コットンテイルラビットパピローマウイルス。ショープパピローマウイルス
WordNet
- a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
- (virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
- a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
- a benign epithelial tumor forming a rounded mass (同)villoma, papillary_tumor, papillary tumour
PrepTutorEJDIC
- ビールス,ろ過性病原体
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/24 23:25:19」(JST)
[Wiki en表示]
| Shope papilloma virus |
| Virus classification |
| Group: |
Group I (dsDNA) |
| Family: |
Papillomaviridae |
| Genus: |
Kappapapillomavirus |
| Species: |
Cottontail rabbit papillomavirus |
Rabbit with Shope papillomavirus infection.
Engraving from
Tableau Encyclopedique et Methodique, 1789.
The cottontail rabbit papilloma virus (CRPV), or Shope papilloma virus, is a type I virus under the Baltimore scheme, possessing a nonsegmented dsDNA genome.[1] The virus was originally separated from horny warts on cottontail rabbits by Richard E. Shope in 1933.[2] It infects rabbits, causing keratinous carcinomas, typically on or near the animal’s head. These tumors can become large enough that they interfere with the host’s ability to eat, eventually causing starvation.
Shope papilloma virus provided the first mammalian model of a cancer caused by a virus. It takes its name from Shope, who discovered it in the 1930s.[2] Shope was able to isolate virus particles from tumors on captured animals and use these to inoculate domestic rabbits, which then developed similar tumors.[3] The virus was sequenced in 1984, showing substantial sequence similarities to HPV1a.[4] It has been used as a model for human papillomaviruses both before and after this discovery. The most visible example of this role is the HPV vaccine, which was developed based on and incorporating research done using the virus as a model. Similarly, it has been used to investigate antiviral therapies.[5]
The virus is also a possible source of myths about the jackalope, a rabbit with the horns of an antelope, and related cryptids such as the wolpertinger.[6][7] Stories and illustrations of horned rabbits appear in scientific treatises dating back many years, such as the Tableau encyclopédique et méthodique, from 1789.[8]
References
- ^ "Cottontail rabbit papillomavirus" in UniProt
- ^ a b Shope RE, Hurst EW (1933). "Infectious papillomatosis of rabbits: with a not on the histopathology". J. Exp. Med. 58 (5): 607–624. doi:10.1084/jem.58.5.607. PMID 19870596.
- ^ http://www.ratsteachmicro.com/2003_HCOE_PDFs/Papovavirus_Lecture_Outline__2005rev.pdf
- ^ Giri, Isabelle; Danos, Olivier; Yaniv, Moshe (1985), "Genomic Structure of the Cottontail Rabbit (Shope) Papillomavirus" (PDF), PNAS 82 (6): 1580–1584, doi:10.1073/pnas.82.6.1580
- ^ Christensen ND, ND (2005), "Genomic Structure of the Cottontail Rabbit (Shope) Papillomavirus", Antivir Chem Chemother 16 (6): 355–62, PMID 16331841
- ^ Eberhart, George M. "Mysterious Creatures: Creating A Cryptozoological Encyclopedia." 2005. Journal of Scientific Exploration. Vol. 19, No. 1, pp. 103-113
- ^ Eberhart, George M. (2002), Mysterious Creatures: A Guide to Cryptozoology 1, ABC-CLIO, pp. 237–238, ISBN 1-57607-283-5
- ^ "Cottontail rabbit papillomavirus was the first mammalian papillomavirus to be discovered"
UpToDate Contents
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English Journal
- Ranpirnase eradicates human papillomavirus in cultured cells and heals anogenital warts in a Phase I study.
- Squiquera L1, Taxman DJ1, Brendle SA2, Torres R1, Sulley J1, Hodge T1, Christensen N2, Sidransky D1.
- Antiviral therapy.Antivir Ther.2017 Jan 25. doi: 10.3851/IMP3133. [Epub ahead of print]
- PMID 28121292
- Host genetic influence on papillomavirus-induced tumors in the horse.
- Staiger EA1, Tseng CT2, Miller D2, Cassano JM2, Nasir L3, Garrick D4, Brooks SA5, Antczak DF2.
- International journal of cancer.Int J Cancer.2016 Aug 15;139(4):784-92. doi: 10.1002/ijc.30120. Epub 2016 May 6.
- PMID 27037728
- Model systems of human papillomavirus-associated disease.
- Doorbar J1.
- The Journal of pathology.J Pathol.2016 Jan;238(2):166-79. doi: 10.1002/path.4656. Epub 2015 Dec 10.
- PMID 26456009
Japanese Journal
- Shope Papilloma による tRNA の in vitro Methylation
- The shope papilloma-carcinoma complex as a model for investigation of tumor immunology and viral oncology.
- THE SHOPE PAPILLOMA-CARCINOMA COMPLEX AS A MODEL FOR INVESTIGATION OF TUMOR IMMUNOLOGY AND VIRAL ONCOLOGY
Related Links
- Shope pap·il·lo·ma vi·rus (shōp), a papillomavirus infecting wild cottontail rabbits. See: Shope papilloma. Shope, Richard E., U.S. pathologist, 1902-1966. Shope fibroma - a connective tissue tumor of cottontail rabbits caused by a ...
- Shope pap·il·lo·ma vi·rus (shōp), a papillomavirus infecting wild cottontail rabbits. See: Shope papilloma. Shope, Richard E., U.S. pathologist, 1902-1966. Shope fibroma - a connective tissue tumor of cottontail rabbits caused by a ...
★リンクテーブル★
[★]
- 英
- cottontail rabbit papilloma virus, CRPV
- 同
- ショープパピローマウイルス ショープ乳頭腫ウイルス Shope papilloma virus
[★]
ショープ乳頭腫、Shope乳頭腫
- 関
- Shope fibroma、tumor virus infection
[★]
- 関
- papillomavirus
[★]
ウイルス