antitoxin

抗毒素 　 　

WordNet

1. an antibody that can neutralize a specific toxin
2. a mixture of toxin and antitoxin used to immunize against a disease

PrepTutorEJDIC

1. 〈C〉抗毒素 / 〈U〉抗毒素血清

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/03 01:11:16」(JST)

wiki en

[Wiki en表示]

An antitoxin is an antibody with the ability to neutralize a specific toxin. Antitoxins are produced by certain animals, plants, and bacteria. Although they are most effective in neutralizing toxins, they can kill bacteria and other microorganisms. Antitoxins are made within organisms, but can be injected into other organisms, including humans. This procedure involves injecting an animal with a safe amount of a particular toxin. Then, the animal’s body makes the antitoxin needed to neutralize the toxin. Later, the blood is withdrawn from the animal. When the antitoxin is obtained from the blood, it is purified and injected into a human or other animal, inducing passive immunity. To prevent serum sickness, it is often best to use antitoxin generated from the same species (e.g. use human antitoxin to treat humans).

See also

• Toxin-antitoxin system
• Vaccination
• The horse named Jim
• Antiserum

References

External links

• http://www.medterms.com/script/main/art.asp?articlekey=2289
• Antitoxins at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. ジフテリアの診断および治療 diagnosis and treatment of diphtheria
• 2. ボツリヌス中毒 botulism
• 3. クロストリジウム・ソルデリによる毒素性ショック症候群 toxic shock syndrome due to clostridium sordellii
• 4. 非神経性の下部尿路症状の治療におけるボツリヌス毒素の使用 use of botulinum toxin for treatment of non neurogenic lower urinary tract conditions
• 5. 7～18歳の小児におけるジフテリア、破傷風、および百日咳ワクチン diphtheria tetanus and pertussis immunization in children 7 through 18 years of age

English Journal

• Detection of endogenous MazF enzymatic activity in Staphylococcus aureus.

• van Rensburg JJ, Hergenrother PJ.SourceDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
• Analytical biochemistry.Anal Biochem.2013 Dec 1;443(1):81-7. doi: 10.1016/j.ab.2013.08.018. Epub 2013 Aug 29.
• The mazEFSa toxin-antitoxin (TA) system is ubiquitous in clinical isolates of Staphylococcus aureus, yet its physiological role is unclear. MazFSa is a sequence-specific endoribonuclease that inhibits the growth of S. aureus and Escherichia coli on ectopic overexpression. MazFSa preferentially cleav
• PMID 23994560

• ICESluvan, a 94-Kilobase Mosaic Integrative Conjugative Element Conferring Interspecies Transfer of VanB-Type Glycopeptide Resistance, a Novel Bacitracin Resistance Locus, and a Toxin-Antitoxin Stabilization System.

• Bjørkeng EK, Hjerde E, Pedersen T, Sundsfjord A, Hegstad K.SourceResearch Group for Host-Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
• Journal of bacteriology.J Bacteriol.2013 Dec;195(23):5381-90. doi: 10.1128/JB.02165-12. Epub 2013 Sep 27.
• A 94-kb integrative conjugative element (ICESluvan) transferable to Enterococcus faecium and Enterococcus faecalis from an animal isolate of Streptococcus lutetiensis consists of a mosaic of genetic fragments from different Gram-positive bacteria. A variant of ICESluvan was confirmed in S. lutetiens
• PMID 24078615

• The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu.

• Castro-Roa D, Garcia-Pino A, De Gieter S, van Nuland NA, Loris R, Zenkin N.Source1] Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, UK. [2].
• Nature chemical biology.Nat Chem Biol.2013 Dec;9(12):811-7. doi: 10.1038/nchembio.1364. Epub 2013 Oct 20.
• Fic proteins are ubiquitous in all of the domains of life and have critical roles in multiple cellular processes through AMPylation of (transfer of AMP to) target proteins. Doc from the doc-phd toxin-antitoxin module is a member of the Fic family and inhibits bacterial translation by an unknown mech
• PMID 24141193

Japanese Journal

• A Case of Tetanus Associated with Dysphagia

• 島谷 美映,宇高 二良,島谷 佳光,千田 いづみ,島田 亜紀,田村 公一,武田 憲昭
• 耳鼻咽喉科臨床 105(6), 571-575, 2012
• … The patient was cured with tetanus antitoxin and antibiotics without any sequelae. …
• NAID 130002141344

• Type A1 but Not Type A2 Botulinum Toxin Decreases the Grip Strength of the Contralateral Foreleg Through Axonal Transport From the Toxin-Treated Foreleg of Rats

• TORII Yasushi,AKAIKE Norio,HARAKAWA Tetsuhiro,KATO Keiko,SUGIMOTO Nakaba,GOTO Yoshitaka,NAKAHIRA Shinji,KOHDA Tomoko,KOZAKI Shunji,KAJI Ryuji,GINNAGA Akihiro
• Journal of pharmacological sciences 117(4), 275-285, 2011-12-20
• … We investigated the route of toxin spread using denervated, colchicine-treated, and antitoxin-treated rats. …
• NAID 10030453790

• Clostridium perfringens 感染患者に対する治療用ウマ抗毒素製剤の存在を知っていますか?

• 一二三 亨,高橋 元秀,諸熊 一則,吉岡 早戸,原口 義座,加藤 宏,小井土 雄一,本間 正人
• 日本集中治療医学会雑誌 = Journal of the Japanese Society of Intensive Care Medicine 17(3), 287-289, 2010-07-01
• NAID 10029382531

Related Links

• Antitoxin

Video on Antitoxin ... Home | Blog Whiteboard Animation: This Website Was Created With: Page: 1 Impressum Site map Disclaimer & Contact Privacy Policy XHTML CSS @ Copyright website All rights reserved.

• Antitoxin | Define Antitoxin at Dictionary.com

antitoxin / ˌæn tɪˈtɒk sɪn, ˌæn ti-/ Show Spelled [an-ti-tok-sin, an-tee-] Show IPA noun 1. a substance, formed in the body, that counteracts a specific toxin. 2. the antibody formed in immunization with a given toxin, used in treating ...

Related Pictures

---

★リンクテーブル★

リンク元	「抗毒素」
拡張検索	「gas gangrene equine-antitoxin」

「抗毒素」

　　[★]

英

antitoxin

関

トキソイド

「gas gangrene equine-antitoxin」

　　[★] ガス壊疽ウマ抗毒素