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present at birth but not necessarily hereditary; acquired during fetal development (同)inborn, innate

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1. 先天性肺気道奇形の出生前診断およびマネージメント prenatal diagnosis and management of congenital pulmonary airway malformation
2. 先天性および小児冠動脈異常 congenital and pediatric coronary artery abnormalities
3. 先天性肺気道（嚢胞性腺腫様）形成異常 congenital pulmonary airway cystic adenomatoid malformation
4. 下顎、口、口腔、および咽頭の先天異常 congenital anomalies of the jaw mouth oral cavity and pharynx
5. 先天梅毒：臨床的特徴および診断 congenital syphilis clinical features and diagnosis

Hereditary hypotransferrinemia can lead to elevated transferrin saturation and, when associated to HFE or HAMP mutations, to iron overload.

Beaumont-Epinette MP1, Delobel JB2, Ropert M3, Deugnier Y4, Loréal O5, Jouanolle AM1, Brissot P6, Bardou-Jacquet E6.
Blood cells, molecules & diseases.Blood Cells Mol Dis.2015 Feb;54(2):151-4. doi: 10.1016/j.bcmd.2014.11.020. Epub 2014 Nov 26.
As our understanding of iron metabolism improves through the more accurate description of iron metabolism actors, new causes of iron overload are identified. We, here, report 16 cases of hereditary hypotransferrinemia related to 4 previously undescribed TF (transferrin) mutations (p.Val221Gly, p.Arg
PMID 25486930

Hepatocyte divalent metal-ion transporter-1 is dispensable for hepatic iron accumulation and non-transferrin-bound iron uptake in mice.

Wang CY1, Knutson MD.
Hepatology (Baltimore, Md.).Hepatology.2013 Aug;58(2):788-98. doi: 10.1002/hep.26401. Epub 2013 Jul 1.
Divalent metal-ion transporter-1 (DMT1) is required for iron uptake by the intestine and developing erythroid cells. DMT1 is also present in the liver, where it has been implicated in the uptake of transferrin-bound iron (TBI) and non-transferrin-bound iron (NTBI), which appears in the plasma during
PMID 23508576

Bartnikas TB1.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.Biometals.2012 Aug;25(4):677-86. doi: 10.1007/s10534-012-9520-3.
Transferrin is an abundant serum metal-binding protein best known for its role in iron delivery. The human disease congenital atransferrinemia and animal models of this disease highlight the essential role of transferrin in erythropoiesis and iron metabolism. Patients and mice deficient in transferr
PMID 22294463