WordNet

(meat) cooked until there is just a little pink meat inside
(biology) a substance in which specimens are preserved or displayed
a liquid with which pigment is mixed by a painter
a state that is intermediate between extremes; a middle position; "a happy medium"
an intervening substance through which something is achieved; "the dissolving medium is called a solvent"
(usually plural) transmissions that are disseminated widely to the public (同)mass medium
someone who serves as an intermediary between the living and the dead; "he consulted several mediums" (同)spiritualist, sensitive
a means or instrumentality for storing or communicating information
an intervening substance through which signals can travel as a means for communication
the surrounding environment; "fish require an aqueous medium"
United States singer (1917-1995) (同)Dean Martin, Dino Paul Crocetti
United States actress (1913-1990) (同)Mary Martin
French bishop who is a patron saint of France (died in 397) (同)St. Martin
United States actor and comedian (born in 1945) (同)Steve Martin
any of various swallows with squarish or slightly forked tail and long pointed wings; migrate around Martinmas
Cuban poet and revolutionary who fought for Cuban independence from Spain (1853-1895) (同)Jose Julian Marti

PrepTutorEJDIC

中間(中程度)にあるもの,中庸(mean) / 媒介物,媒体 / 《複数形mediaで》=mass media / 『手段』,方法(means) / (芸術の)表現手段,手法 / (動植物がそこで生存し機能を発揮する)環境;(細菌の)培地,培養基 / 霊媒者 / 『中間の』,並みの
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/03/07 01:29:09」(JST)

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Comparison of two culture media types used to grow Neisseria gonorrhoeae bacteria.

Known as overgrowth, note that the non-selective chocolate agar medium on the left, due to its composition, allowed for the growth of organismal colonies other than those of Neisseria gonorrhoeae, while the selective Thayer-Martin medium on the right, containing antimicrobials that inhibit the growth of organisms other than N. gonorrhoeae, shows no overgrowth, but is positive for N. gonorrhoeae bacteria.

Thayer-Martin agar (or Thayer-Martin medium) is a Mueller-Hinton agar with 5% chocolate sheep blood and antibiotics. It is used for culturing and primarily isolating pathogenic Neisseria bacteria, including Neisseria gonorrhoeae and Neisseria meningitidis, as the medium inhibits the growth of most other microorganisms. When growing Neisseria meningitidis, one usually starts with a normally sterile body fluid (blood or CSF), so a plain chocolate agar is used.

It was characterized in 1964 and 1966.^[1]^[2]^[3]

Components

It usually contains the following combination of antibiotics called VCN inhibitor:

Vancomycin, which is able to kill most Gram-positive organisms, although some Gram-positive organisms such as Lactobacillus and Pediococcus are intrinsically resistant;

Colistin, which is added to kill most Gram-negative organisms except Neisseria, although some other Gram-negative organisms such as Legionella are also resistant;

Nystatin, which can kill most fungi.

SXT, which inhibits Gram-negative organisms, especially swarming proteus

Clinical Implications

A negative culture on Thayer-Martin in a patient exhibiting symptoms of pelvic inflammatory disease most likely indicates an infection with Chlamydia trachomatis

References

^ "THAYER-MARTIN Agar, Base". http://service.merck.de/microbiology/tedisdata/prods/4973-1_10728_0500.html. Retrieved 2009-04-22. ^{[dead link]}
^ THAYER JD, MARTIN JE (January 1964). "A SELECTIVE MEDIUM FOR THE CULTIVATION OF N. GONORRHOEAE AND N. MENINGITIDIS". Public Health Rep 79: 49–57. PMC 1915495. PMID 14105729. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1915495.
^ Thayer JD, Martin JE (June 1966). "Improved medium selective for cultivation of N. gonorrhoeae and N. meningitidis". Public Health Rep 81 (6): 559–62. PMC 1919807. PMID 4957043. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1919807.

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UpToDate Contents

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1. 新生児における淋菌感染症 gonococcal infection in the newborn
2. 滑液検査 synovial fluid analysis
3. 播種性淋菌感染 disseminated gonococcal infection

English Journal

Development and evaluation of a selective medium for Brucella suis.

Ferreira AC, Almendra C, Cardoso R, Pereira MS, Beja-Pereira A, Luikart G, Corrêa de Sá MI.SourceInstituto Nacional de Recursos Biológicos (INRB), I.P./LNIV, Laboratório Nacional de Investigação Veterinária, Estrada de Benfica, 701, 1549-011 Lisboa, Portugal; Universidade de Lisboa, Faculdade de Ciências, Centro de Biodiversidade, Genómica Integrativa e Funcional (BioFIG), Edificio ICAT, Campus da FCUL, Campo Grande, 1749-016 Lisboa, Portugal.
Research in veterinary science.Res Vet Sci.2011 Oct 1. [Epub ahead of print]
A new selective medium, named LNIV-M, has been developed for isolation of Brucella suis. In this work, we evaluated the growth of B. suis reference and field strains from domestic pigs in different basal media and the susceptibility to different antibiotics contained in the currently used Farrell's
PMID 21968103

Development of a selective culture medium for primary isolation of the main Brucella species.

De Miguel MJ, Marín CM, Muñoz PM, Dieste L, Grilló MJ, Blasco JM.SourceUnidad de Sanidad Animal, Centro de Investigación y Tecnología Agroalimentaria (CITA), Gobierno de Aragón, Carretera de Montañana 930, 50059 Zaragoza, Spain.
Journal of clinical microbiology.J Clin Microbiol.2011 Apr;49(4):1458-63. Epub 2011 Jan 26.
Bacteriological diagnosis of brucellosis is performed by culturing animal samples directly on both Farrell medium (FM) and modified Thayer-Martin medium (mTM). However, despite inhibiting most contaminating microorganisms, FM also inhibits the growth of Brucella ovis and some B. melitensis and B. ab
PMID 21270216

Japanese Journal

咽頭材料からのNeisseria gonorrhoeae検出用培地, 変法Thayer-Martin寒天培地(m-TM)の有用性

感染症学雑誌 : 日本伝染病学会機関誌 : the journal of the Japanese Association for Infectious Diseases 75(7), 573-575, 2001-07-20
NAID 10008703573

馬伝染性子宮炎に関する研究 III

日本中央競馬会競走馬総合研究所報告 1983(20), 126-132, 1983
NAID 130004014139

Related Pictures

PPT - Thayer - Martin agar PowerPoint Presentation - ID:554606 Neisseria gonorrhoeae TEM. Transmission electron micrograph of Neisseria gonorrhoeae. Public Domain Picture | Thayer-Martin medium is used when transporting or isolating N Product Catalog Modified Thayer-Martin Agar: Composition, preparation, uses and colony characteristics Morphological Shape Of Neisseria Gonorrhoeae Neisseria - Prac. Microbiology Identification And Differentiation Of Microorganisms