関: angiotensin amide

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/17 21:14:54」(JST)

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Angiotensinamide (INN; BAN and USAN angiotensin amide) is a potent vasoconstrictor used as a cardiac stimulant. It is a derivative of angiotensin II.

English Journal

PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease.

Wang SJ1, Laulederkind SJ2, Hayman GT2, Petri V2, Liu W2, Smith JR2, Nigam R2, Dwinell MR2, Shimoyama M3.
Database : the journal of biological databases and curation.Database (Oxford).2015 Jan 28;2015. pii: bau128. doi: 10.1093/database/bau128. Print 2015.
Rats have been used extensively as animal models to study physiological and pathological processes involved in human diseases. Numerous rat strains have been selectively bred for certain biological traits related to specific medical interests. Recently, the Rat Genome Database (http://rgd.mcw.edu) h
PMID 25632109

Local uterine Ang-(1-7) infusion augments the expression of cannabinoid receptors and differentially alters endocannabinoid metabolizing enzymes in the decidualized uterus of pseudopregnant rats.

Brosnihan KB1, Pulgar VM, Gallagher PE, Neves LA, Yamaleyeva LM.
Reproductive biology and endocrinology : RB&E.Reprod Biol Endocrinol.2015 Jan 17;13:5. doi: 10.1186/1477-7827-13-5.
BACKGROUND: Endocannabinoids (ECs) are important contributors to implantation and decidualization and are suppressed in early pregnancy. Elevated levels of anandamide (AEA), the endogenous ligand for the CB1 and CB2 receptors (R), interfere with receptivity of the blastocyst. Ang-(1-7) is down-regul
PMID 25596750

Inhibitory effect of D3 dopamine receptor on migration of vascular smooth muscle cells induced by synergistic effect of angiotensin II and aldosterone.

Li Y1, Wang N, Chen C, He D, Yang J, Zeng C.
Clinical and experimental hypertension (New York, N.Y. : 1993).Clin Exp Hypertens.2015;37(4):288-93. doi: 10.3109/10641963.2014.960971. Epub 2014 Dec 12.
OBJECTIVE: The abnormal migration of vascular smooth muscle cells (VSMCs) has been implicated to contribute to lesion formation in the adult vasculature. The renin-angiotensin-aldosterone system (RAAS) is intensively involved in the pathogenesis of a variety of cardiovascular diseases. There are inc
PMID 25496286

Japanese Journal

レーザードップラー血流計による内耳血流動的変化の観察

中島徹,牧本一男,川上理郎,野井理,福瀬信也,高橋宏明
Ear Research Japan 18, 226-228, 1987
… Present studies on the dynamic changes of cochlear blood flow included following experiments: clamping of the right carotid artery, temporary asphyxia, terminal asphyxia and Angiotensinamide injection through the femoral artery using a microinjector. …
NAID 130004355663

FurosemideのEP低下作用に対する血圧の影響について

大村正樹,八木伸也,加納直行,牧本一男
Ear Research Japan 14(1), 136-138, 1983
… To observe the effect of acute hypertension on EP decreasing action of furosemide, the present experiment was performed on guinea pigs using angiotensinamide. … In one group, 30 or 40 mg/kg of furosemide was injected, while in the other, angiotensinamide was continuously injected through a microinjector prior to the furosemide (30 or 40 mg/kg) injection. …
NAID 130004355098

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リンク元	「angiotensin amide」「アンギオテンシンアミド」「アンジオテンシンアミド」

「angiotensin amide」

Angiotensinamide
Systematic (IUPAC) name
	2-[(1-{2-[2-(2-{2-[2-(2-amino-3-carbamoylpropanamido)-5-[(diaminomethylidene)amino]pentanamido]-3-methylbutanamido}-3-(4-hydroxyphenyl)propanamido)-3-methylbutanamido]-3-(1H-imidazol-5-yl)propanoyl}pyrrolidin-2-yl)formamido]-3-phenylpropanoic acid
Clinical data
Routes of; administration	Intravenous infusion
Identifiers
CAS Registry Number	53-73-6
ATC code	C01CX06
PubChem	CID: 10351092
ChemSpider	8526544
UNII	7WAL1X78KV
KEGG	D02939
ChEMBL	CHEMBL409803
Chemical data
Formula	C49H70N14O11
Molecular mass	1031.17 g/mol
	SMILES O=C(N)C[C@H](N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)CCC2)Cc3cncn3)C(C)C)Cc4ccc(O)cc4)C(C)C)CCC/N=C(\N)N ;
	InChI InChI=1S/C49H70N14O11/c1-26(2)39(61-42(67)33(12-8-18-55-49(52)53)57-41(66)32(50)23-38(51)65)45(70)58-34(20-29-14-16-31(64)17-15-29)43(68)62-40(27(3)4)46(71)59-35(22-30-24-54-25-56-30)47(72)63-19-9-13-37(63)44(69)60-36(48(73)74)21-28-10-6-5-7-11-28/h5-7,10-11,14-17,24-27,32-37,39-40,64H,8-9,12-13,18-23,50H2,1-4H3,(H2,51,65)(H,54,56)(H,57,66)(H,58,70)(H,59,71)(H,60,69)(H,61,67)(H,62,68)(H,73,74)(H4,52,53,55)/t32-,33-,34-,35-,36-,37-,39-,40-/m0/s1 ; Key:JYPVVOOBQVVUQV-CGHBYZBKSA-N ;
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アンジオテンシンアミド、アンギオテンシンアミド

関: angiotensinamide

「アンギオテンシンアミド」

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英: angiotensinamide、angiotensin amide
関: アンジオテンシンアミド

「アンジオテンシンアミド」

　　[★]

英: angiotensinamide、angiotensin amide
関: アンギオテンシンアミド

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angiotensinamide