cellular physiology.J Cell Physiol.2017 Mar;232(3):506-516. doi: 10.1002/jcp.25608. Epub 2016 Sep 26.
Cellular oxidative stress is implicated not only in lung injury but also in contributing to the development of pulmonary fibrosis. We demonstrate that a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger, manganese (III) tetrakis (4-benzoic acid) porphyrin chloride (MnTBAP
PMID 27649046

In vitro inflammatory effects of polyhexamethylene biguanide through NF-κB activation in A549 cells.

Kim HR1, Shin DY2, Chung KH3.
Toxicology in vitro : an international journal published in association with BIBRA.Toxicol In Vitro.2017 Feb;38:1-7. doi: 10.1016/j.tiv.2016.10.006. Epub 2016 Oct 13.
Polyhexamethylene biguanide (PHMB) is a member of the polymeric guanidine family, which is used as a biocide and preservative in industrial, medicinal, and consumer products. Some studies reported that polyhexamethylene guanidine phosphate, which is also a member of the guanidine family, induced sev
PMID 27746371

Osthole alleviates bleomycin-induced pulmonary fibrosis via modulating angiotensin-converting enzyme 2/angiotensin-(1-7) axis and decreasing inflammation responses in rats