- 関
- centrosome duplication
WordNet
- addition of extra material or illustration or clarifying detail; "a few remarks added in amplification and defense"; "an elaboration of the sketch followed" (同)elaboration
- the amount of increase in signal power or voltage or current expressed as the ratio of output to input (同)gain
- (electronics) the act of increasing voltage or power or current
- small region of cytoplasm adjacent to the nucleus; contains the centrioles and serves to organize the microtubules (同)central_body
PrepTutorEJDIC
- 拡大,拡張,増大 / (電気の)増幅;(レンズの)倍率
UpToDate Contents
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English Journal
- Gastric Cancer Patients with High PLK1 Expression and DNA Aneuploidy Correlate with Poor Prognosis.
- Otsu H, Iimori M, Ando K, Saeki H, Aishima S, Oda Y, Morita M, Matsuo K, Kitao H, Oki E, Maehara Y.
- Oncology.Oncology.2016 Jun 2. [Epub ahead of print]
- Gastric cancer is the fourth most common cancer worldwide. Although it is important to identify patients at high risk for a poor outcome, factors correlating with prognosis in gastric cancer are largely unknown. Here, we focus on the correlations among expression of Polo-like kinase 1 (PLK1), DNA pl
- PMID 27245623
- 14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression.
- Mukhopadhyay A1, Sehgal L1, Bose A1, Gulvady A1, Senapati P2, Thorat R1, Basu S1, Bhatt K1, Hosing AS1, Balyan R3, Borde L4, Kundu TK2, Dalal SN1.
- Scientific reports.Sci Rep.2016 Jun 2;6:26580. doi: 10.1038/srep26580.
- More than 80% of malignant tumors show centrosome amplification and clustering. Centrosome amplification results from aberrations in the centrosome duplication cycle, which is strictly coordinated with DNA-replication-cycle. However, the relationship between cell-cycle regulators and centrosome dupl
- PMID 27253419
- Effect of MPS1 Inhibition on Genotoxic Stress Responses in Murine Tumour Cells.
- Suzuki M1, Yamamori T2, Yasui H1, Inanami O2.
- Anticancer research.Anticancer Res.2016 Jun;36(6):2783-2792.
- BACKGROUND/AIM: The monopolar spindle 1 (MPS1) is a serine/threonine kinase that plays an important role in spindle assembly checkpoint signaling. To determine the possible relationship between MPS1 inhibition and genotoxic stress responses, herein we examined whether MPS1 inhibition influences cell
- PMID 27272789
Japanese Journal
- Inhibition of the mitochondrial fission protein dynamin-related protein 1 (Drp1) impairs mitochondrial fission and mitotic catastrophe after x-irradiation
- Fanconi貧血における中心体制御の破綻 (特集 細胞内小器官と血液疾患)
Related Links
- The presence of more than two centrosomes (centrosome amplification), severely disturbs mitotic process and cytokinesis via formation of more than two spindle poles, resulting in an increased frequency of chromosome segregation errors ...
- 16 Oct 2011 ... The turn of the 21st century had witnessed a surge of interest in the centrosome and its causal relation to human cancer development - a postulate that has existed for almost a century. Centrosome amplification (CA) is ...
Related Pictures
★リンクテーブル★
[★]
- 英
- centrosome duplication、centrosome amplification
[★]
- 関
- centrosome amplification
[★]
- 関
- amplify