ブタンジオール発酵
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/01 11:53:59」(JST)
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2,3-Butanediol fermentation is anaerobic fermentation of glucose with 2,3-butanediol as one of the end products. The overall stoichiometry of the reaction is
- 2 pyruvate + NADH --> 2CO2 + 2,3-butanediol.
Butanediol fermentation is typical for Klebsiella and Enterobacter[1] and is tested for using the Voges–Proskauer (VP) test.
The metabolic function of 2,3-butanediol is not known.
Comparison with mixed acid fermentation
2,3-butanediol fermentation produces smaller amounts of acid than mixed acid fermentation, and butanediol, ethanol, CO2 and H2 are the end products. While equal amounts of CO2 and H2 are created during mixed acid fermentation, butanediol fermentation produces more than twice the amount of CO2 because the gases are not produced only by formate hydrogen lyase like they are in the mixed acid fermentation
References
- M.Madigan & J. Martinko, 11th edition, (2006) Brock's Biology of Microorganisms, NJ, Pearson Prentice Hall, (p. 351-355)
- ^ H. Geckil, Z. Barak, D. M. Chipman, S. O. Erenler, D. A. Webster and B. C. Stark. (2004). "Enhanced production of acetoin and butanediol in recombinant Enterobacter aerogenes carrying Vitreoscilla hemoglobin gene.". Bioprocess. Biosyst. Eng. 26 (5): 325–30. doi:10.1007/s00449-004-0373-1. PMID 15309606.
External links
- http://biocyc.org/META/new-image?type=PATHWAY&object=P125-PWY
UpToDate Contents
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English Journal
- Metabolic engineering of Klebsiella pneumoniae and in silico investigation for enhanced 2,3-butanediol production.
- Rathnasingh C1, Park JM1, Kim DK1,2, Song H3, Chang YK2.
- Biotechnology letters.Biotechnol Lett.2016 Jun;38(6):975-82. doi: 10.1007/s10529-016-2062-y. Epub 2016 Feb 17.
- OBJECTIVES: To improve the production of 2,3-butanediol (2,3-BD) in Klebsiella pneumoniae, the genes related to the formation of lactic acid, ethanol, and acetic acid were eliminated.RESULTS: Although the cell growth and 2,3-BD production rates of the K. pneumoniae ΔldhA ΔadhE Δpta-ackA strain we
- PMID 26886192
- Insights into CO2 Fixation Pathway of Clostridium autoethanogenum by Targeted Mutagenesis.
- Liew F1, Henstra AM2, Winzer K2, Köpke M3, Simpson SD3, Minton NP4.
- mBio.MBio.2016 May 24;7(3). pii: e00427-16. doi: 10.1128/mBio.00427-16.
- The future sustainable production of chemicals and fuels from nonpetrochemical resources and reduction of greenhouse gas emissions are two of the greatest societal challenges. Gas fermentation, which utilizes the ability of acetogenic bacteria such as Clostridium autoethanogenum to grow and convert
- PMID 27222467
- The fermentation product 2,3-butanediol alters P. aeruginosa clearance, cytokine response and the lung microbiome.
- Nguyen M1, Sharma A2, Wu W3, Gomi R2, Sung B3, Hospodsky D1, Angenent LT1, Worgall S2,3.
- The ISME journal.ISME J.2016 May 13. doi: 10.1038/ismej.2016.76. [Epub ahead of print]
- Diseases that favor colonization of the respiratory tract with Pseudomonas aeruginosa are characterized by an altered airway microbiome. Virulence of P. aeruginosa respiratory tract infection is likely influenced by interactions with other lung microbiota or their products. The bacterial fermentatio
- PMID 27177192
Japanese Journal
- 2,3-Butanediol recovery from fermentation broth by alcohol precipitation and vacuum distillation(BIOCHEMICAL ENGINEERING)
- Extraction of 2,3-Butanediol with Aqueous Two-Phase Systems Formed by Water-Miscible Organic Solvents and Inorganic Salts
- Solvent Extraction Research and Development, Japan 21(2), 181-190, 2014
- NAID 130004669676
- Metabolic engineering of a novel Klebsiella oxytoca strain for enhanced 2,3-butanediol production(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
Related Links
- Butanediol fermentation (Q209161) From Wikidata Jump to: navigation, search No description defined No aliases defined edit Language Label Description Also known as English Butanediol fermentation No description defined edit ...
- K. B. McCALLANDC. E. GEORGI TABLE 1. 2,3-Butanediol production by Aerobacter aerogenes (A-5) 2,3-Butanediol Yield SucroseInitialCon-SucroseUtilized Fermentation Percent of theory Time _____ centration Sugar Sugar ...
★リンクテーブル★
[★]
- 英
- butylene glycol fermentation
- 同
- ブタンジオール発酵 butanediol fermentation、アセトイン発酵 acetoin fermentation
[★]
ブタンジオール
- 関
- butylene glycol