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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/19 19:36:44」(JST)
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English Journal
- Pharmacokinetic comparisons of bepotastine besilate and bepotastine salicylate in healthy subjects.
- Kim KA, Park JY.Author information Department of Clinical Pharmacology and Toxicology, Anam Hospital, Korea University College of Medicine, 126-1, 5-Ga, Anam-dong, Sungbuk-Gu, Seoul, 136-705, Korea.AbstractBACKGROUND AND OBJECTIVE: Bepotastine is a second-generation histamine H(1) receptor antagonist that is indicated in allergic rhinitis, urticaria, and pruritus associated with skin disease. The aim of the present study was to compare the pharmacokinetics of two different bepotastine formulations [bepotastine besilate 10 mg (reference) and bepotastine salicylate 9.64 mg (test)], both containing 7.11 mg bepotastine base, to satisfy regulatory requirements for marketing.
- Clinical drug investigation.Clin Drug Investig.2013 Dec;33(12):913-9. doi: 10.1007/s40261-013-0140-7.
- BACKGROUND AND OBJECTIVE: Bepotastine is a second-generation histamine H(1) receptor antagonist that is indicated in allergic rhinitis, urticaria, and pruritus associated with skin disease. The aim of the present study was to compare the pharmacokinetics of two different bepotastine formulations [be
- PMID 24105252
- Bepotastine besilate for the treatment of pruritus.
- Bielory L, Duttachoudhury S, McMunn A.Author information Rutgers University/Robert Wood Johnson University Hospital , New Brunswick, NJ 07081 , USA +1 973 912 9817 ; +1 206 333 1884 ; Bielory@Rutgers.edu.AbstractINTRODUCTION: Bepotastine besilate 1.5% is a newly approved second-generation topical antihistamine indicated for the pruritus associated with allergic conjunctivitis. In Japan, the oral formulation is approved to manage pruritus associated with allergic rhinitis and urticaria.
- Expert opinion on pharmacotherapy.Expert Opin Pharmacother.2013 Dec;14(18):2553-69. doi: 10.1517/14656566.2013.849242. Epub 2013 Nov 5.
- INTRODUCTION: Bepotastine besilate 1.5% is a newly approved second-generation topical antihistamine indicated for the pruritus associated with allergic conjunctivitis. In Japan, the oral formulation is approved to manage pruritus associated with allergic rhinitis and urticaria.AREAS COVERED: Bepotas
- PMID 24191914
- A case of levocetirizine-induced fixed drug eruption and cross-reaction with piperazine derivatives.
- Kim MY, Jo EJ, Chang YS, Cho SH, Min KU, Kim SH.Author information Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, Korea.AbstractFixed drug eruption is an uncommon adverse drug reaction caused by delayed cell-mediated hypersensitivity. Levocetirizine is an active (R)-enatiomer of cetirizine and there have been a few reports of fixed drug eruption related to these antihistamines. We experienced a case of levocetirizine-induced fixed drug eruption and cross-reaction with other piperazine derivatives confirmed by patch test. A 73-year-old female patient presented with recurrent generalized itching, cutaneous bullae formation, rash and multiple pigmentation at fixed sites after taking drugs for common cold. She took bepotastine besilate (Talion®) and levocetirizine (Xyzal®) as antihistamine. She took acetaminophen, pseudoephedrine 60 mg / triprolidine 2.5 mg (Actifed®), dihydrocodeinebitartrate 5 mg / di-methylephedrine hydrochloride 17.5 mg / chlorpheniramine maleate 1.5 mg / guaifenesin 50 mg (Codening®) and aluminium hydroxide 200 mg / magnesium carbonate 120 mg (Antad®) at the same time. Patch test was done with suspected drugs and the result was positive with levocetirizine. We additionally performed patch test for other antihistamines such as cetirizine, hydroxyzine, fexofenadine and loratadine. Piperazine derivatives (cetirizine and hydroxyzine) were positive, but piperidine derivatives (fexofenadine and loratadine) were negative to patch test. There was no adverse drug reaction when she was challenged with fexofenadine. We report a case of levocetirizine-induced fixed drug eruption confirmed by patch test. Cross-reactions were only observed in the piperazine derivatives and piperidine antihistamine was tolerant to the patient.
- Asia Pacific allergy.Asia Pac Allergy.2013 Oct;3(4):281-4. doi: 10.5415/apallergy.2013.3.4.281. Epub 2013 Oct 31.
- Fixed drug eruption is an uncommon adverse drug reaction caused by delayed cell-mediated hypersensitivity. Levocetirizine is an active (R)-enatiomer of cetirizine and there have been a few reports of fixed drug eruption related to these antihistamines. We experienced a case of levocetirizine-induced
- PMID 24260733
Japanese Journal
- イルベサルタン/アムロジピン配合錠(アイミクス^【○!R】配合錠) の薬理作用および臨床効果
- 森 雅哉,高橋 紫乃
- 日本薬理學雜誌 = Folia pharmacologica Japonica 142(1), 39-46, 2013-07-01
- NAID 10031185427
- 臨床 新薬レビュー イルベサルタン/アムロジピンベシル酸塩 Irbesartan/Amlodipine Besilate : アイミクス配合錠LD/HD 大日本住友製薬株式会社 塩野義製薬株式会社
- 有持 潤子
- MD : medical doctor : 明日を創る医療総合誌 10(1), 40-42, 2013-01
- NAID 40019547310
- アイミクス配合錠(イルベサルタン/アムロジピン配合錠)の研究開発
- 森 雅哉,加藤 浩
- 住友化学 : 技術誌, 63-69, 2013
- NAID 40019777280
Related Links
- e-world in your hands (STAR-LIN Herb Corp.,USA) 海外の個人輸入・情報サイトです。 検索結果を表示 アムロジピン（Amlodipine） 高血圧や狭心症の治療に 一般名：アムロジピンベシル酸塩(Amlodipine Besilate)
- Products Containing Amlodipine Besilate January 12, 2016 Non-proprietary name a. Amlodipine Besilate b. Azilsartan/Amlodipine Besilate c. Aliskiren Fumarate/Amlodipine Besilate d. Irbesartan/Amlodipine Besilate g. Valsartan ...
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★リンクテーブル★
| リンク元 | 「besylate」「ベシル酸」 |
| 拡張検索 | 「bepotastine besilate」「calcium dobesilate」 |
「besylate」
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- besilate
「ベシル酸」
「bepotastine besilate」
- ベシル酸ベ・タスチン