atypia

• n.

• 異型性

WordNet

1. not representative of a group, class, or type; "a group that is atypical of the target audience"; "a class of atypical mosses"; "atypical behavior is not the accepted type of response that we expect from children" (同)untypical
2. deviating from normal expectations; somewhat odd, strange, or abnormal; "these days large families are atypical"; "atypical clinical findings"; "atypical pneumonia"; "highly irregular behavior" (同)irregular

PrepTutorEJDIC

1. 型にはまらない,異常な

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/09/04 12:23:57」(JST)

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[Wiki en表示]

Atypia is a pathologic term for a structural abnormality in a cell, i.e. it is used to describe atypical cells.

Atypia: Etymology: Gk, a + typos, without type; a condition of being irregular or nonstandard.

It may or may not be a precancerous indication associated with later malignancy, but the level of appropriate concern is highly dependent on the context with which it is diagnosed.

Atypia can be caused by an infection or irritation if diagnosed in a Pap smear, for example. In the uterus it is more likely to be precancerous. For example, already differentiated, specialised cells such as epithelia displaying "cellular atypia" are far less likely to become problematic [cancerous/ malignant] than are myeloid progeniotor cells of the immune system. The 'further back' in an already specialised, differentiated cell's lineage, the more problematic cellular atypia is likely to be. This is due to the conferring of such atypia to progeny-cells further down the lineage of that cell type.

The term atypia is also used dermatologically and can be a precursor to melanoma.

The related concept of dysplasia refers to an abnormality of development, and includes abnormalities on larger, histopathologic, scales.

References

UpToDate Contents

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• 1. 異型および上皮内小葉癌：乳癌のハイリスク病変 atypia and lobular carcinoma in situ high risk lesions of the breast
• 2. 非定型母斑（異形成母斑） atypical dysplastic nevi
• 3. 甲状腺生検 thyroid biopsy
• 4. 良性乳房疾患の概要 overview of benign breast disease
• 5. 子宮内膜増殖症のマネージメント management of endometrial hyperplasia

English Journal

• Epstein-barr virus-positive pleural effusion: clinical features, cytomorphologic characteristics, and flow cytometric immunophenotyping.

• Takei H1, Mody D2.
• American journal of clinical pathology.Am J Clin Pathol.2014 Dec;142(6):788-94. doi: 10.1309/AJCP3C3BVARTZZWX.
• OBJECTIVES: The etiology of pleural effusions (PEs) varies, and a percentage of PEs remains unexplained despite an intensive workup. One previous study documented a high prevalence of Epstein-Barr virus (EBV)-DNA in unselected and unexplained PEs. Our aim is to characterize the clinical and cytomorp
• PMID 25389332

• Succinate Dehydrogenase (SDH)-deficient Renal Carcinoma: A Morphologically Distinct Entity: A Clinicopathologic Series of 36 Tumors From 27 Patients.

• Gill AJ1, Hes O, Papathomas T, Sedivcová M, Tan PH, Agaimy A, Andresen PA, Kedziora A, Clarkson A, Toon CW, Sioson L, Watson N, Chou A, Paik J, Clifton-Bligh RJ, Robinson BG, Benn DE, Hills K, Maclean F, Niemeijer ND, Vlatkovic L, Hartmann A, Corssmit EP, van Leenders GJ, Przybycin C, McKenney JK, Magi-Galluzzi C, Yilmaz A, Yu D, Nicoll KD, Yong JL, Sibony M, Yakirevich E, Fleming S, Chow CW, Miettinen M, Michal M, Trpkov K.
• The American journal of surgical pathology.Am J Surg Pathol.2014 Dec;38(12):1588-602. doi: 10.1097/PAS.0000000000000292.
• Succinate dehydrogenase (SDH)-deficient renal carcinoma has been accepted as a provisional entity in the 2013 International Society of Urological Pathology Vancouver Classification. To further define its morphologic and clinical features, we studied a multi-institutional cohort of 36 SDH-deficient r
• PMID 25025441

• Myofibromas with atypical features: expanding the morphologic spectrum of a benign entity.

• Linos K1, Carter JM, Gardner JM, Folpe AL, Weiss SW, Edgar MA.
• The American journal of surgical pathology.Am J Surg Pathol.2014 Dec;38(12):1649-54. doi: 10.1097/PAS.0000000000000270.
• Typical myofibromas are biphasic tumors composed of a central zone of immature spindled to rounded cells arranged in a pericytic pattern and a peripheral zone of myoid nodules. Central necrosis is occasionally seen. A small but undefined subset of myofibromas displays atypical features that may lead
• PMID 24921644

Japanese Journal

• 子宮体部原発類内膜腺癌(G1)および子宮内膜増殖症の細胞学的検討 : 構造異型および構成細胞の観察を中心に

• 松井 成明,梶原 博,涌井 架奈子,伊藤 仁,北村 隆司,光谷 俊幸,村上 優,佐藤 慎吉,安田 政実,中村 直哉
• 日本臨床細胞学会雑誌 50(5), 261-269, 2011-09-22
• NAID 10029460055

• 非浸潤性乳管癌および乳管内病変の病理診断 : 最近の話題も含めて

• 森谷 卓也,鹿股 直樹,小塚 祐司
• 診断病理 : Japanese journal of diagnostic pathology 28(2), 79-89, 2011-04-28
• NAID 10029411640

Related Links

• Atypia - Wikipedia, the free encyclopedia

Atypia is a clinical term for abnormality in a cell. The term is medical jargon for an atypical cell. Atypia: Etymology: Gk, a + typos, without type; a condition of being irregular or nonstandard. It may or may not be a precancerous indication ...

Related Pictures

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★リンクテーブル★

リンク元	「異型性」「異型」「atypical」「非定型性」「nonclassic」

「異型性」

　　[★]

英

atypia,

関

多形性

• 組織や細胞の形態が正常と異なることを指す。

• 構造異型：細胞の配列の乱れや極性の消失などの組織構築の異型性
• 細胞異型：細胞や核の大きさ、形、染色性などの正常からの偏りを表す異型性

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英

heterogametic sex

関

同型性

「異型」

　　[★]

英

atypism、atypical、variant、off-type、meta

関

オフ型、異なる、非定型、非定型性、非定型的、変異、変異株、変異体、変種、メタ、変異形、バリアント、アティピア atypia、異型性

「atypical」

　　[★]

• adj.

• 非定型の, 非定型的な, 非定型性の, 異型の

関

atypia、atypically、atypism、meta、nonclassic、off-type、variant

　 　 　

「非定型性」

　　[★]

英

atypia、atypical、nonclassic

関

異型、非古典的、非定型、非定型的

「nonclassic」

　　[★]

• 非古典的な、非定型性の

関

atypia、atypical、nonclassical