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English Journal

Microglia activation: one of the checkpoints in the CNS inflammation caused by Angiostrongylus cantonensis infection in rodent model.

Wei J1, Wu F, He A, Zeng X, Ouyang LS, Liu MS, Zheng HQ, Lei WL, Wu ZD, Lv ZY.
Parasitology research.Parasitol Res.2015 May 24. [Epub ahead of print]
Angiostrongylus cantonensis (A. cantonensis) is a rodent nematode. Adult worms of A. cantonensis live in the pulmonary arteries of rats; humans are non-permissive hosts like the mice. The larva cannot develop into an adult worm and only causes serious eosinophilic meningitis or meningo-encephalitis
PMID 26002828

Fibronectin changes in eosinophilic meningitis with blood-CSF barrier disruption.

Shyu LY1, Hu ME2, Chou CH3, Chen KM1, Chiu PS3, Lai SC4.
Experimental parasitology.Exp Parasitol.2015 Apr-May;151-152:73-9. doi: 10.1016/j.exppara.2015.02.002. Epub 2015 Feb 7.
Fibronectin, which is present at relatively low levels in healthy central nervous systems (CNS), shows increased levels in meningitis. In this study, fibronectin processing was correlated with the increased permeability of the blood-cerebrospinal fluid (CSF) barrier as well as with the formation of
PMID 25660199

Aghazadeh M1, Jones MK, Aland KV, Reid SA, Traub RJ, McCarthy JS, Lee R.
Vector borne and zoonotic diseases (Larchmont, N.Y.).Vector Borne Zoonotic Dis.2015 Mar;15(3):184-90. doi: 10.1089/vbz.2014.1622.
Despite an apparent increase in cases of angiostrongyliasis in humans and animals in Australia, the epidemiology of infection with the two species of Angiostrongylus that co-exist in this country, namely A. cantonensis and A. mackerrasae, is poorly understood. This knowledge gap is particularly impo
PMID 25793473

Encephalitis Caused by Angiostrongylus cantonensis after Eating Raw Frogs Mixed with Wine as a Health Supplement

Tsai Hung-Chin,Lai Ping-Hong,Sy Cheng-Len,Lee Susan Shin-Jung,Yen Chuan-Min,Wann Shue-Ren,Chen Yao-Shen
Internal Medicine 50(7), 771-774, 2011
… Angiostrongylus cantonensis also known as the rat lungworm, is prevalent in the Pacific Islands and southeast Asia and is the most common cause of eosinophilic meningitis in humans. … cantonensis, they are rarely reported as the infectious source of human angiostrongyliasis. … We report a case of encephalitis caused by Angiostrongylus cantonensis after eating raw frogs mixed with wine as a health supplement. …
NAID 130000650056

Changing Epidemiology of Angiostrongyliasis Cantonensis in Okinawa Prefecture, Japan

CIRCUMOVAL AND CIRCUMLARVAL PRECIPITATE REACTIONS OF ANGIOSTRONGYLUS CANTONENSIS

OKU Yuzaburo,KAMIYA Masao
Japanese journal of veterinary research 32(1), 23-39, 1984-01-31
… Using sera obtained from Angiostrongylus cantonensis-infected or -transferred rats and immunized guinea pigs with A. … cantonensis homogenate, positive circumoval and circumlarval precipitate reactions on living A. … cantonensis at various developmental stages were recognized after incubation at 34℃ for 24hr. … For the immunodiagnosis of angiostrongyliasis, the excellency of the circumoval and circumlarval precipitate reactions was noted. …
NAID 110001077276

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