関: mediterranean spotted fever

WordNet

a rise in the temperature of the body; frequently a symptom of infection (同)febrility, febricity, pyrexia, feverishness
intense nervous anticipation; "in a fever of resentment"
highly excited; "a fevered imagination"

PrepTutorEJDIC

〈U〉《しばしばa fever》(身体の異常な)『熱』,発熱 / 〈U〉『熱病』 / 〈U〉〈C〉(…に対する)『興奮』,熱狂《+『for』+『名』》
(比較変化なし)《名詞の前にのみ用いて》熱のある,熱病にかかった / 熱にうかされたような,興奮した / (憎しみなどが)異常に強い

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/07/09 04:32:04」(JST)

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Boutonneuse fever (also called Mediterranean spotted fever, fièvre boutonneuse, Kenya tick typhus, Indian tick typhus, Marseilles fever, or African tick-bite fever) is a fever as a result of a rickettsial infection caused by the bacterium Rickettsia conorii and transmitted by the dog tick Rhipicephalus sanguineus. Boutonneuse fever can be seen in many places around the world, although it is endemic in countries surrounding the Mediterranean Sea. This disease was first described in Tunisia in 1910 by Conor and Bruch and was named boutonneuse (French for "spotty") due to its papular skin rash characteristics.^[1]^[2]

Presentation

After an incubation period around seven days, the disease manifests abruptly with chills, high fevers, muscular and articular pains, severe headache, and photophobia. The location of the bite forms a black ulcerous crust (tache noire). Around the fourth day of the illness, a widespread rash appears, first macular and then maculopapular and sometimes petechial.

Diagnosis

The diagnosis is made with serologic methods, either the classic Weil-Felix test (agglutination of Proteus OX strains ), ELISA, or immunofluorescence assays in the bioptic material of the primary lesion.

Treatment

The illness can be treated with tetracyclines (doxycycline is the preferred treatment), chloramphenicol, macrolides or fluoroquinolones.

References

^ ^a ^b Rovery C, Brouqui P, Raoult D (2008). "Questions on Mediterranean Spotted Fever a Century after Its Discovery". Emerg Infect Dis 14 (9): 1360–1367. doi:10.3201/eid1409.071133. PMC 2603122. PMID 18760001.
^ Conor, A; A Bruch (1910). "Une fièvre éruptive observée en Tunisie". Bull Soc Pathol Exot Filial 8: 492–496.

External links

Mediterranean Spotted Fever Clinical Resources

UpToDate Contents

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1. その他の紅斑熱群リケッチア感染 other spotted fever group rickettsial infections
2. リケッチア痘瘡 rickettsialpox
3. 免疫能の正常な患者における発熱および発疹 fever and rash in the immunocompetent patient
4. ロッキー山紅斑熱の臨床症状および診断 clinical manifestations and diagnosis of rocky mountain spotted fever
5. 発疹熱の疫学および臨床症状 the epidemiology and clinical manifestations of murine typhus

English Journal

[Acute myocarditis complicating Mediterranean spotted fever. A case report].

Ben Mansour N1, Barakett N2, Hajlaoui N2, Haggui A2, Filali T2, Dahmen R2, Fehri W2, Haouala H2.Author information 1Service de cardiologie du Professeur Haouala, hôpital militaire d'instruction, Tunis, Tunisie. Electronic address: benmansournizar@voila.fr.2Service de cardiologie du Professeur Haouala, hôpital militaire d'instruction, Tunis, Tunisie.AbstractMediterranean spotted fever (MSF) due to Rickettsia conorii is the most important tick-borne disease occurring in North Africa. The first description of MSF was made by Conor and Brush in 1910 in Tunisia. Clinical diagnosis relies on the association of fever, rash and inoculation's scar during summertime. Prognosis in MSF is usually good, however malignant forms were described. These forms occur in patients with comorbidities. G6PD deficiency is a classic ground for severe forms of MSF. Myocarditis is an uncommon complication in MSF; only few cases were reported in the literature. We report a new case of myocarditis complicating MSF in a 15-year-old patient with G6PD deficiency. The patient presented with fever and rash, evocative of MSF; he reported chest pain and the electrocardiogram showed ST segment elevation in anterior leads. Troponin level was elevated. Echocardiogram showed left ventricular dysfunction with 40% ejection fraction. Serologic tests confirmed R. conorii recent infection. Antibiotic treatment with vibramycine and rifadine was started. Patient also received classic treatment of myocarditis with left ventricular dysfunction associating CEI, ß-bloquers and diuretics. Evolution was favourable with complete recovery of left ventricular function. Myocarditis is an uncommon but severe complication of MSF. Early diagnosis and treatment allow favorable evolution.
Annales de cardiologie et d'angéiologie.Ann Cardiol Angeiol (Paris).2014 Feb;63(1):55-7. doi: 10.1016/j.ancard.2011.05.003. Epub 2011 May 25.
Mediterranean spotted fever (MSF) due to Rickettsia conorii is the most important tick-borne disease occurring in North Africa. The first description of MSF was made by Conor and Brush in 1910 in Tunisia. Clinical diagnosis relies on the association of fever, rash and inoculation's scar during summe
PMID 21664598

A case of spotted fever rickettsiosis in a human immunodeficiency virus-positive patient.

Colomba C, Siracusa L, Madonia S, Saporito L, Bonura C, De Grazia S, Giammanco GM.
Journal of medical microbiology.J Med Microbiol.2013 Sep;62(Pt 9):1363-4. doi: 10.1099/jmm.0.053546-0. Epub 2013 Jun 20.
PMID 23788593

Q fever and Mediterranean spotted fever associated with hemophagocytic syndrome: case study and literature review.

Lecronier M, Prendki V, Gerin M, Schneerson M, Renvoisé A, Larroche C, Ziol M, Fain O, Mekinian A.Author information Service de Médecine Interne, Université Paris 13, AP-HP, Hôpital Jean Verdier, Bondy, France.AbstractBACKGROUND: Hemophagocytosis during Q fever (QF) and Mediterranean spotted fever (MSF) is rare and only a few cases have been reported. We aimed to investigate the characteristics, outcome, and treatment of QF/MSF-associated hemophagocytosis.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.Int J Infect Dis.2013 Aug;17(8):e629-33. doi: 10.1016/j.ijid.2012.12.026. Epub 2013 Feb 9.
BACKGROUND: Hemophagocytosis during Q fever (QF) and Mediterranean spotted fever (MSF) is rare and only a few cases have been reported. We aimed to investigate the characteristics, outcome, and treatment of QF/MSF-associated hemophagocytosis.METHODS: We retrospectively reviewed all patients with a d
PMID 23402798

Japanese Journal

A recombinant Rickettsia conorii vaccine protects guinea pigs from experimental boutonneuse fever and Rocky Mountain spotted fever

Infect.Immun. 58, 646-653, 1990
NAID 10004787223

The histology of "taches noires" of boutonneuse fever and demonstration of Rickettsia conorii in them by immunofluorescense.

Virchows Arch 400, 309-317, 1983
NAID 30014137019

Spotted fever II An experimental study of fievre boutonneuse

J Exp Med 64, 601-623, 1936
NAID 30017421814

Related Pictures

★リンクテーブル★

リンク元	「Mediterranean spotted fever」

「Mediterranean spotted fever」

Boutonneuse fever
	Typical eschar and spots on the leg of a patient with Boutonneuse fever
Classification and external resources
Specialty	Infectious disease
ICD-10	A77.1
ICD-9-CM	082.1
DiseasesDB	31780
MeSH	D001907
	[edit on Wikidata]

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地中海紅斑熱、地中海斑点熱、Mediterranean紅斑熱

関: boutonneuse fever

[rovery-1] Rovery C, Brouqui P, Raoult D (2008). "Questions on Mediterranean Spotted Fever a Century after Its Discovery". Emerg Infect Dis 14 (9): 1360–1367. doi:10.3201/eid1409.071133. PMC 2603122. PMID 18760001.

[2] Conor, A; A Bruch (1910). "Une fièvre éruptive observée en Tunisie". Bull Soc Pathol Exot Filial 8: 492–496.

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案内

案内

boutonneuse fever