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1. 認知症治療におけるコリンエステラーゼ阻害剤 cholinesterase inhibitors in the treatment of dementia
2. レビー小体型認知症の予後および治療 prognosis and treatment of dementia with lewy bodies
3. 認知症の治療 treatment of dementia
4. 前頭側頭型認知症：治療 frontotemporal dementia treatment
5. せん妄および急性錯乱状態：予防、治療、および予後 delirium and acute confusional states prevention treatment and prognosis

The estimation of oxime efficiency is affected by the experimental design of phosphylated acetylcholinesterase reactivation.

Maček Hrvat N1, Zorbaz T2, Šinko G3, Kovarik Z4.
Toxicology letters.Toxicol Lett.2017 Nov 24. pii: S0378-4274(17)31481-9. doi: 10.1016/j.toxlet.2017.11.022. [Epub ahead of print]
PMID 29180286

The biodistribution and pharmacokinetics of the oxime acetylcholinesterase reactivator RS194B in guinea pigs.

Malfatti MA1, Enright HA2, Be NA2, Kuhn EA2, Hok S3, McNerney MW4, Lao V2, Nguyen TH5, Lightstone FC2, Carpenter TS2, Bennion BJ2, Valdez CA3.
Chemico-biological interactions.Chem Biol Interact.2017 Nov 1;277:159-167. doi: 10.1016/j.cbi.2017.09.016. Epub 2017 Sep 21.
PMID 28941624

Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006-2016).

Gorecki L1,2, Korabecny J1,2, Musilek K2,3, Nepovimova E1,2, Malinak D2,4, Kucera T1, Dolezal R2,3, Jun D1,2, Soukup O1,2, Kuca K2,3.
Expert opinion on therapeutic patents.Expert Opin Ther Pat.2017 Sep;27(9):971-985. doi: 10.1080/13543776.2017.1338275. Epub 2017 Jun 6.
PMID 28569609

二神幸次郎 [他],藤井俊志,堀岡正義,朝倉一,深川光郎
情報管理 28(10), 873-884, 1986
… 低毒性といわれる有機リン系農薬による中毒の治療に対して, 従来使用されてきたChE(Cholinesterase)再活性化薬, PAM(Pralidoxime)が有効でなかったとする報告がある。 …
NAID 130001858281

Studies on the efficacy of diethyxime as an antidote against organophosphorus intoxication in rats.

DUBE S.N.,GHOSH A.K.,JEEVARATHINAM K.,KUMAR D.,GUPTA S. DAS,PANT B.P.,BATRA B.S.,JAISWAL D.K.
The Japanese Journal of Pharmacology 41(3), 267-271, 1986
… Diethyxime, a non-quaternary cholinesterase reactivator was evaluated for its antidotal efficacy against organophosphorus intoxication in rats using the protection index, cholinesterase reactivation and neuromuscular function as the experimental protocol. … The protective efficacy against diisopropyl fluorophosphate (DFP) poisoning was not observed with this reactivator. …
NAID 130000834514

リンク元	「コリンエステラーゼ再賦活薬」「コリンエステラーゼ再活性化薬」
関連記事	「cholinesterase」「cholinesterases」