WordNet

quality of being easily damaged or destroyed (同)breakability, frangibleness, frangibility
lack of physical strength (同)delicacy
a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"

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Analysis of chromosome damage by sister chromatid exchange (SCE) and redox homeostasis characterization on sheep flocks from Sardinian pasturelands.

Genualdo V1, Perucatti A2, Pauciullo A3, Iannuzzi A2, Incarnato D2, Spagnuolo MS4, Solinas N5, Bullitta S6, Iannuzzi L2.
The Science of the total environment.Sci Total Environ.2015 Sep 15;527-528:393-400. doi: 10.1016/j.scitotenv.2015.05.021. Epub 2015 May 15.
Over the last decades, an increase of pollutants of diverse origin (industrial, military, mining, etc.) was recorded in several areas of Sardinia Island. We report the results of a multidisciplinary and complementary study based on cytogenetic and physiological analyses. The data obtained show the e
PMID 25984702

Understanding replication fork progression, stability, and chromosome fragility by exploiting the Suppressor of Underreplication protein.

Nordman JT1, Orr-Weaver TL1.
BioEssays : news and reviews in molecular, cellular and developmental biology.Bioessays.2015 Jun 9. doi: 10.1002/bies.201500021. [Epub ahead of print]
There are many layers of regulation governing DNA replication to ensure that genetic information is accurately transmitted from mother cell to daughter cell. While much of the control occurs at the level of origin selection and firing, less is known about how replication fork progression is controll
PMID 26059810

p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency.

Ghule PN1, Xie RL, Colby JL, Jones SN, Lian JB, van Wijnen AJ, Stein JL, Stein GS.
Cell cycle (Georgetown, Tex.).Cell Cycle.2015 Jun 1:1-8. [Epub ahead of print]
Histone Nuclear Factor P (HINFP) is essential for expression of histone H4 genes. Ablation of Hinfp and consequential depletion of histones alter nucleosome spacing and cause stalled replication and DNA damage that ultimately result in genomic instability. Faithful replication and packaging of newly
PMID 26030398

ASAKURA Nobuaki,MORI Naoki,NAKAMURA Chiharu,OHTSUKA Ichiro
Genes & genetic systems 84(3), 233-237, 2009-06-25
… The Q locus located on the long arm of chromosome 5A is a key factor in evolution and widespread cultivation of domesticated wheat. … The Q locus pleiotropically affects many agronomically important traits including threshability, glume shape and tenacity, rachis fragility and others. …
NAID 10026091079