- 関
- enhancing antibody
WordNet
- any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
- the act of obstructing or deflecting someones movements (同)block
PrepTutorEJDIC
- 抗体,免疫体,抗毒素
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/13 11:27:28」(JST)
[Wiki en表示]
A blocking antibody is an antibody that does not have a reaction when combined with an antigen, but prevents other antibodies from combining with that antigen.[1]
The term can also be used for inhibiting antibody, prozone phenomenon and, agglutination reaction.
Blocking antibodies have been described as a mechanism for HSV-1 to evade the immune system.[2]
See also
- Neutralizing antibody
- Binding antibody
References
- ^ Blocking Antibodies at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Hook LM, Huang J, Jiang M, Hodinka R, Friedman HM (July 2008). "Blocking antibody access to neutralizing domains on glycoproteins involved in entry as a novel mechanism of immune evasion by herpes simplex virus type 1 glycoproteins C and E". J. Virol. 82 (14): 6935–41. doi:10.1128/JVI.02599-07. PMC 2446985. PMID 18480440.
UpToDate Contents
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English Journal
- Insights into the interaction of CD4 with anti-CD4 antibodies.
- Bui VC1, Nguyen TH2.
- Immunobiology.Immunobiology.2017 Feb;222(2):148-154. doi: 10.1016/j.imbio.2016.10.010. Epub 2016 Oct 17.
- Knowledge about the mechanism by which some antibodies can block HIV-1 entry is critical to our understanding of their function and may offer new avenues for controlling the adhesion of HIV-1 to the host cells. While much progress has been made, this mechanism remains unclear. Here, atomic force mic
- PMID 27773661
- A novel label-free cell-based assay technology using biolayer interferometry.
- Verzijl D1, Riedl T1, Parren PW2, Gerritsen AF3.
- Biosensors & bioelectronics.Biosens Bioelectron.2017 Jan 15;87:388-395. doi: 10.1016/j.bios.2016.08.095. Epub 2016 Aug 28.
- Biolayer interferometry (BLI) is a well-established optical label-free technique to study biomolecular interactions. Here we describe for the first time a cell-based BLI (cBLI) application that allows label-free real-time monitoring of signal transduction in living cells. Human A431 epidermoid carci
- PMID 27589401
- The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor.
- Khodorova A1, Nicol GD2, Strichartz G3.
- Neuroscience.Neuroscience.2017 Jan 6;340:384-397. doi: 10.1016/j.neuroscience.2016.10.064. Epub 2016 Nov 5.
- The p75 neurotrophin receptor (p75NTR) and its activation of the sphingomyelin signaling cascade are essential for mechanical hypersensitivity resulting from locally injected nerve growth factor (NGF). Here the roles of the same effectors, and of the tropomyosin receptor kinase A (TrkA) receptor, ar
- PMID 27826102
Japanese Journal
- Enhanced antibody-dependent cellular phagocytosis by chimeric monoclonal antibodies with tandemly repeated Fc domains(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Nagashima Hiroaki,Ootsubo Michiko,Fukazawa Mizuki,Motoi Sotaro,Konakahara Shu,Masuho Yasuhiko
- Journal of bioscience and bioengineering 111(4), 391-396, 2011-04
- … We previously reported that chimeric monoclonal antibodies (mAbs) with tandemly repeated Fc domains, which were developed by introducing tandem repeats of Fc domains downstream of 2 Fab domains, augmented binding avidities for all Fcγ receptors, resulting in enhanced antibody (Ab)-dependent cellular cytotoxicity. … An Fcγ receptor-blocking study demonstrated that T3-Ab mediated ADCP via both FcγRIA and FcγRIIA, whereas M-Ab mediated ADCP exclusively via FcγRIA. …
- NAID 110008607490
- Ablation of the Ccr2 gene exacerbates polyarthritis in interleukin-1 receptor antagonist-deficient mice
- Fujii Hiroshi,Baba Tomohisa,Ishida Yuko,Kondo Toshikazu ,Yamagishi Masakazu ,Kawano Mitsuhiro ,Mukaida Naofumi
- Arthritis and Rheumatism 63(1), 96-106, 2011-01
- … Anti-mouse CXCR2 antibody was injected into Il1rn and Ccr2-double-deficient mice for blocking experiments. …
- NAID 120002754103
Related Links
- Antibodies – Blocking/Neutralization Methods, Techniques, Protocols-Antibodies – Blocking/Neutralization Methods, Techniques, Protocols by Gentaur • Definition: A method to test the specificity of antibodies or to reduce ...
- antibody [an´tĭ-bod″e] an immunoglobulin molecule having a specific amino acid sequence that gives each antibody the ability to adhere to and interact only with the antigen that induced its synthesis. This antigen-specific property of ...
Related Pictures
★リンクテーブル★
[★]
- 英
- incomplete antibody
- 同
- 阻止抗体 遮断抗体 blocking antibody、非定型抗体 atypical antibody、一価抗体 univalent antibody
- 例)抗A、抗B凝集抗体(抗A,抗B抗体、冷式自己抗体)
- 例)温式自己抗体、抗RhD抗体
[★]
- 英
- blocking antibody
- 同
- 遮断抗体
- 関
- 不完全抗体
[★]
- 関
- blocking antibody
[★]
甲状腺刺激阻害抗体