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1. メルケル細胞（神経内分泌）癌の病因、臨床的特徴、および診断pathogenesis clinical features and diagnosis of merkel cell neuroendocrine carcinoma [show details]
… ribbon-like arrangement. Ultrastructurally, MCC tumor cells, like normal Merkel cells, contain paranuclear electron-dense neurosecretory granules (dense core granules), 10 mm filaments, and desmosomes . MCC may …
2. メルケル細胞癌の病期分類および治療staging and treatment of merkel cell carcinoma [show details]
… Merkel cell carcinoma (MCC) of the skin is a rare, aggressive cutaneous malignancy that predominantly affects Caucasians over age 50 and has a propensity for local recurrence and regional lymph node metastases …
3. 皮下蜂窩織炎様T細胞性リンパ腫の臨床症状、病理学的特徴、および診断clinical manifestations pathologic features and diagnosis of subcutaneous panniculitis like t cell lymphoma [show details]
… express CD3, CD8, and the alpha/beta T cell receptor (TCR), and are negative for CD4 and CD56. There is strong expression of the cytotoxic granule proteins granzyme B, T cell intracellular antigen (TIA)-1, and …
4. NK細胞欠損症候群：臨床症状および診断nk cell deficiency syndromes clinical manifestations and diagnosis [show details]
…fusion and secretion of NK cell lytic granules with the NK cell membrane where it touches the target cell. This contact leads to secretion of lytic granule contents onto the target cell to promote cytotoxicity …
5. 実質臓器移植受容者における皮膚癌の疫学および危険因子epidemiology and risk factors for skin cancer in solid organ transplant recipients [show details]
…human papillomavirus (HPV), Kaposi sarcoma herpes virus (KSHV), human T cell lymphotropic virus type 1 (HTLV-1), and Merkel cell polyomavirus (MCV) are the main viruses associated with the development …

English Journal

Study on the Role of Histochemical Stains in Identifying Merkel Cells in Dogs.

Ramírez GA, de Los Monteros AE.
Anatomical record (Hoboken, N.J. : 2007). 2018 Oct;().
Merkel cells (MCs) are neuroendocrine cells involved with tactile sense, growth, differentiation, and homeostasis of the skin as well as in different cutaneous diseases. Specific staining techniques are required for their identification because they are not easily visible in paraffin sections staine
PMID 30378297

Light and electron microscopic observations on the organization of skin and associated glands of two caecilian amphibians from Western Ghats of India.

Damodaran A, Reston Saroja B, Kotharambath R, Mohammad Abdulkader A, Oommen OV, Lekha D.
Micron (Oxford, England : 1993). 2018 03;106()59-68.
We adopted light and electron microscopy to understand the structure of the skin of two species of caecilians, Ichthyophis tricolor and Uraeotyphlus cf. oxyurus, from Western Ghats of Kerala, India. The surface of the skin of these caecilians contains an irregular pattern of microridges. Oval, round
PMID 29353148

Merkel Cell Carcinoma in a Steer.

Teh APP, Izzati UZ, Diep NV, Hirai T, Yamaguchi R.
Journal of comparative pathology. 2018 Jan;158()17-21.
Merkel cell carcinoma is a rare and aggressive cutaneous neuroendocrine tumour reported only in man, dogs and cats. A 20-month-old Japanese black fattening steer was presented with necrotic protruding skin masses over the left thoracic area and a 20 × 25 cm subcutaneous mass in the left abdomina
PMID 29422311

Japanese Journal

メルケル細胞癌に対する放射線単独治療 : 症例報告と本邦報告例のまとめ

牧野英一,笹江舞子,笹岡俊輔,稲沖真,藤本亘,平塚純一
Skin cancer : official organ of the Japanese Society for Skin Cancer = 皮膚悪性腫瘍研究会機関誌 20(3), 329-333, 2006-02-15
… 腫瘍細胞は小型で細胞質に乏しくCK20染色陽性で, 電顕像にて細胞質辺縁に電子密度の高い顆粒 (dense core granule) を認めた。 …
NAID 10019606739

皮下腫りゅうとして出現し急速に増大したメルケル細胞癌の１例

東奈津子,前川直輝,寺前浩之,村上智子,古川雅祥,石井正光
皮膚 43(4/5), 249-252, 2001
NAID 130004046124

耳介に発生したメルケル細胞癌の１症例

実吉健策,稲葉岳也,中村将裕,山口展正,遠藤泰彦
耳鼻咽喉科展望 43(2), 127-130, 2000
今回我々は耳介に発生したメルケル細胞癌の1例を経験した。組織学的に真皮上層から皮下組織にかけて索状構造を示す腫瘍で, 免疫組織学的にNeuron Specific Enolase (NSE) 陽性を示し, 電顕的に腫瘍細胞の細胞質にメルケル細胞顆粒と同様の暗調球形顆粒が認められたため, メルケル細胞癌と診断した。腫瘍を含めた耳介全切除術を施行し, 術後に腫瘍切除部および所属リンパ節に対して予防照射 …
NAID 130003975161