WordNet

being or suggesting a cavern; "vast cavernous chambers hollowed out of limestone"
of or relating to either of the two major arteries supplying blood to the head and neck
an abnormal passage leading from a suppurating cavity to the body surface (同)sinus

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ほら穴の多い / ほら穴のような
頚(けい)動脈 / 頚動脈の
瘻(ろう)菅(長い菅状になった潰瘍)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/16 22:16:19」(JST)

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A carotid-cavernous fistula (CCF) results from an abnormal communication between the arterial and venous systems within the cavernous sinus in the skull. It is a type of arteriovenous fistula. As arterial blood under high pressure enters the cavernous sinus, the normal venous return to the cavernous sinus is impeded and this causes engorgement of the draining veins, manifesting most dramatically as a sudden engorgement and redness of the eye of the same side.

Causes

Carotid cavernous fistulae may form following closed or penetrating head trauma, surgical damage, rupture of an intracavernous aneurysm, or in association with connective tissue disorders, vascular diseases and dural fistulas.

Classification

Various classifications have been proposed for CCF. They may be divided into low-flow or high-flow, traumatic or spontaneous and direct or indirect. The traumatic CCF typically occurs after a basal skull fracture. The spontaneous dural cavernous fistula which is more common usually results from a degenerative process in older patients with systemic hypertension and atherosclerosis. Direct fistulas occur when the Internal Carotid artery (ICA) itself fistulizes into the Cavernous sinus whereas indirect is when a branch of the ICA or External Carotid artery (ECA) communicates with the cavernous sinus.

A popular classification divides CCF into four varieties depending on the type of arterial supply.

Type	Description
A	Fistulous supply from the internal carotid artery
B	Supply from the dural branches of internal carotid artery
C	from meningeal branches of ext carotid artery
D	combined ICA+ECA

Presentation

dilated blood vessels in the eye in CCF ^[1]

CCF symptoms include bruit (a humming sound within the skull due to high blood flow through the arteriovenous fistula), progressive visual loss, and pulsatile proptosis or progressive bulging of the eye due to dilatation of the veins draining the eye. Pain is the symptom that patients often find the most difficult to tolerate.

Patients usually present with sudden or insidious onset of redness in one eye, associated with progressive proptosis or bulging.

They may have a history of similar episodes in the past.

Diagnosis

Selective angiography of the external carotid artery showing an indirect type D right carotid cavernous fistula, filling of the cavernous sinus (arrow) and retrograde drainage into the right superior ophthalmic vein (arrowhead) ^[1]

This is based on MRI scan, magnetic resonance angiography and CT scan. A cerebral digital subtraction angiography (DSA) enhances visualization of the fistula.

CT scans classically show an enlarged superior ophthalmic vein, cavernous sinus enlargement ipsilateral (same side) as the abnormality and possibly diffuse enlargement of all the extraocular muscles resulting from venous engorgement.

Selective arteriography is used to evaluate arteriovenous fistulas.

Treatment

The mainstay of treatment for CCF is endovascular therapy. This may be transarterial (mostly in the case of direct CCF) or transvenous (most commonly in indirect CCF). Occasionally, more direct approaches, such as direct transorbital puncture of the cavernous sinus or cannulation of the draining superior orbital vein are used when conventional approaches are not possible. Spontaneous resolution of indirect fistulae has been reported but is uncommon. Staged manual compression of the ipsilateral carotid has been reported to assist with spontaneous closure in selected cases.

Direct CCF may be treated by occlusion of the affected cavernous sinus (coils, balloon, liquid agents), or by reconstruction of the damaged internal carotid artery (stent, coils or liquid agents).

Indirect CCF may be treated by occlusion of the affected cavernous sinus with coils, liquid agents or a combination of both.^[2]^[3]^[4]

External links

Carotid Cavernous Fistula CT and MRI images

References

^ ^a ^b Thinda, S; Melson, MR; Kuchtey, RW (Jul 28, 2012). "Worsening angle closure glaucoma and choroidal detachments subsequent to closure of a carotid cavernous fistula.". BMC ophthalmology 12: 28. doi:10.1186/1471-2415-12-28. PMC 3412712. PMID 22839357.
^ Ong, CK; Wang, LL; Parkinson, RJ; Wenderoth, JD (2009). "Onyx embolisation of cavernous sinus dural arteriovenous fistula via direct percutaneous transorbital puncture". Journal of Medical Imaging and Radiation Oncology 53 (3): 291–5. doi:10.1111/j.1754-9485.2009.02086.x. PMID 19624295.
^ Bhatia, Kartik D; Wang, Lily; Parkinson, Richard J; Wenderoth, Jason D (2009). "Successful Treatment of Six Cases of Indirect Carotid-Cavernous Fistula with Ethylene Vinyl Alcohol Copolymer (Onyx) Transvenous Embolization". Journal of Neuro-Ophthalmology 29 (1): 3–8. doi:10.1097/WNO.0b013e318199c85c. PMID 19458567.
^ Nadarajah, M.; Power, M.; Barry, B.; Wenderoth, J. (2011). "Treatment of a traumatic carotid-cavernous fistula by the sole use of a flow diverting stent". Journal of NeuroInterventional Surgery 4 (3): e1. doi:10.1136/neurintsurg-2011-010000. PMID 21990483.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 頚動脈海綿静脈洞瘻 carotid cavernous fistulas
2. トロサハント症候群 tolosa hunt syndrome
3. 成人における頭蓋骨骨折 skull fractures in adults
4. 成人における嚥下性肺炎 aspiration pneumonia in adults
5. 成人における便失禁 fecal incontinence in adults

English Journal

Treatment of a carotid cavernous fistula via direct transovale cavernous sinus puncture.

Gil A, López-Ibor L, Lopez-Flores G, Cuellar H, Murias E, Rodríguez-Boto G.SourceInterventional Neuroradiology Unit and.
Journal of neurosurgery.J Neurosurg.2013 May 10. [Epub ahead of print]
Endovascular treatment is the treatment of choice for indirect carotid cavernous fistulas (CCFs). Direct surgical obliteration of CCFs is recommended in highly symptomatic patients or in those with an aggressive pattern of venous drainage. However, this is a technically challenging approach associat
PMID 23662818

Endovascular treatment of carotid cavernous sinus fistula: A systematic review.

Korkmazer B, Kocak B, Tureci E, Islak C, Kocer N, Kizilkilic O.SourceBora Korkmazer, Burak Kocak, Civan Islak, Naci Kocer, Osman Kizilkilic, Division of Neuroradiology, Department of Radiology, Cerrahpasa School of Medicine, Istanbul University, 34098 Istanbul, Turkey.
World journal of radiology.World J Radiol.2013 Apr 28;5(4):143-55. doi: 10.4329/wjr.v5.i4.143.
Carotid cavernous sinus fistulas are abnormal communications between the carotid system and the cavernous sinus. Several classification schemes have described carotid cavernous sinus fistulas according to etiology, hemodynamic features, or the angiographic arterial architecture. Increased pressure w
PMID 23671750

Japanese Journal

両側性特発性頸動脈海綿静脈洞瘻の1例

三宮瞳,小暮朗子,小暮俊介他
眼科 54(13), 1945-1951, 2012-12-00
NAID 40019535231

症例報告橈骨動脈バイパスを経由した塞栓術を行った外傷性内頚動脈海綿静脈洞瘻の1例

清水立矢,上山博康,瀧澤克己他
JNET : journal of neuroendovascular therapy 6(3), 189-195, 2012-10-00
NAID 40019558296

Related Pictures

Carotid cavernous fistula Images of 海綿静脈洞 - JapaneseClass.jp Fistula Treatment in India RiT radiology: Carotid Cavernous Fistula (CCF) Carotid-cavernous sinus fistula; Fistula, Carotid Artery-Cavernous Sinus; Traumatic Exophthalmos secondary to a carotid cavernous fistula

★リンクテーブル★

リンク元	「CCF」
関連記事	「cavernous」「carotid」

「CCF」

Carotid-cavernous fistula
	Oblique section through the cavernous sinus.
Classification and external resources
DiseasesDB	2152
eMedicine	oph/204 radio/134
MeSH	D020216