アデノウイルスE3タンパク質
WordNet
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- any of a group of viruses including those that in humans cause upper respiratory infections or infectious pinkeye
- the 5th letter of the Roman alphabet (同)e
PrepTutorEJDIC
- 蛋白(たんばく)質
UpToDate Contents
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English Journal
- Sorting motifs in the cytoplasmic tail of the immunomodulatory E3/49K protein of species D adenoviruses modulate cell surface expression and ectodomain shedding.
- Windheim M1, Höning S2, Leppard KN3, Butler L3, Seed C3, Ponnambalam S4, Burgert HG5.
- The Journal of biological chemistry.J Biol Chem.2016 Feb 3. pii: jbc.M115.684787. [Epub ahead of print]
- The E3 transcription unit of human species C adenoviruses (Ads) encodes immunomodulatory proteins that mediate direct protection of infected cells. Recently, we described a novel immunomodulatory function for E3/49K, an E3 protein uniquely expressed by species D Ads. E3/49K of Ad19a/Ad64, a serotype
- PMID 26841862
- Adenovirus-mediated FIR demonstrated TP53-independent cell-killing effect and enhanced antitumor activity of carbon-ion beams.
- Kano M1, Matsushita K2, Rahmutulla B2, Yamada S3, Shimada H4, Kubo S5, Hiwasa T6, Matsubara H1, Nomura F2.
- Gene therapy.Gene Ther.2016 Jan;23(1):50-6. doi: 10.1038/gt.2015.84. Epub 2015 Aug 4.
- Combination therapy of carbon-ion beam with the far upstream element-binding protein (FBP)-interacting repressor, FIR, which interferes with DNA damage repair proteins, was proposed as an approach for esophageal cancer treatment with low side effects regardless of TP53 status. In vivo therapeutic an
- PMID 26241176
- Efficient induction of cross-presentating human B cell by transduction with human adenovirus type 7 vector.
- Peng Y1, Lai M2, Lou Y2, Liu Y2, Wang H2, Zheng X3.
- Immunology letters.Immunol Lett.2016 Jan;169:41-51. doi: 10.1016/j.imlet.2015.11.011. Epub 2015 Nov 24.
- Although human autologous B cells represent a promising alternative to dendritic cells (DCs) for easy large-scale preparation, the naive human B cells are always poor at antigen presentation. The safe and effective usage record of human adenovirus type 7 (HAdV7) live vaccines makes it attractive as
- PMID 26620361
Japanese Journal
- テロメラーゼ活性を標的とした悪性腫瘍に対するウイルス療法の開発
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- 関
- Ad、adenoviral、Adenoviridae
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