Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2019/06/07 01:05:13」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 尿路上皮（移行上皮）膀胱癌の疫学および危険因子epidemiology and risk factors of urothelial transitional cell carcinoma of the bladder [show details]
…and their precursors or derivatives. Other well-characterized carcinogenic chemicals include 4-aminobiphenyl, 4-nitrobiphenyl, and 2-amino-1-naphthol . The long latent period between exposure and the development …

English Journal

Primary aromatic amines and cancer: Novel mechanistic insights using 4-aminobiphenyl as a model carcinogen.

Wang S, Hanna D, Sugamori KS, Grant DM.
Pharmacology & therapeutics. 2019 May;().
Aromatic amines are an important class of human carcinogens found ubiquitously in our environment. It is estimated that 1 in 8 of all known or suspected human carcinogens is or can be converted into an aromatic amine, making the elucidation of their mechanisms of toxicity a top public health priorit
PMID 31075357

Probing the Effect of Bulky Lesion-Induced Replication Fork Conformational Heterogeneity Using 4-Aminobiphenyl-Modified DNA.

Cai A, Bian K, Chen F, Tang Q, Carley R, Li D, Cho BP.
Molecules (Basel, Switzerland). 2019 Apr;24(8).
Bulky organic carcinogens are activated in vivo and subsequently react with nucleobases of cellular DNA to produce adducts. Some of these DNA adducts exist in multiple conformations that are slowly interconverted to one another. Different conformations have been implicated in different mutagenic and
PMID 31009995

Short-term detection of gastric genotoxicity using the DNA double-strand break marker γ-H2AX.

Okabe A, Kiriyama Y, Suzuki S, Sakurai K, Teramoto A, Kato H, Naiki-Ito A, Tahara S, Takahashi S, Kuroda M, Sugioka A, Tsukamoto T.
Journal of toxicologic pathology. 2019 Apr;32(2)91-99.
DNA damage caused by infection and chronic inflammation or exposure to genotoxic agents is considered an important risk factor of gastric carcinogenesis. In this study, we have evaluated a short-term technique to detect DNA damage response to various chemical carcinogens; it involves visualization
PMID 31092975

Japanese Journal

Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃ　Ｐａｔｈｏｌｏｇｙ

Okabe Asako,Kuroda Makoto,Sugioka Atsushi,Tsukamoto Tetsuya,Kiriyama Yuka,Suzuki Shugo,Sakurai Kouhei,Teramoto Atsushi,Kato Hiroyuki,Naiki-Ito Aya,Tahara Sayumi,Takahashi Satoru
Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃ　Ｐａｔｈｏｌｏｇｙ 32(2), 91-99, 2019
… Six-week-old male rats were intragastrically administered N-methyl-N-nitrosourea (MNU), 3,2'-dimethyl-4-aminobiphenyl (DMAB), dimethylnitrosamine (DMN), and 1,2- dimethylhydrazine (DMH) for 5 days/week for 4 weeks, using corn oil as a vehicle. …
NAID 130007636048

Short-term detection of gastric genotoxicity using the DNA double-strand break marker γ-H2AX

OKABE Asako,KURODA Makoto,SUGIOKA Atsushi,TSUKAMOTO Tetsuya,KIRIYAMA Yuka,SUZUKI Shugo,SAKURAI Kouhei,TERAMOTO Atsushi,KATO Hiroyuki,NAIKI-ITO Aya,TAHARA Sayumi,TAKAHASHI Satoru
Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃ　Ｐａｔｈｏｌｏｇｙ, 2019
… Six-week-old male rats were intragastrically administered N-methyl-N-nitrosourea (MNU), 3,2′-dimethyl-4-aminobiphenyl (DMAB), dimethylnitrosamine (DMN), and 1,2- dimethylhydrazine (DMH) for 5 days/week for 4 weeks, using corn oil as a vehicle. …
NAID 130007618042

Establishment of an Invasive Prostate Cancer Model in Transgenic Rats by Intermittent Testosterone Administration

Sato Shinya,Suzuki Shugo,Naiki-Ito Aya [他],Naiki-Ito Aya,Komiya Masami,Ne Long,Kato Hiroyuki,Sagawa Hiroyuki,Yamashita Yoriko,Shirai Tomoyuki
Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃ　Ｐａｔｈｏｌｏｇｙ 27(1), 43-49, 2014
… Rats in groups 1 and 3 were given 3,2'-dimethyl-4-aminobiphenyl (DMAB) after TP implantation. …
NAID 130003382476

Related Pictures

Aminobiphenyl File:4-Aminobiphenyl structural formula V Aminobiphenyl-DNA adducts in yl)-4-aminobiphenyl 用途与合成方法 Strukturformel von 2-Aminobiphenyl Aminobiphenyl 97% | Sigma-Aldrich Aminobiphenyl, 97% - Pharmaceutical

★リンクテーブル★

リンク元	「アミノビフェニル」
拡張検索	「4-aminobiphenyl」「aminobiphenyl compound」

「アミノビフェニル」

　　[★]

英: aminobiphenyl
関: 4-aminobiphenyl

「4-aminobiphenyl」

　　[★]

関: 膀胱癌

4-aminobiphenyl is an amine derivative of biphenyl. It is used to manufacture azo dyes. It is a known human carcinogen[2] and so it has been largely replaced by less toxic compounds. It is similar to benzidine.