bioactive

• 生理活性の

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bioactivity

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/22 23:12:03」(JST)

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In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter. When a drug is a complex chemical mixture, this activity is exerted by the substance's active ingredient or pharmacophore but can be modified by the other constituents. Activity is generally dosage-dependent. Further, it is common to have effects ranging from beneficial to adverse for one substance when going from low to high doses. Activity depends critically on fulfillment of the ADME criteria.

Whereas a material is considered bioactive if it has interaction with or effect on any cell tissue in the human body, pharmacological activity is usually taken to describe beneficial effects, i.e. the effects of drug candidates as well as a substance's toxicity.

In the study of biomineralisation, bioactivity is often meant as the formation of calcium phosphate deposits on the surface of objects placed in simulated body fluid, a buffer solution with ion content similar to blood.

See also

• Lipinski's Rule of Five, describing molecular properties of drugs
• QSAR, quantitative structure-activity relationship
• Chemical property
• Molecular property
• Physical property
• Chemical structure

References

UpToDate Contents

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• 1. 副甲状腺ホルモン測定およびその臨床応用 parathyroid hormone assays and their clinical use
• 2. カルチノイド症候群の臨床的特徴 clinical features of the carcinoid syndrome
• 3. 急性非代償性心不全の治療におけるネシリチド nesiritide in the treatment of acute decompensated heart failure
• 4. 気管支神経内分泌（カルチノイド）腫瘍：疫学、危険因子、分類、組織学的検査、診断、および病期分類 bronchial neuroendocrine carcinoid tumors epidemiology risk factors classification histology diagnosis and staging
• 5. Neuroendocrine neoplasms of unknown primary site

English Journal

• Ursolic acid from apple pomace and traditional plants: A valuable triterpenoid with functional properties.

• Cargnin ST1, Gnoatto SB2.
• Food chemistry.Food Chem.2017 Apr 1;220:477-489. doi: 10.1016/j.foodchem.2016.10.029. Epub 2016 Oct 8.
• Apple juice production generates a large amount of residue comprising mainly peels, seeds, and pulp, known as apple pomace. In the global context, Brazil ranks 11th in apple production and thousands of tons of apple pomace are produced every year. This by-product is little explored, since it is a ri
• PMID 27855928

• Chemical characterization and protective effect of the Bactris setosa Mart. fruit against oxidative/nitrosative stress.

• Boeing JS1, Ribeiro D2, Chisté RC2, Visentainer JV3, Costa VM4, Freitas M5, Fernandes E6.
• Food chemistry.Food Chem.2017 Apr 1;220:427-437. doi: 10.1016/j.foodchem.2016.09.188. Epub 2016 Sep 30.
• Bactris setosa Mart. is a Brazilian tree from the palm family (Arecaceae), whose fruits are scientifically underexploited. Here, we report, for the first time, the identification and quantification of phenolic compounds and carotenoids in the pulp, seed, and peel extracts of B. setosa fruits and the
• PMID 27855922

• Effects of different extraction temperatures on the physicochemical properties of bioactive polysaccharides from Grifola frondosa.

• Su CH1, Lai MN2, Ng LT3.
• Food chemistry.Food Chem.2017 Apr 1;220:400-405. doi: 10.1016/j.foodchem.2016.09.181. Epub 2016 Sep 29.
• This study examined the effects of different extraction temperatures (70°C, 100°C and 121°C) on the physicochemical properties of water soluble polysaccharides (WSP; GF70, GF100 and GF121, respectively) from Grifola frondosa (GF) fruiting bodies, and evaluating their effects on nitric oxide (NO)
• PMID 27855917

Japanese Journal

• 漢方生薬「川〓(Cnidii Rhizoma)」の抗アレルギー作用とその活性成分について

• 渥美 聡孝,福村 基徳,河崎 亮一,平井 康昭,鳥居塚 和生
• 生薬學雜誌 67(1), 7-12, 2013-02-20
• Background: Preparations containing the aromatic herb Cnidium officinale Makino (Cnidii Rhizoma), known as Senkyu in Japan, are widely used for gynecopathy and allergic skin diseases. However, the the …
• NAID 110009577731

• The 66th CerSJ Awards for Academic Achievements in Ceramic Science and Technology : Development of highly functionalized ceramic biomaterials

• OHTSUKI Chikara
• Journal of the Ceramic Society of Japan = 日本セラミックス協会学術論文誌 121(1410), 129-134, 2013-02-00
• NAID 40019559900

• Potential Antiarrhythmic Effect of Methyl 3,4,5-Trimethoxycinnamate, a Bioactive Substance from Roots of Polygalae Radix : Suppression of Triggered Activities in Rabbit Myocytes

• Zhao Zhenghang,Fang Minfeng,Xiao Dandan [他]
• Biological & pharmaceutical bulletin 36(2), 238-244, 2013-02-00
• NAID 40019558475

Related Links

• Bioactive | Define Bioactive at Dictionary.com

Bioactive definition, any effect on, interaction with, or response from living tissue. See more. Thesaurus Translator Reference Word of the Day Blog Slideshows Apps by Dictionary My Account Log Out Log In follow Dictionary.com ...

• bioactive - definition of bioactive by The Free Dictionary

bi·o·ac·tive (bī′ō-ăk′tĭv) adj. Of or relating to a substance that has an effect on living tissue. bioactive (ˌbaɪəʊˈæktɪv) adj 1. (Biology) (of a substance) having or producing an effect on living tissue ˌbioacˈtivity n Translations bioactive ...

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★リンクテーブル★

リンク元	「bioactivity」「生理活性」
拡張検索	「bioactive substance」

「bioactivity」

　　[★]

• 生理活性、生物活性

関

bioactive、biological activity

「生理活性」

　　[★]

英

bioactivity、bioactive

関

生物活性

「bioactive substance」

　　[★]

• 生理活性物質、生物活性物質

関

biologically active substance