WordNet

any of several vasoconstrictor substances (trade name Hypertensin) that cause narrowing of blood vessels (同)angiotonin, Hypertensin
any organic compound containing the group -CONH2

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease.

Wang SJ1, Laulederkind SJ2, Hayman GT2, Petri V2, Liu W2, Smith JR2, Nigam R2, Dwinell MR2, Shimoyama M3.
Database : the journal of biological databases and curation.Database (Oxford).2015 Jan 28;2015. pii: bau128. doi: 10.1093/database/bau128. Print 2015.
Rats have been used extensively as animal models to study physiological and pathological processes involved in human diseases. Numerous rat strains have been selectively bred for certain biological traits related to specific medical interests. Recently, the Rat Genome Database (http://rgd.mcw.edu) h
PMID 25632109

Local uterine Ang-(1-7) infusion augments the expression of cannabinoid receptors and differentially alters endocannabinoid metabolizing enzymes in the decidualized uterus of pseudopregnant rats.

Brosnihan KB1, Pulgar VM, Gallagher PE, Neves LA, Yamaleyeva LM.
Reproductive biology and endocrinology : RB&E.Reprod Biol Endocrinol.2015 Jan 17;13:5. doi: 10.1186/1477-7827-13-5.
BACKGROUND: Endocannabinoids (ECs) are important contributors to implantation and decidualization and are suppressed in early pregnancy. Elevated levels of anandamide (AEA), the endogenous ligand for the CB1 and CB2 receptors (R), interfere with receptivity of the blastocyst. Ang-(1-7) is down-regul
PMID 25596750

Inhibitory effect of D3 dopamine receptor on migration of vascular smooth muscle cells induced by synergistic effect of angiotensin II and aldosterone.

Li Y1, Wang N, Chen C, He D, Yang J, Zeng C.
Clinical and experimental hypertension (New York, N.Y. : 1993).Clin Exp Hypertens.2015;37(4):288-93. doi: 10.3109/10641963.2014.960971. Epub 2014 Dec 12.
OBJECTIVE: The abnormal migration of vascular smooth muscle cells (VSMCs) has been implicated to contribute to lesion formation in the adult vasculature. The renin-angiotensin-aldosterone system (RAAS) is intensively involved in the pathogenesis of a variety of cardiovascular diseases. There are inc
PMID 25496286

長尾善光
藥學雜誌 122(1), 1-27, 2002-01-01
… σ-symmetric bifunctional molecules, dipole-dipole repulsion, active amide structures, latent active species, orbital-orbital interactions, nonbonded interactions, strained structures, allenic structures, etc. … Evaluation and molecular design of the seed and model compounds for angiotensin II receptor antagonists, tumor inhibitors, and antibiotics have been investigated on the basis of QRSA and/or nonbonded S…X(X=O, N, S, halogens)interaction concepts. …
NAID 110003648414

pH-Dependent Coordination of Metal-Lisinopril Complex Investigated by Attenuated Total Reflection/Fourier Transform Infrared Spectroscopy

Wang Shun-Li,Chuang Chi-Hsiang,Lin Shan-Yang
Chemical & pharmaceutical bulletin 50(1), 78-82, 2002-01-01
… In order to simulate the in vivo binding behavior of angiotensin-converting enzyme(ACE)inhibitors to the zinc-containing active center of ACE, the in vitro interaction between lisinopril and zinc or nickel ions was investigated in aqueous solutions of different pH by using attenuated total reflection(ATR)/Fourier transform infrared(FT-IR)spectroscopy with second-derivative IR spectral analysis. …
NAID 110003616132

Purification and Characterization of Myonase from X-Chromosome Linked Muscular Dystrophic Mouse Skeletal Muscle.

Hori Shinichiro,Ohtani Sachiko,Hori Chiyo,Nokihara Kiyoshi
The Journal of Biochemistry 123(4), 650-658, 1998
… Myonase has chymotrypsin-like activities and hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. … Myonase preferentially hydrolyzes the Tyr4-Ile5 bond of angiotensin I and the Phe20-A1a21 bond of amyloid β-protein, and it is less active towards the Phe8-His9 bond of angiotensin I and the Phe4-Ala5 and Tyr10-Glu11 bonds of amyloid β-protein. …
NAID 130003533413