English Journal

Acoustic quantification of ATP using a quartz crystal microbalance with dissipation.

Ozalp VC.SourcePolymat, University of the Basque Country, Avda. Tolosa, 78, 20018, San Sebastian-Donostia, Spain. velicengiz.ozal@ehu.es.
The Analyst.Analyst.2011 Dec 7;(23):5046-50. Epub 2011 Oct 17.
A quartz crystal microbalance with a dissipation monitoring (QCM-D) sensor was developed for highly sensitive and specific detection of adenosine-5'-triphosphate (ATP) by using an aptamer. The binding of ATP molecules on the aptamer films could be calculated as accurate mass changes using multiple f
PMID 22005829

Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells.

Yegutkin GG, Helenius M, Kaczmarek E, Burns N, Jalkanen S, Stenmark K, Gerasimovskaya EV.SourceMediCity Research Laboratory, University of Turku and National Institute of Health and Welfare, Tykistökatu 6A, 20520, Turku, Finland, genyeg@utu.fi.
Angiogenesis.Angiogenesis.2011 Dec;14(4):503-13. Epub 2011 Sep 16.
Vascular remodeling plays a pivotal role in a variety of pathophysiological conditions where hypoxia and inflammation are prominent features. Intravascular ATP, ADP and adenosine are known as important regulators of vascular tone, permeability and homeostasis, however contribution of purinergic sign
PMID 21922294

Japanese Journal

Thrombin Activates Ca2+-permeating Nonselective Cation Channels through Protein Kinase C in Human Umbilical Vein Endothelial Cells

Tsujino Natsuko,Nakada Tsutomu,Tsubouchi Kiyotaka [他]
信州医学雑誌 59(1), 13-26, 2011
… A Ca chelater, BAPTA-AM (10μM), significantly inhibited the thrombin-induced contraction of HUVECs.Thrombin induced inward currents at -60 mV in the presence of intracellular MgATP. …
NAID 120002771794

The covalent modification of spectrin in red cell membranes by the lipid peroxidation product 4-hydroxy-2-nonenal

Arashiki Nobuto,Otsuka Yayoi,Ito Daisuke,Yang Mira,Komatsu Tomohiko,Sato Kota,Inaba Mutsumi
Biochemical and Biophysical Research Communications 391(3), 1543-1547, 2010-01-15
… The level of HNE adducts in spectrin(particularly α-spectrin) and several other membrane proteins was increased following the HNE treatment of red cell membrane ghosts prepared in the absence of MgATP. … In contrast, ghost preparation in the presence of MgATP reduced HNE adduct formation, with preferential β-spectrin modification and increased cross-linking of the HNE-modified spectrins. …
NAID 120002317142