biliary dyskinesia

胆道ジスキネジア、胆嚢ジスキネジア、胆のうジスキネジア、胆道ジスキネジー、胆嚢ジスキネジー

WordNet

1. relating to the bile ducts or the gallbladder
2. abnormality in performing voluntary muscle movements

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/06/27 12:43:14」(JST)

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Biliary dyskinesia
Classification and external resources
Specialty	gastroenterology
ICD-10	K82.8
ICD-9-CM	575.8
DiseasesDB	12297
eMedicine	med/347
MeSH	D001657

Biliary dyskinesia is a disorder of some component of biliary part of the digestive system in which bile physically can not move normally in the proper direction through the tubular biliary tract. It most commonly involves abnormal biliary tract peristalsis muscular coordination within the gallbladder in response to dietary stimulation of that organ to squirt the liquid bile through the common bile duct into the duodenum. Ineffective peristaltic contraction of that structure produces postprandial (after meals) right upper abdominal pain (cholecystodynia) and almost no other problem. When the dyskinesia is localized at the biliary outlet into the duodenum just as increased tonus of that outlet sphincter of Oddi, the backed-up bile can cause pancreatic injury with abdominal pain more toward the upper left side. In general, biliary dyskinesia is the disturbance in the coordination of peristaltic contraction of the biliary ducts, and/or reduction in the speed of emptying of the biliary tree into the duodenum.

Normally, the downstream gallbladder stores and concentrates the bile which originates in liver hepatocyte cells and is released into the microscopic component of the biliary system by the liver. Through aggregating tubules of increasing diameter, the bile leaves the liver and reaches the upstream (proximal) component of the common bile duct. Apparently, the common bile duct beyond (distal to) the gallbladder tends to normally have a greater tone so that the bile backs up into the gallbladder. When bile enters the duodenum (the first part of the small intestine), it aids in digesting the fat within food leaving the stomach. When the bile can not be properly propelled from the not-mechanically-obstructed gallbladder or can not flow out of the end of the common bile duct properly, there is a state of biliary dyskinesia.

So, biliary dyskinesia is a dynamically (functional...not fixed mechanical) obstructive, pain-producing disorder. Obstruction by a stone or tumor is a static, mechanical obstruction and tends to produce a more intense pain known as biliary colic.

Failure of the biliary sphincter of Oddi can be distinguished from failure of the pancreatic sphincter.

Treatment

Laparoscopic cholecystectomy has been used to treat the condition when due to dyskinesia of the gallbladder.

Symptoms may persist after cholecystectomy, and have been linked to the use of proton pump inhibitors.

See also

• Sphincter of Oddi dysfunction
• Dyskinesia

References

UpToDate Contents

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• 1. 成人における胆嚢機能障害 functional gallbladder disorder in adults
• 2. オッディ括約筋機能不全の臨床症状よび診断 clinical manifestations and diagnosis of sphincter of oddi dysfunction
• 3. オッディ括約筋機能不全の治療 treatment of sphincter of oddi dysfunction
• 4. 腹腔鏡下胆嚢摘出術 laparoscopic cholecystectomy
• 5. 急性胆嚢炎：病因、臨床的特徴、および診断 acute cholecystitis pathogenesis clinical features and diagnosis

English Journal

• Poor Reproducibility of Gallbladder Ejection Fraction by Biliary Scintigraphy for Diagnosis of Biliary Dyskinesia.

• Rose JB1, Fields RC1, Strasberg SM2.
• Journal of the American College of Surgeons.J Am Coll Surg.2018 Feb;226(2):155-159. doi: 10.1016/j.jamcollsurg.2017.10.025. Epub 2017 Nov 17.
• PMID 29157795

• Effects of laparoscopic cholecystectomy in normokinetic biliary dyskinesia.

• Pihl KD1, Jones MW2, Deppen JG3, Ferguson TM4, Hanses SM5.
• American journal of surgery.Am J Surg.2018 Jan;215(1):116-119. doi: 10.1016/j.amjsurg.2017.04.012. Epub 2017 Jun 19.
• PMID 28669533

• Sphincter of Oddi dysfunction: the never-ending story has come to a conclusion.

• Costamagna G1.
• Gastrointestinal endoscopy.Gastrointest Endosc.2018 Jan;87(1):211-212. doi: 10.1016/j.gie.2017.07.004.
• PMID 29241851

Japanese Journal

• 慢性膵炎疑診例・胆道ジスキネジー(<特集>消化器心身医療のクリニカルパール)

• 阿部 哲也,福永 幹彦
• 心身医学 50(11), 1033-1037, 2010-11-01
• 慢性膵炎疑診例と胆道ジスキネジーは,ともに器質的異常を認めずに上腹部痛を主訴とする疾患であり,乳頭括約筋機能異常という疾患概念に包括する考えが広まっている.また,心身症の病態を呈する例や,他の機能性消化管障害との並存を示す例が多いことより,これらを障害部位で分類するのではなく,機能性身体症候群として考えることもできる.その際,病状評価には心電図R-R間隔変動係数が有用となる.計測条件の工夫で,多様 …
• NAID 110007811949

• 原因不明の腹部症状(<特集>消化器心身医療のクリニカルパール)

• 福永 幹彦
• 心身医学 50(11), 1011-1014, 2010-11-01
• 近年,原因不明の腹部症状は機能性疾患の枠組みの中で,病態の解明が進んだ.しかしいまなお,経験的理解と対処にとどまっている病態が数多くある.それらは,身体的に器質疾患とも機能疾患ともいえないもの,より深い精神病理を伴っていることが推測されるもの,他科疾患とのはざまにあるものなどである.これらの臨床的な経験を,改めて見直し,光を当てることで,さらなる病態解明が期待できる.このことを目的に,消化管ガス症 …
• NAID 110007811873

Related Pictures

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★リンクテーブル★

リンク元	「胆嚢ジスキネジア」「胆嚢ジスキネジー」「胆道ジスキネジア」「胆のうジスキネジア」「胆道ジスキネジー」
関連記事	「biliary」

「胆嚢ジスキネジア」

　　[★]

英

biliary dyskinesia

関

胆道ジスキネジー、胆道ジスキネジア、胆嚢ジスキネジー、胆のうジスキネジア

「胆嚢ジスキネジー」

　　[★]

英

biliary dyskinesia

関

胆道ジスキネジー、胆道ジスキネジア、胆嚢ジスキネジア、胆のうジスキネジア

「胆道ジスキネジア」

　　[★]

英

biliary dyskinesia

関

胆道ジスキネジー、胆嚢ジスキネジア、胆嚢ジスキネジー、胆のうジスキネジア

「胆のうジスキネジア」

　　[★]

英

biliary dyskinesia

関

胆道ジスキネジー、胆道ジスキネジア、胆嚢ジスキネジア、胆嚢ジスキネジー

「胆道ジスキネジー」

　　[★]

英

biliary dyskinesia

同

胆道ジスキネジア

「biliary」

　　[★]

• adj.

• 胆汁の

関

bile、cholic、gall