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- the 25th letter of the Roman alphabet (同)y, wye
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- yttriumの化学記号
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/02/01 18:53:43」(JST)
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| Yersinia enterocolitica |
|
| Yersinia enterocolitica colonies growing on XLD agar plates. |
| Scientific classification |
| Kingdom: |
Bacteria |
| Phylum: |
Proteobacteria |
| Class: |
Gamma Proteobacteria |
| Order: |
Enterobacteriales |
| Family: |
Enterobacteriaceae |
| Genus: |
Yersinia |
| Species: |
Y. enterocolitica |
| Binomial name |
Yersinia enterocolitica
(Schleifstein & Coleman 1939) |
| Yersinia enterocolitica |
| Classification and external resources |
| ICD-10 |
A04.6, A04.6 |
| ICD-9 |
008.44 |
| DiseasesDB |
14218 |
| eMedicine |
article/970186 |
| MeSH |
D015009 |
Yersinia enterocolitica is a species of gram-negative coccobacillus-shaped bacterium, belonging to the family Enterobacteriaceae. Yersinia enterocolitica infection causes the disease yersiniosis, which is a zoonotic disease occurring in humans as well as a wide array of animals such as cattle, deer, pigs, and birds. Many of these animals recover from the disease and become asymptomatic carriers.[1] It infects the host by sticking to the cells of the host using Trimeric Autotransporter Adhesins (TAA).
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Contents
- 1 Signs and symptoms
- 2 Treatment
- 3 Prognosis
- 4 References
- 5 External links
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Signs and symptoms
Acute Y. enterocolitica infections usually lead to mild self-limiting entero-colitis or terminal ileitis in humans. Symptoms may include watery or bloody diarrhea and fever. After oral uptake yersiniae replicate in the terminal ileum and invade Peyer's patches. From here yersiniae can disseminate further to mesenteric lymph nodes causing lymphadenopathy. This condition can be confused with appendicitis and is therefore called pseudoappendicitis. In immunosuppressed individuals, yersiniae can disseminate from the gut to liver and spleen and form abscesses. Because Yersinia is a siderophilic (iron-loving) bacteria, people with hereditary hemochromatosis (a disease resulting in high body iron levels) are more susceptible to infection with Yersinia (and other siderophilic bacteria). In fact, the most common contaminant of stored blood is Y. enterocolitica.[2] See yersiniosis for further details. Yersiniae are usually transmitted to humans by insufficiently cooked pork or contaminated water.
Treatment
Yersiniosis is usually self-limiting and does not require treatment. Severe infections (septicemia, focal infection, immunosuppression) can be treated with doxycycline in combination with an aminoglycoside. Other antibiotics that are active against Y. enterocolitica include trimethoprim-sulfamethoxasole, fluoroquinolones, ceftriaxone, and chloramphenicol. Y. enterocolitica is usually resistant to penicillin G, ampicillin, and cephalotin due to beta-lactamase production.[3]
Prognosis
Y. enterocolitica infections are sometimes followed by chronic inflammatory diseases such as arthritis.[4]
Y. enterocolitica seems to be associated with autoimmune Graves-Basedow thyroiditis.[5] Whilst indirect evidence exists, direct causative evidence is limited,[6] and Y. enterocolitica is probably not a major cause of this disease, but may contribute to the development of thyroid autoimmunity arising for other reasons in genetically susceptible individuals.[7] It has also been suggested that Y. enterocolitica infection is not the cause of auto-immune thyroid disease, but rather is only an associated condition; with both having a shared inherited susceptibility.[8] More recently the role for Y. enterocolitica has been disputed.[9]
References
- ^ Collins FM (1996). Pasteurella, and Francisella. In: Barron's Medical Microbiology (Barron S et al., eds.) (4th ed.). Univ of Texas Medical Branch. ISBN 0-9631172-1-1. (via NCBI Bookshelf).
- ^ Goljan, Edward F. Rapid Review Pathology. Second Edition. Page 279, Table 15-1.
- ^ Bottone, Edward (April 1997). "Yersinia enterocolitica: the charisma continues". Clinical Microbiology Reviews (American Society for Microbiology) 10 (2): 257–276. PMC 172919. PMID 9105754. //www.ncbi.nlm.nih.gov/pmc/articles/PMC172919/.
- ^ Ryan KJ; Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. ISBN 0-8385-8529-9.
- ^ Benvenga S, Santarpia L, Trimarchi F, Guarneri F (2006). "Human Thyroid Autoantigens and Proteins of Yersinia and Borrelia Share Amino Acid Sequence Homology That Includes Binding Motifs to HLA-DR Molecules and T-Cell Receptor". Thyroid 16 (3): 225–236. doi:10.1089/thy.2006.16.225. PMID 16571084.
- ^ Tomer Y, Davies T (1993). "Infection, thyroid disease, and autoimmunity" (PDF). Endocr Rev 14 (1): 107–20. doi:10.1210/er.14.1.107. PMID 8491150. http://edrv.endojournals.org/cgi/reprint/14/1/107.pdf.
- ^ Toivanen P, Toivanen A (1994). "Does Yersinia induce autoimmunity?". Int Arch Allergy Immunol 104 (2): 107–11. doi:10.1159/000236717. PMID 8199453.
- ^ Strieder T, Wenzel B, Prummel M, Tijssen J, Wiersinga W (2003). "Increased prevalence of antibodies to enteropathogenic Yersinia enterocolitica virulence proteins in relatives of patients with autoimmune thyroid disease". Clin Exp Immunol 132 (2): 278–82. doi:10.1046/j.1365-2249.2003.02139.x. PMC 1808711. PMID 12699417. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1808711/.
- ^ Hansen P, Wenzel B, Brix T, Hegedüs L (2006). "Yersinia enterocolitica infection does not confer an increased risk of thyroid antibodies: evidence from a Danish twin study". Clin Exp Immunol 146 (1): 32–8. doi:10.1111/j.1365-2249.2006.03183.x. PMC 1809723. PMID 16968395. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1809723/.
External links
- Yersinia enterocolitica genomes and related information at PATRIC, a Bioinformatics Resource Center funded by NIAID
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Infectious diseases · Bacterial diseases: Proteobacterial G− (primarily A00–A79, 001–041, 080–109)
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| α |
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Rickettsiales
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Rickettsiaceae/
(Rickettsioses)
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Typhus
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Rickettsia typhi (Murine typhus) · Rickettsia prowazekii (Epidemic typhus, Brill–Zinsser disease, Flying squirrel typhus)
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Spotted
fever
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Tick-borne
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Rickettsia rickettsii (Rocky Mountain spotted fever) · Rickettsia conorii (Boutonneuse fever) · Rickettsia japonica (Japanese spotted fever) · Rickettsia sibirica (North Asian tick typhus) · Rickettsia australis (Queensland tick typhus) · Rickettsia honei (Flinders Island spotted fever) · Rickettsia africae (African tick bite fever) · Rickettsia parkeri (American tick bite fever) · Rickettsia aeschlimannii (Rickettsia aeschlimannii infection)
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Mite-borne
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Rickettsia akari (Rickettsialpox) · Orientia tsutsugamushi (Scrub typhus)
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Flea-borne
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Rickettsia felis (Flea-borne spotted fever)
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Anaplasmataceae
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Ehrlichiosis: Anaplasma phagocytophilum (Human granulocytic anaplasmosis, Anaplasmosis) · Ehrlichia chaffeensis (Human monocytic ehrlichiosis) · Ehrlichia ewingii (Ehrlichiosis ewingii infection)
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Rhizobiales
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Brucellaceae
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Brucella abortus (Brucellosis)
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Bartonellaceae
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Bartonellosis: Bartonella henselae (Cat scratch disease) · Bartonella quintana (Trench fever) · either henselae or quintana (Bacillary angiomatosis) · Bartonella bacilliformis (Carrion's disease, Verruga peruana)
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| β |
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Neisseriales
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M+ Neisseria meningitidis/meningococcus (Meningococcal disease, Waterhouse-Friderichsen syndrome, Meningococcal septicaemia)
M- Neisseria gonorrhoeae/gonococcus (Gonorrhea)
ungrouped: Eikenella corrodens/Kingella kingae (HACEK) · Chromobacterium violaceum (Chromobacteriosis infection)
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Burkholderiales
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Burkholderia pseudomallei (Melioidosis) · Burkholderia mallei (Glanders) · Burkholderia cepacia complex · Bordetella pertussis/Bordetella parapertussis (Pertussis)
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| γ |
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Enterobacteriales
(OX-)
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Lac+
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Klebsiella pneumoniae (Rhinoscleroma, Klebsiella pneumonia) · Klebsiella granulomatis (Granuloma inguinale) · Klebsiella oxytoca
Escherichia coli: Enterotoxigenic · Enteroinvasive · Enterohemorrhagic · O157:H7 · O104:H4 (Hemolytic-uremic syndrome)
Enterobacter aerogenes/Enterobacter cloacae
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Slow/weak
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Serratia marcescens (Serratia infection) · Citrobacter koseri/Citrobacter freundii
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Lac-
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H2S+
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Salmonella enterica (Typhoid fever, Paratyphoid fever, Salmonellosis)
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H2S-
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Shigella dysenteriae/sonnei/flexneri/boydii (Shigellosis, Bacillary dysentery) · Proteus mirabilis/Proteus vulgaris · Yersinia pestis (Plague/Bubonic plague) · Yersinia enterocolitica · Yersinia pseudotuberculosis
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Pasteurellales
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Haemophilus: H. influenzae (Haemophilus meningitis, Brazilian purpuric fever) · H. ducreyi (Chancroid) H. parainfluenzae (HACEK)
Pasteurella multocida (Pasteurellosis) · Actinobacillus (Actinobacillosis)
Aggregatibacter actinomycetemcomitans (HACEK)
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Legionellales
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Legionella pneumophila/Legionella longbeachae (Legionellosis) · Coxiella burnetii (Q fever)
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Thiotrichales
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Francisella tularensis (Tularemia)
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Vibrionales
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Vibrio cholerae (Cholera) · Vibrio vulnificus · Vibrio parahaemolyticus · Vibrio alginolyticus · Plesiomonas shigelloides
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Pseudomonadales
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Pseudomonas aeruginosa (Pseudomonas infection) · Moraxella catarrhalis · Acinetobacter baumannii
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Xanthomonadales
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Stenotrophomonas maltophilia
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Cardiobacteriales
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Cardiobacterium hominis (HACEK)
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Aeromonadales
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Aeromonas hydrophila/Aeromonas veronii (Aeromonas infection)
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| ε |
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Campylobacterales
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Campylobacter jejuni (Campylobacteriosis, Guillain–Barré syndrome) · Helicobacter pylori (Peptic ulcer, MALT lymphoma) · Helicobacter cinaedi (Helicobacter cellulitis)
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gr+f/gr+a (t)/gr-p (c)/gr-o
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drug (J1p, w, n, m, vacc)
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UpToDate Contents
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Japanese Journal
- Erythema nodosum associated with Yersinia enterocolitica infection
- YOTSU Rie,MII Sumiyuki,HAYASHI Rika,HARADA Harumi,FURUKAWA Keiichi,ETO Hikaru
- Journal of dermatology 37(9), 819-822, 2010-09-01
- NAID 10027067299
Related Links
- Y. enterocolitica has various serotypes for different mammals and each strain has different virulence factors. Biotypes 2 to 5 are less virulent in mice yet account for a majority of human illnesses [11]. Bioserotype 4/O:3 accounts for ...
- ... エルシニア・ペスチス）の他に、食中毒の起因菌であるエルシニア・エンテロコリチカ（Y.enterocolitica ）やエンテロコリチカと同様の急性胃腸炎症状を起こすエルシニア・シュードツベルクローシス（偽結核菌）など数菌種が属して ...
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- ラ
- Yersinia enterocolitica、Y. enterocolitica
- 関
- エルシニア・エンテロコリティカ、エルシニア・エンテロコリチカ
[★]
- ラ
- Yersinia enterocolitica、Y. enterocolitica
- 関
- エンテロコリチカ菌、エルシニア・エンテロコリティカ
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