WordNet

a white metallic element that burns with a brilliant light; the fifth most abundant element in the earths crust; an important component of most plants and animals (同)Ca, atomic number 20

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/09/28 02:41:48」(JST)

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1. 下肢慢性静脈疾患の内科的マネージメントmedical management of lower extremity chronic venous disease [show details]
…origin including flavonoids, rutosides, and other less studied agents such as aminaphthone, calcium dobesilate, Centella asiatica (gotu kola), naftazone, and chromocarbe . Most venoactive drugs have been…
2. 家庭や診療所で行う痔核の治療home and office treatment of symptomatic hemorrhoids [show details]
…exceptions. There is high-quality evidence that phlebotonics (eg, flavonoid, hydroxyethylrutoside, calcium dobesilate) can improve hemorrhoid symptoms such as itch and bleeding. The use of phlebotonics for hemorrhoids …
3. 薬剤誘発性の好中球減少および無顆粒球症drug induced neutropenia and agranulocytosis [show details]
…per million users following 10 days of exposure) of 10.1, 3.6, and 1.2, respectively. Calcium dobesilate (Doxium), a veno-tonic drug widely prescribed in Europe, Latin America, Asia, and the Middle East…
4. 糖尿病性網膜症：予防および治療diabetic retinopathy prevention and treatment [show details]
5. うっ滞性皮膚炎stasis dermatitis [show details]
…venoactive or phlebotonic drugs (eg, hydroxyethylrutoside, escin [horse chestnut extract], calcium dobesilate), flavonoids (eg, diosmin and hesperidin, diosmiplex), or pentoxifylline Ablation therapy…

Pereira de Godoy JM1, Pereira de Godoy HJ2, Pereira de Godoy LM3, Guerreiro Godoy MF4.
Journal of clinical medicine.J Clin Med.2017 Dec 25;7(1). pii: E2. doi: 10.3390/jcm7010002.
PMID 29295565

Tang Wang Ming Mu Granule Attenuates Diabetic Retinopathy in Type 2 Diabetes Rats.

Chen M1,2,3, Lv H3, Gan J2, Ren J2, Liu J2.
Frontiers in physiology.Front Physiol.2017 Dec 19;8:1065. doi: 10.3389/fphys.2017.01065. eCollection 2017.
PMID 29311988

Calcium dobesilate may alleviate diabetes‑induced endothelial dysfunction and inflammation.

Zhou Y1, Yuan J1, Qi C1, Shao X1, Mou S1, Ni Z1.
Molecular medicine reports.Mol Med Rep.2017 Dec;16(6):8635-8642. doi: 10.3892/mmr.2017.7740. Epub 2017 Oct 9.
PMID 29039485

Calcium Dobesilate (Cd) in Pigmented Purpuric Dermatosis (PPD) : A Pilot Evaluation

Clinical evaluation of the efficacy and safety of calcium dobesilate in patients with chronic venous insufficiency of the lower limbs

Determination of calcium dobesilate in human plasma using ion-pairing extraction and high-performance liquid chromatography

Journal of chromatography. B, Biomedical sciences and applications 755(1), 245-251, 2001-05-05
NAID 10012245105

Calcium dobesilate
Systematic (IUPAC) name
	calcium 2,5-dihydroxybenzenesulfonate
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
ATC code	C05BX01 (WHO)
PubChem	CID 29963
ChemSpider	27837
UNII	5921X1560Q
Chemical data
Formula	Ca(C6H5O5S)2
Molar mass	418.4098 g/mol
	SMILES [Ca+2].O=S([O-])(=O)c1cc(O)ccc1O.[O-]S(=O)(=O)c1cc(O)ccc1O ;
	InChI InChI=1S/2C6H6O5S.Ca/c27-4-1-2-5(8)6(3-4)12(9,10)11;/h21-3,7-8H,(H,9,10,11);/q;;+2/p-2 ; Key:QGNBTYAQAPLTMX-UHFFFAOYSA-L ;
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