- 同
- X-linked autoimmunity-allergic dysregulation syndrome
UpToDate Contents
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English Journal
- Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cells.
- Deng G1, Xiao Y, Zhou Z, Nagai Y, Zhang H, Li B, Greene MI.
- Experimental and molecular pathology.Exp Mol Pathol.2012 Dec;93(3):334-8. doi: 10.1016/j.yexmp.2012.09.013. Epub 2012 Oct 2.
- Regulatory T (Treg) cells are essential in preventing the host from developing certain autoimmune diseases and limiting excessive immune responses against pathogens. The normal function of most Treg cells requires sustained expression of functional FOXP3, a member of the FOXP family transcription fa
- PMID 23041265
- FOXP3 and its partners: structural and biochemical insights into the regulation of FOXP3 activity.
- Zhou Z1, Song X, Li B, Greene MI.
- Immunologic research.Immunol Res.2008;42(1-3):19-28. doi: 10.1007/s12026-008-8029-x.
- Forkhead box protein P3 (FOXP3) contributes to a unique transcriptional signature and serves as a functional marker of CD4(+)CD25(+) natural regulatory T cells. Dysfunction of FOXP3 in human is associated with fatal autoimmune disease known as immunodysregulation, polyendocrinopathy, enteropathy, X-
- PMID 18626575
- FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease.
- Li B1, Samanta A, Song X, Iacono KT, Brennan P, Chatila TA, Roncador G, Banham AH, Riley JL, Wang Q, Shen Y, Saouaf SJ, Greene MI.
- International immunology.Int Immunol.2007 Jul;19(7):825-35. Epub 2007 Jun 22.
- We have found that FOXP3 is an oligomeric component of a large supramolecular complex. Certain FOXP3 mutants with single amino acid deletions in the leucine zipper domain of FOXP3 are associated with the X-linked autoimmunity-allergic dysregulation (XLAAD) and immunodysregulation, polyendocrinopathy
- PMID 17586580
Japanese Journal
- FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease
- LI Bin,SAMANTA Arabinda,SONG Xiaomin,IACONO Kathryn T.,BRENNAN Patrick,CHATILA Talal A.,RONCADOR Giovanna,BANHAM Alison H.,RILEY James L.,WANG Qiang,SHEN Yuan,SAOUAF Sandra J.,GREENE Mark I.
- International immunology 19(7), 825-835, 2007-07-01
- NAID 10020109060
Related Links
- Acronym Definition XLAAD X-Linked Autoimmunity-Allergic Disregulation (medical disorder) ... Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational ...
- How is X-Linked Autoimmunity-Allergic Disregulation (medical disorder) abbreviated? XLAAD stands for X-Linked Autoimmunity-Allergic Disregulation (medical disorder). XLAAD is defined as X-Linked Autoimmunity-Allergic Menu ...
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- XLAAD
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- XLAAD
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X連鎖無ガンマグロブリン血症, X-linked agammaglobulinemia