Wiskott-Aldrich syndrome protein family

• ウィスコット・アルドリッチ症候群タンパク質ファミリー、Wiskott-Aldrich症候群タンパク質ファミリー

関

Wiskott-Aldrich syndrome protein

WordNet

1. people descended from a common ancestor; "his family has lived in Massachusetts since the Mayflower" (同)family line, folk, kinfolk, kinsfolk, sept, phratry
2. primary social group; parents and children; "he wanted to have a good job before starting a family" (同)family unit
3. an association of people who share common beliefs or activities; "the message was addressed not just to employees but to every member of the company family"; "the church welcomed new members into its fellowship" (同)fellowship
4. a social unit living together; "he moved his family to Virginia"; "It was a good Christian household"; "I waited until the whole house was asleep"; "the teacher asked how many people made up his home" (同)household, house, home, menage
5. (biology) a taxonomic group containing one or more genera; "sharks belong to the fish family"
6. a pattern of symptoms indicative of some disease
7. a complex of concurrent things; "every word has a syndrome of meanings"
8. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

PrepTutorEJDIC

1. 《集合的に》『家族』,家庭 / 〈U〉《時にa family》(一家の)子供たち / 〈C〉(血縁に関係ある)『親族』,身内,一族,一門 / 〈U〉『家柄』;(特に)名門 / 〈C〉(関係ある人・物の)一団,一群,(生物分類の)科《+『of』+『名』》
2. (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
3. 蛋白(たんばく)質

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• 1. 先天性好中球減少症 congenital neutropenia
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• 4. プロテインＳ欠乏症 protein s deficiency
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English Journal

• APP intracellular domain-WAVE1 pathway reduces amyloid-β production.

• Ceglia I1, Reitz C2,3,4,5, Gresack J1, Ahn JH6,7, Bustos V1, Bleck M8, Zhang X1, Martin G1, Simon SM8, Nairn AC1,9, Greengard P1, Kim Y1.
• Nature medicine.Nat Med.2015 Aug 17. doi: 10.1038/nm.3924. [Epub ahead of print]
• An increase in amyloid-β (Aβ) production is a major pathogenic mechanism associated with Alzheimer's disease (AD), but little is known about possible homeostatic control of the amyloidogenic pathway. Here we report that the amyloid precursor protein (APP) intracellular domain (AICD) downregulates
• PMID 26280122

• Intersectin adaptor proteins are associated with actin-regulating protein WIP in invadopodia.

• Gryaznova T1, Kropyvko S2, Burdyniuk M2, Gubar O2, Kryklyva V2, Tsyba L2, Rynditch A2.
• Cellular signalling.Cell Signal.2015 Jul;27(7):1499-508. doi: 10.1016/j.cellsig.2015.03.006. Epub 2015 Mar 19.
• Invasive cancer cells form actin-rich membrane protrusions called invadopodia that degrade extracellular matrix and facilitate cell invasion and metastasis. WIP (WASP-interacting protein) together with N-WASP (neural Wiskott-Aldrich syndrome protein) are localized in invadopodia and play a crucial r
• PMID 25797047

• Feedback regulation between plasma membrane tension and membrane-bending proteins organizes cell polarity during leading edge formation.

• Tsujita K1, Takenawa T2, Itoh T1.
• Nature cell biology.Nat Cell Biol.2015 Jun;17(6):749-58. doi: 10.1038/ncb3162. Epub 2015 May 4.
• Tension applied to the plasma membrane (PM) is a global mechanical parameter involved in cell migration. However, how membrane tension regulates actin assembly is unknown. Here, we demonstrate that FBP17, a membrane-bending protein and an activator of WASP/N-WASP-dependent actin nucleation, is a PM
• PMID 25938814

Japanese Journal

• Developmental expression of neural Wiskott-Aldrich syndrome protein (N-WASP) and WASP family verprolin-homologous protein (WAVE)-related proteins in postnatal rat cerebral cortex and hippocampus

• TSUCHIYA Daiju,KITAMURA Yoshihisa,TAKATA Kazuyuki,SUGISAKI Tatsuhiko,TANIGUCHI Takashi,UEMURA Kengo,MIKI Hiroaki,TAKENAWA Tadaomi,SHIMOHAMA Shun
• Neuroscience research : the official journal of the Japan Neuroscience Society 56(4), 459-469, 2006-12-01
• NAID 10019273774

• 血小板のアクチン細胞骨格系

• 小田 淳,漆原 範子,宮崎 洋
• 日本血栓止血学会誌 = The Journal of Japanese Society on Thrombosis and Hemostasis 16(6), 599-606, 2005-12-01
• NAID 10020603989

• ストレスタンパク質とミクログリアによるアミロイドβ貪食機能

• 北村 佳久,高田 和幸,谷口 隆之
• 日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA 124(4), 407-413, 2004-10-01
• … ，我々は，ラット培養ミクログリアがAβ1-42（Aβ42）を貪食し分解すること，その貪食には低分子量Gタンパク質のRac1やその下流で働くWiskott-Aldrich syndrome protein family verprolin-homologous protein（WAVE）により制御されるアクチン線維の再構築が関与することを明らかにした．さらに，ミクログリアによるAβ42貪食は，ストレスタ …
• NAID 10014223401

Related Links

• Wiskott-aldrich syndrome protein family | Online references ...

References for "Wiskott-aldrich syndrome protein family" im Internet, an Universitäten und in der Literatur... cyclopaedia.net ... The Wiskott–Aldrich Syndrome Protein (WASp) is a 502-amino acid protein that is expressed in cells of ...

• The Wiskott-Aldrich Foundation

You CAN make a difference. Find out the many ways you can help us in the fight against Wiskott-Aldrich Syndrome. Connect with a family who has already gone through the challenges you face. Search emerging treatments for ...

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★リンクテーブル★

リンク元	「ウィスコット・アルドリッチ症候群タンパク質ファミリー」「Wiskott-Aldrich症候群タンパク質ファミリー」
関連記事	「family」「syndrome」「Aldrich syndrome」

「ウィスコット・アルドリッチ症候群タンパク質ファミリー」

　　[★]

英

Wiskott-Aldrich syndrome protein family

関

ウィスコット・オールドリッチ症候群タンパク質、Wiskott-Aldrich症候群タンパク質ファミリー

「Wiskott-Aldrich症候群タンパク質ファミリー」

　　[★]

英

Wiskott-Aldrich syndrome protein family

関

ウィスコット・アルドリッチ症候群タンパク質ファミリー

「family」

　　[★]

• n.

• (生物)科

　 　 　 　 　 　

「syndrome」

　　[★]

• n.

• 症候群

　 　 　

「Aldrich syndrome」

　　[★] アルドリッチ症候群