Δ6不飽和化酵素
- 関
- linoleoyl-CoA desaturase
WordNet
- an object shaped like an equilateral triangle
- a low triangular area of alluvial deposits where a river divides before entering a larger body of water; "the Mississippi River delta"; "the Nile delta"
- the 4th letter of the Greek alphabet
PrepTutorEJDIC
- デルタ(ギリシア語アルファベットの第4字Δ,δ;英語D,dに相当) / (河口の)三角州,デルタ / 三角形をしたもの
UpToDate Contents
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English Journal
- The metabolic cascade leading to eicosanoid precursors - desaturases, elongases, and phospholipases A(2) - is altered in Zucker fatty rats.
- Fevre C, Bellenger S, Pierre AS, Minville M, Bellenger J, Gresti J, Rialland M, Narce M, Tessier C.AbstractMetabolic syndrome characterized by insulin resistance and obesity is accompanied by severe lipid metabolism perturbations and chronic low-grade inflammation. However, many unresolved questions remained regarding the regulation that underlie dyslipidemia, particularly the regulation of the metabolic cascade (synthesis and release) leading to eicosanoid precursors release. This study was undertaken to investigate the regulation of desaturases/elongases and phospholipases A(2) during the establishment of metabolic syndrome. Our results showed that delta-6 desaturase as well as elongase-6 expressions were upregulated in 3-month-old Zucker fatty rats as compared to lean littermates, independently of SREBP-1c activation. We also demonstrated for the first time an increase of liver group VII phospholipase A(2) gene expression in the obese animals together with a strong specific inhibition of type IVA and VIA phospholipases A(2). These results suggest that the regulation of unsaturated fatty acids biosynthesis and signalling cascade could contribute to the development of liver lipid dysregulation related to metabolic syndrome and may be considered as new potential targets in such pathological conditions.
- Biochimica et biophysica acta.2011 Jun;1811(6):409-17. Epub 2010 Dec 21.
- Metabolic syndrome characterized by insulin resistance and obesity is accompanied by severe lipid metabolism perturbations and chronic low-grade inflammation. However, many unresolved questions remained regarding the regulation that underlie dyslipidemia, particularly the regulation of the metabolic
- PMID 21172452
- Functional characterization of a delta 6-desaturase gene from the black seabream (Acanthopagrus schlegeli).
- Kim SH, Kim JB, Kim SY, Roh KH, Kim HU, Lee KR, Jang YS, Kwon M, Park JS.SourceNational Academy of Agricultural Science, Rural Development Administration, Seodun-Dong, Suwon, 441-707, Korea, sunheekim00@korea.kr.
- Biotechnology letters.2011 Jun;33(6):1185-93. Epub 2011 Feb 12.
- Delta 6-fatty acid desaturase (D6DES) is used in the synthesis of polyunsaturated fatty acids (PUFAs) from microorganisms to higher animals, including arachidonic acid (ARA) and eicosapentaenoic acid (EPA). A 1,338?bp full-length cDNA encoding D6DES was cloned from Acanthopagrus schlegeli (AsD6DES)
- PMID 21318631
Japanese Journal
- Identification of a heat shock-responsive cis-acting DNA sequence and its transcriptional regulator : Their roles in the expression of the Spirulina-desD gene in response to heat stress(GENETICS, MOLECULAR BIOLOGY, AND GENE EXPRESSION)
- Kurdrid Pavinee,Phuengcharoen Phuttawadee,Cheevadhanarak Supapon,Tanticharoen Morakot,Hongsthong Apiradee
- Journal of bioscience and bioengineering 109(3), 205-210, 2010-03
- This study addresses the importance of a heat-shock-responsive cis-acting DNA element and its transcriptional regulator, which play key roles in the regulation of the Spirulina-desD gene on exposure t …
- NAID 110007612423
- The Metabolism and Distribution of Docosapentaenoic Acid (n-6) in the Liver and Testis of Growing Rats
- TAM Phyllis S. Y.,SAWADA Rumi,CUI Yan,MATSUMOTO Akiyo,FUJIWARA Yoko
- Bioscience, Biotechnology, and Biochemistry 72(10), 2548-2554, 2008
- … To investigate the metabolism and distribution of docosapentaenoic acid (22:5n-6, DPA) in the liver and testis of growing rats, 22:5n-6 was administered to their dams. … Newborn rats with a low hepatic arachidonic acid (20:4n-6, AA) level were generated by administrating a diet rich in docosahexaenoic acid (22:6n-3, DHA) but n-6 fatty acid (FA) free to pregnant dams. …
- NAID 130000408276
Related Links
- Gamme de compléments alimentaires Delta 6 Desaturase élaborée par Elke AROD. Garanti sans gluten et sans produit laitier.
- 1. Annu Rev Nutr. 2004;24:345-76. Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases. Nakamura MT(1), Nara TY. Author information: (1)Department of Food Science and Human ...
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★リンクテーブル★
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- 英
- delta-6-desaturase
- 関
- リノレオイルCoA不飽和化酵素
[★]
- 関
- delta-6-desaturase
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不飽和化酵素、脱飽和酵素、デサチュラーゼ
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δ、デルタ