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English Journal

Stimulation of osteogenesis and angiogenesis of hBMSCs by delivering Si ions and functional drug from mesoporous silica nanospheres.

Shi M1, Zhou Y2, Shao J2, Chen Z2, Song B1, Chang J3, Wu C4, Xiao Y2.
Acta biomaterialia.Acta Biomater.2015 Jul 15;21:178-89. doi: 10.1016/j.actbio.2015.04.019. Epub 2015 Apr 21.
Multifunctional bioactive materials with the ability to stimulate osteogenesis and angiogenesis of stem cells play an important role in the regeneration of bone defects. However, how to develop such biomaterials remains a significant challenge. In this study, we prepared mesoporous silica nanosphere
PMID 25910640

Conditioned medium from umbilical cord mesenchymal stem cells induces migration and angiogenesis.

Shen C1, Lie P2, Miao T3, Yu M1, Lu Q4, Feng T1, Li J4, Zu T1, Liu X4, Li H1.
Molecular medicine reports.Mol Med Rep.2015 Jul;12(1):20-30. doi: 10.3892/mmr.2015.3409. Epub 2015 Mar 4.
Umbilical cord mesenchymal stem cells (UC‑MSCs) have been suggested as a candidate for various clinical applications, however, major limitations include the lack of organ‑specific accumulation and low survival rates of transplanted cells. In the present study, it was hypothesized that the paracr
PMID 25739039

SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development.

Marks-Bluth J1, Khanna A2, Chandrakanthan V2, Thoms J2, Bee T2, Eich C3, Kang YC2, Knezevic K2, Qiao Q2, Fitch S4, Oxburgh L5, Ottersbach K4, Dzierzak E6, de Bruijn MF7, Pimanda JE8.
Molecular and cellular biology.Mol Cell Biol.2015 Jun 15;35(12):2165-72. doi: 10.1128/MCB.00239-15. Epub 2015 Apr 13.
The bone morphogenetic protein (BMP)/SMAD signaling pathway is a critical regulator of angiogenic sprouting and is involved in vascular development in the embryo. SMAD1 and SMAD5, the core mediators of BMP signaling, are vital for this activity, yet little is known about their transcriptional regula
PMID 25870111

In Vivo Anti-tumor Effects of the Ethanol Extract of Gleditsia sinensis Thorns and Its Active Constituent, Cytochalasin H

Yi Jin-Mu,Kim Jinhee,Park Jong-Shik [他],Lee Jun,Lee You Jin,Hong Jin Tae,Bang Ok-Sun,Kim No Soo
Biological and Pharmaceutical Bulletin 38(6), 909-912, 2015
… We previously reported that an ethanolic extract of Gleditsia sinensis thorns (EEGS) and its active constituent, cytochalasin H, have anti-angiogenic activity in vitro and in vivo via suppression of endothelial cell functions. … These results suggest that EEGS and its active constituent, cytochalasin H, are potential candidates for the development of anti-angiogenic cancer drugs. …
NAID 130005072655

Sato Yasufumi
Journal of Atherosclerosis and Thrombosis 22(4), 327-334, 2015
… The unique features of VASH1 are its anti-angiogenic activity and ability to promote the stress tolerance and survival of ECs. …
NAID 130005066048

Sato Yasufumi
Journal of Atherosclerosis and Thrombosis advpub(0), 2015
… The unique features of VASH1 are its anti-angiogenic activity and ability to promote the stress tolerance and survival of ECs. …
NAID 130004845534