同: Benadryl
関: Diphenhydramine

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/10/05 10:17:23」(JST)

wiki en

Benadryl (diphenhydramine) is a brand name allergy medicine marketed over-the-counter by Johnson & Johnson subsidiary McNeil Consumer Healthcare. Prior to 2007, Benadryl was marketed by Pfizer Consumer Healthcare.^[1]^[2] Benadryl was invented by George Rieveschl and first made publicly available through prescription in 1946.^[3]

Benadryl contains one of several antihistamines and is used for the temporary relief of seasonal and perennial allergy symptoms. Benadryl is available for oral or topical use.

In the United States and Canada, Benadryl products contain the first-generation antihistamine diphenhydramine. In the United Kingdom, Benadryl products contain either the second-generation non-sedating antihistamine acrivastine (marketed as Benadryl Allergy Relief, with a suggested efficacy duration of eight hours) or the long acting antihistamine cetirizine (marketed as Benadryl One a Day Relief). Benadryl products are marketed in Australia and New Zealand by Johnson & Johnson Pacific. They are marketed as cough medicines and do not contain any antihistamine. Each 5 mL of Benadryl Chesty Cough & Nasal Congestion contains 100 mg of guaiphenesin (an expectorant) and 30 mg of pseudoephedrine hydrochloride as the active ingredients ^[4]

References

^ "Johnson & Johnson to Acquire Pfizer Consumer Healthcare" (Press release). Johnson & Johnson. June 26, 2006. http://www.investor.jnj.com/releaseDetail.cfm?releaseid=201875. Retrieved November 19, 2009.
^ "Johnson & Johnson Completes Acquisition Of Pfizer Consumer Healthcare" (Press release). Johnson & Johnson. December 20, 2006. http://www.investor.jnj.com/releaseDetail.cfm?releaseid=223093. Retrieved November 19, 2009.
^ Ohio History central: Benadryl; accessed Jan. 5, 2011
^ Benadryl for the Family Chesty Cough & Nasal Congestion Oral Liquid ; accessed Oct. 13, 2011

"Benadryl (Diphenhydramine) Drug Information". RXList. 2009. http://www.rxlist.com/benadryl-drug.htm. Retrieved March 6, 2009.
"Drugs and Human Performance Fact Sheets: Diphenhydramine". National Highway Traffic and Safety Administration. May 6, 2004. http://www.nhtsa.dot.gov/people/injury/research/job185drugs/diphenhydramine.htm. Retrieved March 6, 2009.

External links

Official UK product website
Official US product website
Official Australia & New Zealand product website

This dermatologic drug article is a stub. You can help Wikipedia by expanding it.

This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 緩和ケアにおける不眠症の概要 overview of insomnia in palliative care
2. Pediatric bipolar disorder: Overview of choosing treatment
3. 成人における確定診断を得られていない低血圧やショックの評価および初期アプローチ evaluation of and initial approach to the adult patient with undifferentiated hypotension and shock
4. 不眠症の治療 treatment of insomnia
5. 小児における接触皮膚炎 contact dermatitis in children

English Journal

A multi-omic approach to elucidate low-dose effects of xenobiotics in zebrafish (Danio rerio) larvae.

Huang SS1, Benskin JP2, Veldhoen N3, Chandramouli B4, Butler H4, Helbing CC3, Cosgrove JR4.
Aquatic toxicology (Amsterdam, Netherlands).Aquat Toxicol.2017 Jan;182:102-112. doi: 10.1016/j.aquatox.2016.11.016. Epub 2016 Nov 18.
Regulatory-approved toxicity assays such as the OECD Fish Embryo Toxicity Assay (TG236) allow correlation of chemical exposure to adverse morphological phenotypes. However, these assays are ineffective in assessing sub-lethal (i.e. low-dose) effects, or differentiating between similar phenotypes ind
PMID 27886581

Premedication Use Before Infliximab Administration: A Cross-sectional Analysis.

Picoraro J1, Winberry G, Siegel CA, El-Matary W, Moses J, Grossman A, Park KT.
Inflammatory bowel diseases.Inflamm Bowel Dis.2017 Jan;23(1):174-180. doi: 10.1097/MIB.0000000000001002.
BACKGROUND: Premedications are commonly given to patients with inflammatory bowel disease before intravenous infliximab administration. We aimed to (1) describe practice variability; and (2) determine clinician rationale for premedicating patients with inflammatory bowel disease before infliximab ad
PMID 28002131

Co-amorphous Formation Induced by Combination of Tranilast and Diphenhydramine Hydrochloride.

Ueda H1, Kadota K2, Imono M1, Ito T2, Kunita A2, Tozuka Y3.
Journal of pharmaceutical sciences.J Pharm Sci.2017 Jan;106(1):123-128. doi: 10.1016/j.xphs.2016.07.009. Epub 2016 Aug 15.
In this study, we investigated the formation of a co-amorphous system of tranilast (TRL) and diphenhydramine hydrochloride (DPH), which are drugs used for treating allergies and inflammation. The crystallization from undercooled melts of the drugs and drug mixtures was evaluated by thermal analysis.
PMID 27539557

Japanese Journal

ＳＡＲＴストレス（反復寒冷ストレス）マウスの摘出小腸におけるアセチルコリン反応性減弱についての一考察

日本薬理学雑誌 75(1), 33-44, 1979
NAID 130000759017

小児脳波検査のミニマム基準に関する検討

脳と発達 9(2), 94-103, 1977
NAID 130004184277

腐敗アサリ貝の化学的・薬理学的研究

日本薬理学雑誌 66(3), 304-315, 1970
NAID 130000757417

Related Pictures

Benadryl Allergy Liqui-Gels (Johnson BENADRYL ALLERGY LIQUID (diphenhydramine Benadryl Ultratab Tablets Allergy Medicine Benadryl Allergy Medicine benadryl for canker sore swelling Benadryl Allergy Relief 48 Count Kapgels Benadryl Child Cherry Allergy Syrup, 8 Fl BENADRYL Children's Allergy Liquid Bubble