Particle-induced bone loss by osteoclasts is a common cause of aseptic loosening around implants. This study investigates whether caffeic acid phenethyl ester (CAPE), a potent and specific inhibitor of nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 1 and nuclear factor kappa
CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation.
Kim HY1, Yoon JY1, Yun JH2, Cho KW3, Lee SH1, Rhee YM4, Jung HS3, Lim HJ5, Lee H5, Choi J6, Heo JN5, Lee W2, No KT7, Min D8, Choi KY1.
Cell death and differentiation.Cell Death Differ.2015 Jun;22(6):912-20. doi: 10.1038/cdd.2014.238. Epub 2015 Jan 30.
The positive roles of the Wnt/β-catenin pathway in osteoblast differentiation and bone mineral density (BMD) maintenance have been clearly demonstrated in both animal experiments and clinical investigations. CXXC finger protein 5 (CXXC5), a recently identified negative regulator of the Wnt/β-caten
Bone grafting materials in critical defects in rabbit calvariae. A systematic review and quality evaluation using ARRIVE guidelines.
Delgado-Ruiz RA1, Calvo Guirado JL2, Romanos GE3.
Clinical oral implants research.Clin Oral Implants Res.2015 May 20. doi: 10.1111/clr.12614. [Epub ahead of print]
AIMS: To perform a systematic literature review of the regenerative potential of bone substitutes used to fill critical size defects (CSDs) in rabbit calvariae; to determine the quality of the included studies using ARRIVE guidelines.MATERIAL AND METHODS: An Internet search was performed in duplicat
… The calvariae of 14 rats were exposed, and two plastic caps–one with 0.03% PDGF and a chitosan sponge and one with a chitosan sponge alone–were placed. …
Journal of Biomedicine and Biotechnology 2011, 727063, 2011
Wear debris causes biological response which can result in periprosthetic osteolysis after total joint replacement surgery. Nuclear factor-kappa B (NFκB), a representative transcription factor involve …
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DeviantArt is the world's largest online social community for artists and art enthusiasts, allowing people to connect through the creation and sharing of art. ... CRADLE - Chapter 4 Cradle – Chapter 4 We don't always know when the ...