WordNet

a drug that neutralizes or counteracts the effects of another drug
a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"
the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect (同)endocrine, internal_secretion
stimulating or acting on the adrenal cortex (同)adrenocorticotrophic

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Banerjee RR1, Marina N2, Katznelson L3, Feldman BJ4.
Pediatrics.Pediatrics.2015 Nov;136(5):e1377-81. doi: 10.1542/peds.2015-0684. Epub 2015 Oct 12.
Cushing's syndrome (CS) in the pediatric population is challenging to diagnose and treat. Although next-generation medical therapies are emerging for adults with CS, none are currently approved or used in children. Here we describe the first use of mifepristone, a glucocorticoid receptor antagonist,
PMID 26459648

Peripheral proinflammatory markers associated with ketamine response in a preclinical model of antidepressant-resistance.

Walker AJ1, Foley BM2, Sutor SL3, McGillivray JA4, Frye MA3, Tye SJ5.
Behavioural brain research.Behav Brain Res.2015 Oct 15;293:198-202. doi: 10.1016/j.bbr.2015.07.026. Epub 2015 Jul 21.
Ketamine, N-methyl-d-aspartate (NMDA) receptor antagonist and anti-inflammatory agent, has rapid therapeutic effects in a subset of patients with more intractable forms of depression. Irregular proinflammatory cytokine and acute-reactive protein levels have been reported in clinical and preclinical
PMID 26209292

Effect of salinity changes on olfactory memory-related genes and hormones in adult chum salmon Oncorhynchus keta.

Kim NN1, Choi YJ1, Lim SG2, Jeong M2, Jin DH3, Choi CY4.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.Comp Biochem Physiol A Mol Integr Physiol.2015 Sep;187:40-7. doi: 10.1016/j.cbpa.2015.04.011. Epub 2015 Apr 29.
Studies of memory formation have recently concentrated on the possible role of N-methyl-d-aspartate receptors (NRs). We examined changes in the expression of three NRs (NR1, NR2B, and NR2C), olfactory receptor (OR), and adrenocorticotropic hormone (ACTH) in chum salmon Oncorhynchus keta using quanti
PMID 25933936

Effects of the 5-HT1A Receptor Agonist Tandospirone on ACTH-Induced Sleep Disturbance in Rats

Tsutsui Ryuki,Shinomiya Kazuaki,Sendo Toshiaki,Kitamura Yoshihisa,Kamei Chiaki
Biological and Pharmaceutical Bulletin 38(6), 884-888, 2015
… The aim of this study was to compare the effect of the serotonin (5-HT)1A receptor agonist tandospirone versus that of the benzodiazepine hypnotic flunitrazepam in a rat model of long-term adrenocorticotropic hormone (ACTH)-induced sleep disturbance. … The effect of tandospirone on sleep patterns was antagonized by the 5-HT1A receptor antagonist WAY-100635. …
NAID 130005072657

Retinoic acid receptor-α up-regulates proopiomelanocortin gene expression in AtT20 corticotroph cells

Uruno Akira,Saito-Hakoda Akiko,Yokoyama Atsushi,Kogure Naotaka,Matsuda Ken,Parvin Rehana,Shimizu Kyoko,Sato Ikuko,Kudo Masataka,Yoshikawa Takeo,Kagechika Hiroyuki,Iwasaki Yasumasa,Ito Sadayoshi,Sugawara Akira
Endocrine Journal 61(11), 1105-1114, 2014
… Retinoic acid (RA) has been reported to suppress adrenocorticotropic hormone (ACTH) secretion in Cushing's disease. … Am80 increased Tpit expression while RAR antagonist LE540 suppressed the increase. …
NAID 130004677954

Glucocorticoids Decrease Astrocyte Numbers by Reducing Glucocorticoid Receptor Expression In Vitro and In Vivo

Unemura Kazuhiro,Kume Toshiaki,Kondo Minami [他],MAEDA Yuki,IZUMI Yasuhiko,AKAIKE Akinori
Journal of pharmacological sciences 119(1), 30-39, 2012-05-20
… RU486, a GR antagonist, inhibited the reduction in both astrocyte proliferation and GR expression. … We also examined the effect of excessive glucocorticoid release on GR expression and the number of astrocytes in vivo by administering adrenocorticotropic hormone to rats for 14 days. …
NAID 10030760223