ショープ乳頭腫、Shope乳頭腫
- 関
- Shope fibroma、tumor virus infection
WordNet
- a benign epithelial tumor forming a rounded mass (同)villoma, papillary_tumor, papillary tumour
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/06 12:53:54」(JST)
[Wiki en表示]
| Shope papilloma virus |
| Virus classification |
| Group: |
Group I (dsDNA) |
| Family: |
Papillomaviridae |
| Genus: |
Kappapapillomavirus |
| Species: |
Kappapapillomavirus 2 |
| Synonyms |
|
Cottontail rabbit papillomavirus, Cottontail rabbit papillomavirus (Shope), and Rabbit (Shope) papilloma virus
|
Rabbit with Shope papillomavirus infection.
Engraving from
Tableau Encyclopedique et Methodique, 1789.
The cottontail rabbit papilloma virus (CRPV), or Shope papilloma virus (also known as Kappapapillomavirus 2, Cottontail rabbit papillomavirus, and Rabbit (Shope) papilloma virus), is a type I virus under the Baltimore scheme, possessing a nonsegmented dsDNA genome.[1] The virus was originally separated from horny warts on cottontail rabbits by Richard E. Shope in 1933.[2] It infects rabbits, causing keratinous carcinomas, typically on or near the animal’s head. These tumors can become large enough that they interfere with the host’s ability to eat, eventually causing starvation.
Shope papilloma virus provided the first mammalian model of a cancer caused by a virus. It takes its name from Shope, who discovered it in the 1930s.[2] Shope was able to isolate virus particles from tumors on captured animals and use these to inoculate domestic rabbits, which then developed similar tumors.[3] The virus was sequenced in 1984, showing substantial sequence similarities to HPV1a.[4] It has been used as a model for human papillomaviruses both before and after this discovery. The most visible example of this role is the HPV vaccine, which was developed based on and incorporating research done using the virus as a model. Similarly, it has been used to investigate antiviral therapies.[5]
The virus is also a possible source of myths about the jackalope, a rabbit with the horns of an antelope, and related cryptids such as the wolpertinger.[6][7] Stories and illustrations of horned rabbits appear in scientific treatises dating back many years, such as the Tableau encyclopédique et méthodique, from 1789.[8]
See also
Oncovirus (cancer virus)
References
- ^ "Cottontail rabbit papillomavirus" in UniProt
- ^ a b Shope RE, Hurst EW (1933). "Infectious papillomatosis of rabbits: with a not on the histopathology". J. Exp. Med. 58 (5): 607–624. doi:10.1084/jem.58.5.607. PMID 19870596.
- ^ http://www.ratsteachmicro.com/2003_HCOE_PDFs/Papovavirus_Lecture_Outline__2005rev.pdf
- ^ Giri, Isabelle; Danos, Olivier; Yaniv, Moshe (1985), "Genomic Structure of the Cottontail Rabbit (Shope) Papillomavirus" (PDF), PNAS 82 (6): 1580–1584, doi:10.1073/pnas.82.6.1580
- ^ Christensen ND, ND (2005), "Genomic Structure of the Cottontail Rabbit (Shope) Papillomavirus", Antivir Chem Chemother 16 (6): 355–62, PMID 16331841
- ^ Eberhart, George M. "Mysterious Creatures: Creating A Cryptozoological Encyclopedia." 2005. Journal of Scientific Exploration. Vol. 19, No. 1, pp. 103-113
- ^ Eberhart, George M. (2002), Mysterious Creatures: A Guide to Cryptozoology 1, ABC-CLIO, pp. 237–238, ISBN 1-57607-283-5
- ^ "Cottontail rabbit papillomavirus was the first mammalian papillomavirus to be discovered"
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Japanese Journal
- Shope Papilloma による tRNA の in vitro Methylation
- 3.単癌ウサギに於ける補体の動態(第3回補体シンポジウム III 補体とその関連領域)
- 吉田 孝人,伊藤 洋平
- アレルギー 15(11), 926-927, 947, 1966-11-30
- … Immunological experiments employing Shope papilloma-carcinoma system are now being carried out in our group. … In the present paper we report our findings on the alteration of complement value (C'H_<50>) in the tumor-bearing rabbit, which were transplanted with carcinoma (ca) V×2, and (ca) V×7, both being neoplasia of Shope papilloma origin. …
- NAID 110002428488
- The shope papilloma-carcinoma complex as a model for investigation of tumor immunology and viral oncology.
Related Links
- Shope named after R. E. Shope, American virologist. Shope fibroma see Shope rabbit fibroma. Shope papilloma caused by a papilloma virus and manifested by gray to black, tall, thin, horny structures on the skin of wild rabbits. The ...
- SHOPE PAPILLOMA suggested the stage of heterotransplantable from shope carcinomas caused. Polyoma virus interferon-likethe state of tion . Present in situated mainly, perhaps entirely. Gives you evidencefluorescein-globulin ...
★リンクテーブル★
[★]
- 英
- Shope papilloma
- 関
- 腫瘍ウイルス感染症、ショープ線維腫、Shope乳頭腫
[★]
ショープ線維腫、Shope線維腫
- 関
- Shope papilloma、tumor virus infection
[★]
腫瘍ウイルス感染症
- 関
- Shope fibroma、Shope papilloma
[★]
- 英
- Shope papilloma
- 関
- ショープ乳頭腫
[★]
コットンテイルラビットパピローマウイルス。ショープパピローマウイルス