プリン塩基のない、脱プリン塩基の
English Journal
- The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once.
- Tsutakawa SE1, Lafrance-Vanasse J1, Tainer JA2.
- DNA repair.DNA Repair (Amst).2014 Jul;19:95-107. doi: 10.1016/j.dnarep.2014.03.022. Epub 2014 Apr 19.
- To avoid genome instability, DNA repair nucleases must precisely target the correct damaged substrate before they are licensed to incise. Damage identification is a challenge for all DNA damage response proteins, but especially for nucleases that cut the DNA and necessarily create a cleaved DNA repa
- PMID 24754999
- NAD attenuates oxidative DNA damages induced by amyloid beta-peptide in primary rat cortical neurons.
- Wu MF1, Yin JH, Hwang CS, Tang CM, Yang DI.
- Free radical research.Free Radic Res.2014 Jul;48(7):794-805. doi: 10.3109/10715762.2014.907889. Epub 2014 Apr 22.
- Abstract One major pathological hallmark of Alzheimer's disease (AD) is accumulation of senile plaques in patients' brains, mainly composed of amyloid beta-peptide (Aβ). Nicotinamide adenine dinucleotide (NAD) has emerged as a common mediator regulating energy metabolism, mitochondrial function, ag
- PMID 24678962
- Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair.
- Wu XY1, Chen C1, Yao XQ1, Cao QH1, Xu Z1, Li WS1, Liu FK1, Li G2.
- Molecular medicine reports.Mol Med Rep.2014 Jul;10(1):486-90. doi: 10.3892/mmr.2014.2185. Epub 2014 Apr 24.
- The present study aimed to examine the effects of recombinant human growth hormone (rhGH) on the sensitivity of a colorectal cancer cell line to radiotherapy, and to investigate its association with DNA damage and repair. Flow cytometry and immunofluorescence were employed to detect growth hormone r
- PMID 24788673
Japanese Journal
- 4-Hydroxyestradiol Induces γ-H2AX in the Presence of an Inhibitor of Catechol-O-methyltransferase in Human Breast Cancer MCF-7 Cells
- Yamazaki Shunsuke,Sakakibara Hiroyuki,Takemura Hitomi [他],SHIMOI Kayoko
- Genes and environment : the official journal of the Japanese Environmental Mutagen Society 34(3), 129-135, 2012-08-20
- NAID 10030688139
- 9J-12 極低周波変動磁場と化学物質の複合曝露によるA172細胞内APサイト形成の増幅効果(OS-11(3) 細胞・生体分子のバイオメカニクス(2))
- 小山 眞,村越 道生,櫻井 智徳,宮越 順二,和田 仁
- バイオエンジニアリング講演会講演論文集 2010(23), 497-498, 2011-01-07
- NAID 110008744240
- Perfluorooctanoic acid (PFOA) but not perfluorooctane sulfonate (PFOS) showed DNA damage in comet assay on Paramecium caudatum
- Kawamoto Kosuke,Oashi Takahiro,Oami Kazunori [他],LIU Wei,JIN Yihe,SAITO Norimitsu,SATO Itaru,TSUDA Shuji
- Journal of toxicological sciences 35(6), 835-841, 2010-12-01
- … On the other hand, 12 and 24 hr exposure to PFOA (100 µM) increased DNA migration in electrophoresis condition at pH 13, but not at pH 12.1, suggesting that the DNA damage may be alkali labile site (such as apurinic/apyrimidinic (AP) site). …
- NAID 10026963006
Related Links
- In biochemistry and molecular genetics, an AP site (apurinic/apyrimidinic site), also known as an abasic site, is a location in DNA ... It has been estimated that under physiological condition 10,000 apurinic sites may be generated in a cell daily.
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★リンクテーブル★
| リンク元 | 「脱プリン塩基」「プリン塩基のない」 |
| 拡張検索 | 「apurinic-apyrimidinic endonuclease」「apurinic endonuclease」 |