βトロンボグロブリン
WordNet
- to remain unmolested, undisturbed, or uninterrupted -- used only in infinitive form; "let her be"
- work in a specific place, with a specific subject, or in a specific function; "He is a herpetologist"; "She is our resident philosopher" (同)follow
- have life, be alive; "Our great leader is no more"; "My grandfather lived until the end of war" (同)live
- be identical to; be someone or something; "The president of the company is John Smith"; "This is my house"
- happen, occur, take place; "I lost my wallet; this was during the visit to my parents house"; "There were two hundred people at his funeral"; "There was a lot of noise in the kitchen"
- have the quality of being; (copula, used with an adjective or a predicate noun); "John is rich"; "This is not a good answer"
- occupy a certain position or area; be somewhere; "Where is my umbrella?" "The toolshed is in the back"; "What is behind this behavior?"
- spend or use time; "I may be an hour"
- stake on the outcome of an issue; "I bet $100 on that new horse"; "She played all her money on the dark horse" (同)wager, play
- the act of gambling; "he did it on a bet" (同)wager
- maintain with or as if with a bet; "I bet she will be there!" (同)wager
- second in order of importance; "the candidate, considered a beta male, was perceived to be unable to lead his party to victory"
- the 2nd letter of the Greek alphabet
- preliminary or testing stage of a software or hardware product; "a beta version"; "beta software"
- beets (同)genus Beta
PrepTutorEJDIC
- 《連結語として補語を伴なって…『である』,…だ,…です / 《位置・場所を表す語句を伴って》(…に)『ある』,いる(occupy a place or situation) / 〈物事が〉『存在する』,ある(exist);〈生物が〉生存する,生きている(live) / 行われる,起こる,発生する(take place, occur) / 存続する,そのままでいる(remain as before) / 《『be to』 do》 / …する予定である,…することになっている / …すべきだ / 《受動態の不定詞を伴って》…できる / 《命令》…するのだ / 《条件節に》…する意図がある / 《『if…were to』 do》…するとしたなら / 《『be』 do『ing』》《進行形》 / 《進行中の動作》…している,しつつある / 《近い未来》…しようとしている,するつもり / 《動作の反復》(いつも)…している / 《『be』+『他動詞の過去分詞』》《受動態》…される,されている / 《『be』+『自動詞の過去分詞』》《完了形》…した[状態にある]
- 『かけ』・(…との)かけ《+『with』+『名』》 / かけた物(金) / かけの対象 / 〈金・物〉'を'『かける』 / (かけ事・ゲームなどで)〈人〉‘と'『かけをする』《+『名』〈人〉+『on』+『名』》 / (…に)『かける』《+『on』(『against』)+『名』(one's do『ing』)》
- ベータ(ギリシア語アルファベットの第2文字;B,β;英語のB,b に遭当)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/17 22:13:08」(JST)
[Wiki en表示]
Beta-thromboglobulin (β-thromboglobulin, also called Pro-Platelet basic protein) is a protein that is stored in alpha-granules of platelets and released in large amounts after platelet activation.[1]
It is a type of Chemokine (C-X-C motif) ligand 7.[2]
Actions
It is a chemoattractant, strongly for fibroblasts and weakly for neutrophils. It is a stimulator of mitogenesis, extracellular matrix synthesis, glucose metabolism, and plasminogen activator synthesis in human fibroblasts.[1]
Beta-Thromboglobulin also affects megakaryocyte maturation, and thus helps in regulating platelet production.[1]
Clinical use
Levels of Beta-Thromboglobulin is used to index platelet activation. It is measured by ELISA in blood plasma or urine, and often in conjunction with Platelet factor 4)[1]
It is elevated in diabetes mellitus.[3]
References
- ^ a b c d Cytokines & Cells Online Pathfinder Encyclopaedia --> Beta-Thromboglobulin Retrieved on August 17, 2009
- ^ Pillai MM, Iwata M, Awaya N, Graf L, Torok-Storb B (May 2006). "Monocyte-derived CXCL7 peptides in the marrow microenvironment". Blood 107 (9): 3520–6. doi:10.1182/blood-2005-10-4285. PMC 1895768. PMID 16391012.
- ^ Page 121 in: Sterne, Jonathan; Kirkwood, Betty R. (2003). Essential medical statistics. Oxford: Blackwell Science. ISBN 0-86542-871-9.
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Measurement of soluble C-type lectin-like receptor 2 in human plasma.
- Kazama F1, Nakamura J2, Osada M1, Inoue O3, Oosawa M2, Tamura S1,4, Tsukiji N1, Aida K5, Kawaguchi A5, Takizawa S5, Kaneshige M5, Tanaka S5, Suzuki-Inoue K1, Ozaki Y1.
- Platelets.Platelets.2015 Dec;26(8):711-9. doi: 10.3109/09537104.2015.1021319. Epub 2015 Apr 9.
- Detection of platelet activation in vivo is useful to identify patients at risk of thrombotic diseases. Platelet factor 4 (PF4) and β-thromboglobulin (β-TG) are used for this purpose; however, they are easily released upon the minimal platelet activation that occurs during sampling. Soluble forms
- PMID 25856065
- Elevated Release of Beta-thromboglobulin and Platelet Factor 4 in Cerebral Infarction Patients with Branch Atheromatous Disease: A Preliminary Report.
- Yokote A1, Hashimoto K, Bikei R, Nakamoto H.
- Neurologia medico-chirurgica.Neurol Med Chir (Tokyo).2015 Oct 15;55(10):809-12. doi: 10.2176/nmc.rc.2015-0042. Epub 2015 Sep 15.
- This study evaluated the levels of the platelet activation markers beta-thromboglobulin (beta-TG) and platelet factor 4 (PF4) in patients with branch atheromatous disease (BAD). Patients with newly diagnosed cerebral infarctions were recruited into the study; those with cardiogenic cerebral infarcti
- PMID 26369876
- Platelet granule secretion mechanisms: Are they modified in sepsis?
- Xu X1, Sun B2.
- Thrombosis research.Thromb Res.2015 Sep 9. pii: S0049-3848(15)30119-5. doi: 10.1016/j.thromres.2015.09.008. [Epub ahead of print]
- Sepsis is a progressive systemic inflammatory response syndrome associated with multi-organ dysfunction caused by overwhelming infection. In sepsis, platelet factor 4, β-thromboglobulin, and other inflammatory mediators are secreted from platelet granules to participate in the inflammatory response
- PMID 26403438
Japanese Journal
- リウマチ膠原病アレルギー患者に対するサフランの効果
- 有光 潤介,萩原 圭祐,大塚 静英,中西 美保,岸田 友紀,井上 隆弥,加藤 由紀子,大谷 安司,尾崎 和成,清水 健太郎,蔭山 充,西田 愼二
- 日本東洋醫學雜誌 = Japanese journal of oriental medicine 62(4), 548-555, 2011-07-20
- … 今回我々は,サフランの臨床的な駆瘀血効果を観察し,血小板活性化の指標である,platelet factor4(PF-4)とbeta-thromboglobulin(β-TG)を瘀血のマーカーとして検討した。 …
- NAID 10029341430
- Platelet release of beta-thromboglobulin and platelet factor 4 and serotonin in plasma samples
Related Links
- In a study of 16 diabetic patients, high cholesterol and high beta-thromboglobulin levels, pantethine significantly reduced beta-thromboglobulin, triglycerides, total cholesterol and apo levels with 600 mg for three months and 1200 mg ...
- Removal of three amino acids from the aminoterminus of CTAP-3 yields Beta-Thromboglobulin. CTAP-3 is the predominant form of the protein in platelets. The removal of 11 aminoterminal amino acids from Beta-Thromboglobulin (). ...
Related Pictures
★リンクテーブル★
[★]
- 英
- beta-thromboglobulin
- 関
- β-トロンボグロブリン
[★]
- 英
- beta-thromboglobulin β-thromboglobulin β-TG
[★]
β、ベータ
[★]
[★]
トロンボグロブリン