UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. フェニルケトン尿症の概要 overview of phenylketonuria
2. ALA脱水酵素欠損性ポルフィリン症 ala dehydratase porphyria
3. ポルフィリン症：概要 porphyrias an overview
4. チロシン代謝障害 disorders of tyrosine metabolism
5. 全身疾患と関連した遺伝性ニューロパチー hereditary neuropathies associated with generalized disorders

English Journal

Molecular and enzymatic characterization of two enzymes BmPCD and BmDHPR involving in the regeneration pathway of tetrahydrobiopterin from the silkworm Bombyx mori.

Li W1, Gong M1, Shu R1, Li X1, Gao J1, Meng Y2.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.Comp Biochem Physiol B Biochem Mol Biol.2015 Aug;186:20-7. doi: 10.1016/j.cbpb.2015.04.006. Epub 2015 Apr 18.
Tetrahydrobiopterin (BH4) is an essential cofactor of aromatic amino acid hydroxylases and nitric oxide synthase so that BH4 plays a key role in many biological processes. BH4 deficiency is associated with numerous metabolic syndromes and neuropsychological disorders. BH4 concentration in mammals is
PMID 25899859

Quantitative proteomics analysis by iTRAQ in human nuclear cataracts of different ages and normal lens nuclei.

Zhou HY1,2, Yan H1, Wang LL2, Yan WJ3, Shui YB4, Beebe DC4.
Proteomics. Clinical applications.Proteomics Clin Appl.2015 Aug;9(7-8):776-86. doi: 10.1002/prca.201400061. Epub 2015 Mar 21.
PURPOSE: The goal of this study was to quantitatively identify the differentially expressed proteins in nuclear cataracts of different ages and normal lens nuclei in humans.EXPERIMENTAL DESIGN: Forty-eight human lens nucleus samples with hardness grades III, IV were obtained during cataract surgery
PMID 25418515

[Effect of tianma gouteng decoction on the endothelial function and the renal protein expression in spontaneously hypertensive rats].

Li Y, Ke Y, Jiang JY, Li XJ, Jiang YB.
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban.Zhongguo Zhong Xi Yi Jie He Za Zhi.2015 Apr;35(4):481-7.
OJECTIVE: To observe the effect of tianma gouteng decoction (TGD) on the endothelial function and the renal protein expression of spontaneously hypertensive rats, and to analyze its possible mechanism.METHODS: Totally 18 6-week-old SHR were randomly divided into 3 groups according to randomized bloc
PMID 26043575

Mutations in the BH4-metabolizing genes GTP cyclohydrolase I,6-pyruvoyl-tetrahydropterin synthase, sepiapterin reductase, carbinolamine-4a-dehydratase, and dihydropteridine reductase

Chromosomal location of two human genes encoding tetrahydrobiopterin-metabolizing enzymes : 6-pyruvoyl-tetrahydropterin synthase maps to 11q22.3-q23.3, and pterin-4a-carbinolamine dehydratase maps to 10q22

Identity of 4α-carbinolamine dehydratase, a component of the phenylalanine hydroxylation system, and DCoH, a transregulator of homeodomain proteins

リンク元	「カルビノールアミン脱水酵素」
拡張検索	「carbinolamine dehydratase deficiency」
関連記事	「dehydratase」「carbinolamine」