- 関
- anti-sense RNA、antisense RNA
UpToDate Contents
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English Journal
- Rescue of cardiomyopathy through U7snRNA-mediated exon skipping in Mybpc3-targeted knock-in mice.
- Gedicke-Hornung C, Behrens-Gawlik V, Reischmann S, Geertz B, Stimpel D, Weinberger F, Schlossarek S, Précigout G, Braren I, Eschenhagen T, Mearini G, Lorain S, Voit T, Dreyfus PA, Garcia L, Carrier L.SourceDepartment of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany.
- EMBO molecular medicine.EMBO Mol Med.2013 Jul;5(7):1128-45. doi: 10.1002/emmm.201202168. Epub 2013 May 29.
- Exon skipping mediated by antisense oligoribonucleotides (AON) is a promising therapeutic approach for genetic disorders, but has not yet been evaluated for cardiac diseases. We investigated the feasibility and efficacy of viral-mediated AON transfer in a Mybpc3-targeted knock-in (KI) mouse model of
- PMID 23716398
- The effect of telomerase activity on vascular smooth muscle cell proliferation in type 2 diabetes in vivo and in vitro.
- Sun X, Han F, Yi J, Hou N, Cao Z.SourceDepartment of Endocrinology, The Affiliated Hospital of Weifang Medical University, Weifang, Shangdong 261031, PR China. sxdfriend@sina.com
- Molecular medicine reports.Mol Med Rep.2013 May;7(5):1636-40. doi: 10.3892/mmr.2013.1350. Epub 2013 Feb 28.
- Serious complications as a result of type 2 diabetes mellitus (T2DM) are becoming a major health concern. In the present study, it was hypothesized that telomerase activity is upregulated in vascular smooth muscle cells (VSMCs) during proliferation in T2DM and that the application of telomerase inh
- PMID 23450462
- Potent and selective inhibition of A-to-I RNA editing with 2'-O-methyl/locked nucleic acid-containing antisense oligoribonucleotides.
- Mizrahi RA, Schirle NT, Beal PA.SourceDepartment of Chemistry, University of California, Davis, CA 95616, USA.
- ACS chemical biology.ACS Chem Biol.2013 Apr 19;8(4):832-9. doi: 10.1021/cb300692k. Epub 2013 Feb 21.
- ADARs (adenosine deaminases acting on RNA) are RNA editing enzymes that bind double helical RNAs and deaminate select adenosines (A). The product inosine (I) is read during translation as guanosine (G), so such changes can alter codon meaning. ADAR-catalyzed A to I changes occur in coding sequences
- PMID 23394403
Related Links
- 英語をクリック → Antisense Oligoribonucleotide との組み合わせでEntrez を検索 ジストロフィン (Dystrophin); デュシェンヌ型筋ジストロフィー (Duchenne Muscular Dystrophy); RNA安定性 (RNA Stability); 選択的スプライシング ); (); (); ...
- Oligoribonucleotide, Antisense (n.) (MeSH) D13.150.480.645, D13.150.650.640, D13.444.600.150.640.645, D13.444.600.150.760.640, D13.444.735.150.640, D13.695.578.424.480.645, D27.720.470.530.600.150.640.645, D27.720.470 ...
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★リンクテーブル★
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アンチセンスRNA
- 関
- anti-sense RNA、antisense oligoribonucleotide
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- 関
- antisense oligoribonucleotide、antisense RNA
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- 英
- antisense oligoribonucleotide
- 関
- アンチセンスRNA
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オリゴリボヌクレオチド、オリゴRNA
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アンチセンス
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- a.s.、AS