WordNet

medicine that prevents or retards the clotting of blood (同)anticoagulant medication, decoagulant
passing from one to another; "circulating bills and coins"

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1. 抗凝固療法関連腎症 anticoagulant related nephropathy
2. 周産期心筋症：治療および予後 peripartum cardiomyopathy treatment and prognosis
3. ワルファリンに関係した脳出血における抗凝固療法の反転 reversal of anticoagulation in warfarin associated intracerebral hemorrhage
4. 直接トロンビン阻害剤および直接Xa因子阻害剤による抗凝固療法 anticoagulation with direct thrombin inhibitors and direct factor xa inhibitors
5. 標的特異的経口抗凝固剤を投与されている患者における出血のマネージメント management of bleeding in patients receiving target specific oral anticoagulants

Impact of heparin and short term anesthesia on the quantification of cytokines in laboratory mouse plasma.

Teilmann AC1, Kalliokoski O, Jacobsen KR, Hau J, Abelson KS.
Acta veterinaria Scandinavica.Acta Vet Scand.2014 May 20;56(1):33. doi: 10.1186/1751-0147-56-33.
BACKGROUND: Studies have reported that heparin may be unsuitable as an anticoagulant in human plasma samples when quantifying cytokines using multiplex bead array assays. For mouse samples, multiplex assays have been validated for serum and EDTA-plasma, but it remains to be elucidated whether hepari
PMID 24884817

The fibrinogen γA/γ' isoform does not promote acute arterial thrombosis in mice.

Walton BL1, Getz TM, Bergmeier W, Lin FC, Uitte de Willige S, Wolberg AS.
Journal of thrombosis and haemostasis : JTH.J Thromb Haemost.2014 May;12(5):680-9. doi: 10.1111/jth.12534.
BACKGROUND: Elevated plasma fibrinogen is associated with arterial thrombosis in humans and promotes thrombosis in mice by increasing fibrin formation and thrombus fibrin content. Fibrinogen is composed of six polypeptide chains: (Aα, Bβ, and γ)2. Alternative splicing of the γ chain leads to a d
PMID 24916154

宮田茂樹,山本晴子,河野浩之,豊田一則,峰松一夫
脳神経外科ジャーナル 17(12), 909-916, 2008-12-20
ヘパリンが誘引となり血栓塞栓症を引き起こすという逆説的な現象は,ヘパリン起因性血小板減少症(HIT)として病態が解明されつつある. HITでは,血小板第4因子(PF4)とヘパリンとの複合体に対する抗体(抗PF4/heparin抗体)が,血小板,血管内皮を活性化させ,トロンビンの過剰産生を生じ,血小板減少,動静脈血栓症を誘発する.通常発症型HITは,ヘパリン投与開始後5?14日の間に発症する,抗PF …
NAID 110007007598