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- 骨粗鬆症、破骨細胞
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- 1. 複合免疫不全combined immunodeficiencies [show details]
…receptor alpha (IL-2RA) chain (CD25) deficiency Signal transducer and activator of transcription 5b (STAT5b) deficiency Winged-helix nude (also called forkhead box N1 [FOXN1]) deficiency Calcium …
- 2. 成長ホルモン不感受性症候群growth hormone insensitivity syndromes [show details]
…by a homozygous missense mutation in the gene encoding signal transducer and activator transcription 5B (STAT5B) , which is essential for normal signaling of the GH receptor . The patients have severe postnatal …
- 3. 成長ホルモンの生理学physiology of growth hormone [show details]
…be a determinant of linear growth patterns, liver enzyme induction, and GH-signaling molecule (STAT 5b) activity . Growth hormone (GH) acts by binding to a specific receptor homodimer, located mostly…
- 4. 胎児・新生児の同種免疫性血小板減少症：母体の評価および妊娠中のマネージメントfetal and neonatal alloimmune thrombocytopenia parental evaluation and pregnancy management [show details]
…antibody) has been detected in approximately 10 percent of HPA-1a negative pregnant women . The HPA-5b antigen is the second most common platelet antigen causing FNAIT in Caucasians . In Asians, the HPA-4 …
- 5. 免疫介在性の新生児血小板減少症neonatal immune mediated thrombocytopenia [show details]
…Another option includes administration of "universal" platelet concentrates that are HPA-1a-negative/HPA-5b-negative . However, these are expensive interventions and are not generally available off-the-shelf…
English Journal
Japanese Journal
- A cross-sectional study exploring useful indicators for low bone mineral density in male alcoholic patients
- The Efficacy of Minodronate in the Treatment of Glucocorticoid-induced Osteoporosis
- Preliminary report : Comparison of Effects of Denosumab and Bisphosphonates on Tartrate-Resistant Acid Phosphatase 5b (TRACP-5b) in Postmenopausal Osteoporosis
Related Links
- ・TRACP-5bは、酸性フォスファターゼのアイソザイム5 に相当し、2つのアイソフォーム、5a と5bのうちの後者です。 ・破骨細胞にのみ存在する酵素で、骨吸収の亢進に伴って血中に漏出することから、骨吸収マーカーとして利用されています。
- TRACP-5b (酒石酸抵抗性酸ホスファターゼ-5b)
- ○ 骨型酒石酸抵抗性酸性フォスファターゼ (TRACP-5b) 項目コード： 6232 0