WordNet
- drive (a vessel) ashore
- line consisting of a complex of fibers or filaments that are twisted together to form a thread or a rope or a cable
- a pattern forming a unity within a larger structural whole; "he tried to pick up the strands of his former life"; "I could hear several melodic strands simultaneously"
- a poetic term for a shore (as the area periodically covered and uncovered by the tides)
- a street in west central London famous for its theaters and hotels
PrepTutorEJDIC
- 〈船〉‘を'座礁させる / 《受動態で》〈人〉‘を'置き去りにする,困った状態におく / 〈船が〉座礁する / 〈人が〉途方に暮れる,立ち往生する / 岸,浜
- こ撚(よ)り(何本かより合わせて糸・なわなどにするその一本) / (より合わせた)糸,ひも;(頭髪の)房 / (真珠・ビーズなど)ひもに通したもの
- 窮した,行き詰まった,こんがらがった
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/16 21:21:35」(JST)
[Wiki en表示]
When referring to DNA transcription, the coding strand is the DNA strand which has the same base sequence as the RNA transcript produced (although with thymine replaced by uracil). It is this strand which contains codons, while the non-coding strand contains anti-codons. During transcription, RNA Pol II binds the non-coding strand, reads the anti-codons, and transcribes their sequence to synthesize an RNA transcript with complementary bases. By convention, the coding strand is the strand used when displaying a DNA sequence. It is presented in the 5' to 3' direction.
Contents
- 1 Alternative terms for strands
- 2 Strands in transcription bubble
- 3 RNA-DNA hybrid
- 4 References
- 5 Bibliography
Alternative terms for strands
Wherever a gene exists on a DNA molecule, one strand is the coding strand (or sense strand or non-template strand), and the other is the noncoding strand (also called the antisense strand,[1] anticoding strand, template strand, or transcribed strand).
Strands in transcription bubble
During transcription, RNA polymerase unwinds a short section of the DNA double helix near the start of the gene (the transcription start site). This unwound section is known as the transcription bubble. The RNA polymerase, and with it the transcription bubble, travels along the noncoding strand in the opposite, 3' to 5', direction, as well as polymerizing a newly synthesized strand in 5' to 3' or downstream direction. The DNA double helix is rewound by RNA polymerase at the rear of the transcription bubble (Lewin, pp 235 [1]). Like how two adjacent zippers work, when pulled together, they unzip and rezip as they proceed in a particular direction.
RNA-DNA hybrid
Where the helix is unwound, the coding strand consists of unpaired bases, while the template strand consists of an RNA:DNA composite, followed by a number of unpaired bases at the rear. This hybrid consists of the most recently added nucleotides of the RNA transcript, complementary base-paired to the template strand. The number of base-pairs in the hybrid is under investigation, but it has been suggested that the hybrid is formed from the last 10 nucleotides added.[2]
References
- ^ a b Lewin, Benjamin (2008). Genes IX. Oxford University Press. p. 129. ISBN 978-0-7637-4063-4.
- ^ Griffiths 2005, pp. 259–265
Bibliography
- Griffiths, A.J.F. et al. (2005). Introduction to Genetic Analysis (8th ed.). W.H. Freeman. ISBN 0-7167-4939-4.
- Lewin, B. (2000). Genes VII. New York: Oxford University Press. ISBN 0-19-879277-8.
UpToDate Contents
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English Journal
- cis-Acting RNA elements in the hepatitis C virus RNA genome.
- Sagan SM1, Chahal J1, Sarnow P2.
- Virus research.Virus Res.2015 Aug 3;206:90-8. doi: 10.1016/j.virusres.2014.12.029. Epub 2015 Jan 7.
- Hepatitis C virus (HCV) infection is a rapidly increasing global health problem with an estimated 170 million people infected worldwide. HCV is a hepatotropic, positive-sense RNA virus of the family Flaviviridae. As a positive-sense RNA virus, the HCV genome itself must serve as a template for trans
- PMID 25576644
- A 57-bp deletion in the ovine KAP6-1 gene affects wool fibre diameter.
- Zhou H1,2, Gong H2, Li S1, Luo Y1, Hickford JG2.
- Journal of animal breeding and genetics = Zeitschrift für Tierzüchtung und Züchtungsbiologie.J Anim Breed Genet.2015 Aug;132(4):301-7. doi: 10.1111/jbg.12138. Epub 2015 Mar 17.
- High glycine-tyrosine keratin-associated proteins (HGT-KAPs) are predominantly present in the orthocortex of wool fibres. They vary in abundance in different wools and have been implicated in regulating wool fibre properties, but little is known about the functional roles of these proteins in the fi
- PMID 25782086
Japanese Journal
- Traffic jam on the cellular secretory pathway generated by a replication protein from a plant RNA virus
- Hyodo Kiwamu,Kaido Masanori,Okuno Tetsuro
- Plant Signaling & Behavior 9(3), 2014-04-08
- … Although positive-strand RNA [(+)RNA] viruses have a limited coding capacity, they can replicate efficiently in host cells because of their ability to use host-derived proteins, membranes, lipids, and metabolites, and to rewire cellular trafficking pathways. …
- NAID 120005439155
- HTLV-1 bZIP Factor Induces Inflammation through Labile Foxp3 Expression.
- Yamamoto-Taguchi Nanae,Satou Yorifumi,Miyazato Paola,Ohshima Koichi,Nakagawa Masanori,Katagiri Koko,Kinashi Tatsuo,Matsuoka Masao
- PLoS pathogens 9(9), 2013-09-19
- … The HTLV-1 basic leucine zipper factor (HBZ) gene is encoded in the minus strand of the proviral DNA and is constitutively expressed in infected cells and ATL cells. … Consistent with this finding, the conserved non-coding sequence 2 region of the Foxp3 gene was hypermethylated in Treg cells of HBZ-Tg mice, which is a characteristic of iTreg cells. …
- NAID 120005341884
Related Links
- coding strand. See sense strand. coding strand one of the two strands of DNA that is transcribed. Called also sense strand. cod·ing strand the strand of duplex DNA that has the same sequence as the mRNA (except that mRNA ...
- Definition of coding strand (plus strand; sense strand) The strand in duplex DNA that by convention contains the same sequence of bases as that in the messenger RNA (mRNA) transcribed from the DNA (except that the RNA has ...
Related Pictures
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- sense strand、coding strand
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- 座礁させる、(岸に)打ち上げられる、(浜に)取り残される
- a 26-year-old woman is stranded for more than a week when her hiking trip is interrupted by an avalanche.
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