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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/10/15 16:03:59」(JST)

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A cementoblast is a biological cell that forms from the follicular cells around the root of a tooth, and whose biological function is cementogenesis, which is the creation of cementum (the hard tissue that covers the root of the tooth). Cementoblasts lay down the organic matrix of cementum which later gets mineralized by minerals from oral fluids. Thus the cementoblasts lay down collagen and secrete osteocalcin and sialoprotein. They possess all the organelles associated with protein synthesis such as RER and Golgi apparatus.

The mechanism of differentiation of the cementoblasts is controversial but circumstantial evidence suggests that an epithelium or epithelial component may cause dental follicle cells to differentiate into cementoblasts, characterised by an increase in length. The initially formed cementum in coronal two-thirds of the root is acellular, but when the cementoblasts get trapped in lacunae in their own matrix like bone cells, the cementum is called cellular or secondary cementum and is present only in the apical third of the root.

Once in this situation, the cementoblasts lose their secretory activity and become cementocytes.

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1. 歯性感染症の疫学、病因、および臨床症状epidemiology pathogenesis and clinical manifestations of odontogenic infections [show details]
…the root of the tooth from the neck to the apex. Cementum is structurally similar to bone, with cementocytes lying in lacunae and interconnected by canaliculi. Thick collagen bundles, known as Sharpey fibers…
2. 歯の解剖学的構造および発達anatomy and development of the teeth [show details]
…becoming fused to or resorbed by the adjacent alveolar bone. It is structurally similar to bone, with cementocytes lying in lacunae and interconnected by canaliculi. In addition, cementum provides the tissues…

English Journal

Alveolar ridge preservation with autologous particulated dentin-a case series.

Valdec S1, Pasic P2, Soltermann A3, Thoma D4, Stadlinger B2, Rücker M2.
International journal of implant dentistry.Int J Implant Dent.2017 Dec;3(1):12. doi: 10.1186/s40729-017-0071-9. Epub 2017 Mar 30.
PMID 28361377

Effects of the incorporation of ε-aminocaproic acid/chitosan particles to fibrin on cementoblast differentiation and cementum regeneration.

Park CH1, Oh JH1, Jung HM1, Choi Y1, Rahman SU1, Kim S2, Kim TI2, Shin HI3, Lee YS4, Yu FH5, Baek JH4, Ryoo HM4, Woo KM6.
Acta biomaterialia.Acta Biomater.2017 Oct 1;61:134-143. doi: 10.1016/j.actbio.2017.07.039. Epub 2017 Jul 29.
PMID 28764948

Localization of RELM-β/FIZZ2 Is Associated with Cementum Formation.

Hosoya A1, Takahama A1, Nakamura H1.
Anatomical record (Hoboken, N.J. : 2007).Anat Rec (Hoboken).2017 Oct;300(10):1865-1874. doi: 10.1002/ar.23636. Epub 2017 Jul 18.
PMID 28681425

Japanese Journal

Heavily Induced Root Resorption Stimulates Wnt5a Expression in Cementoblasts

Saito-Goto Hitomi,Kikuta Jun,Shimizu Mami,Hikida Takuji,Kasai Kazutaka
International Journal of Oral-Medical Sciences 17(3-4), 69-80, 2019
… Additionally, the effects of different compression forces(CFs)on Wnt5a production were investigated using human periodontal ligament(hPDL) cells and human cementoblast-like cells in vitro. …
NAID 130007629073

Caspase-mediated Apoptosis by Compressive Force Induces RANKL in Cementoblasts

Yamaguchi Masaru,Minato Yukari,Shimizu Mami,Kikuta Jun,Hikida Takuji,Kasai Kazutaka
International Journal of Oral-Medical Sciences 16(2), 31-38, 2018
… In this study, human cementoblast-like cells (HCEMs) were cultured and subjected to pressure conditions assumed during orthodontic tooth movement in vitro. …
NAID 130006320938

Response to light compressive force in human cementoblasts in vitro

MATSUNAGA Kenji,ITO Chika,NAKAKOGAWA Kaichi,SUGIUCHI Akina,SAKO Ryo,FURUSAWA Masahiro,MURAMATSU Takashi
Biomedical Research 37(5), 293-298, 2016
… A human cementoblast cell line (HCEM) was loaded for 12 h by mounting coverslips (0.25 gf/cm2). …
NAID 130005432960