脱ユビキチン化酵素
WordNet
- a legal document signed and sealed and delivered to effect a transfer of property and to show the legal right to possess it; "he signed the deed"; "he kept the title to his car in the glove compartment" (同)deed of conveyance, title
- go `ding dong, like a bell (同)dong, dingdong
- a ringing sound
- any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
PrepTutorEJDIC
- 『行為』,行動 / (正式の)捺印証書,権利書 / …'を'証書を作製して譲渡する
- 〈鐘など〉‘を'ガンガン鳴らす / 〈鐘などが〉ガンガン鳴る / (鐘の)ガンガン鳴る音
- 酵素
- (おもに人称代名詞・固有名詞(人名),thereの後で)had, wouldの短縮形 / (疑問文でwhere,what,whenの後で)didの短縮形;Where'd he go?=Where did he go?
- Delaware
UpToDate Contents
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English Journal
- UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 ubiquitinylation.
- Hans F1, Fiesel FC2, Strong JC1, Jäckel S1, Rasse TM1, Geisler S1, Springer W2, Schulz JB3, Voigt A3, Kahle PJ4.
- The Journal of biological chemistry.J Biol Chem.2014 May 13. pii: jbc.M114.561704. [Epub ahead of print]
- TDP-43 characterizes insoluble protein aggregates in distinct subtypes of frontotemporal lobar degeneration (FTLD-TDP) and amyotrophic lateral sclerosis (ALS). TDP-43 mediates many RNA processing steps within distinct protein complexes. Here we identify novel TDP-43 protein interactors in a yeast 2-
- PMID 24825905
- Mechanism of the Rpn13-induced activation of Uch37.
- Jiao L1, Ouyang S, Shaw N, Song G, Feng Y, Niu F, Qiu W, Zhu H, Hung LW, Zuo X, Eleonora Shtykova V, Zhu P, Dong YH, Xu R, Liu ZJ.
- Protein & cell.Protein Cell.2014 Apr 22. [Epub ahead of print]
- Uch37 is a de-ubiquitinating enzyme that is activated by Rpn13 and involved in the proteasomal degradation of proteins. The full-length Uch37 was shown to exhibit low iso-peptidase activity and is thought to be auto-inhibited. Structural comparisons revealed that within a homo-dimer of Uch37, each o
- PMID 24752541
- Ubpy controls the stability of the ESCRT-0 subunit Hrs in development.
- Zhang J1, Du J, Lei C, Liu M, Zhu AJ.
- Development (Cambridge, England).Development.2014 Apr;141(7):1473-9. doi: 10.1242/dev.099564. Epub 2014 Feb 26.
- Ubiquitylated developmental membrane signaling proteins are often internalized for endocytic trafficking, through which endosomal sorting complexes required for transport (ESCRT) act sequentially to deliver internalized cargos to lysosomes. The ESCRT function in endocytic sorting is well established
- PMID 24574010
Japanese Journal
- Ubiquitin-proteasome系と神経変性
Related Links
- 1. EMBO J. 2012 Oct 3;31(19):3918-34. doi: 10.1038/emboj.2012.232. Epub 2012 Aug 21. The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response. Butler LR, Densham RM, Jia J, Garvin AJ ...
- Short Report The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein Lauren M DeSalle 1, Esther Latres 1, Douglas Lin 2, Edgard Graner 2, Alessia Montagnoli 1, Rohan T Baker 4, Michele Pagano 1 and Massimo Loda ...
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- 英
- de-ubiquitinating enzyme
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